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Loss of suppressor-of-fused function promotes tumorigenesis.

author

Tom Curran

1956 -

published in: Oncogene

date of publication: 2007-04-23

language: English

Cites articles 24

Date

Title

Authors

2006-01-01

The hedgehog pathway and neurological disorders

Tom Curran, Lee L Rubin
2006-07-01

Patched2 modulates tumorigenesis in patched1 heterozygous mice

Tom Curran, Kelli L. Boyd
2006-04-01

Shh pathway activity is down-regulated in cultured medulloblastoma cells: implications for preclinical studies

Tom Curran
2006-02-01

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway

Johan Ericson, Karin Heby-Henricson, Rune Toftgård, Stephan Teglund, Björn Rozell, Jessica Svärd, Madelen Persson-Lek, Matthias Lauth
2006-02

Divergence of hedgehog signal transduction mechanism between Drosophila and mammals

Markku Varjosalo
2006-05-02

XRCC4 suppresses medulloblastomas with recurrent translocations in p53-deficient mice
2005-08-01

Mice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic development
2005-10-01

Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused
2005-11-14

Hedgehog checkpoints in medulloblastoma: the chromosome 17p deletion paradigm

Elisabetta Ferretti, Enrico De Smaele
2005-04-01

Communicating with Hedgehogs
2005-06-01

Gli1 is important for medulloblastoma formation in Ptc1+/- mice

Tom Curran
2005-01

Medulloblastoma: developmental mechanisms out of control
2005-04-20

Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma

Trudy G Oliver, Tracy-Ann Read
2004-11-01

MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription

Lily Horng
2004-07-12

REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

Elisabetta Ferretti, Enrico De Smaele, Francesca Zazzeroni, Felice Giangaspero
2004-06-18

The Hedgehog response network: sensors, switches, and routers
2004-03-01

The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins
2004-09-01

Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

Tom Curran, Lee L Rubin
2003-02-14

Characterization of the physical interaction of Gli proteins with SUFU proteins
2002-04-01

Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex
2002-06-17

Mutations in SUFU predispose to medulloblastoma

Jeremy A. Squire, Stephen W. Scherer, James Rutka
2000-07-01

The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells.

Greg N. Fuller
1997-08-22

Altered neural cell fates and medulloblastoma in mouse patched mutants
1994-01-01

Tumor spectrum analysis in p53-mutant mice

Bart O Williams

Article - wd:Q53334228

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