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From TCR Engagement to T Cell Activation

author

Antonella Viola

1969 -

Antonio Lanzavecchia

1951 -

published in: Cell

date of publication: 1999-01-01

language: English

main subject: T cell activation

Cites articles 29

Date

Title

Authors

1998-10-01

Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]
1998-01-01

Ligand recognition by alpha beta T cell receptors.
1998-10-01

CD8 expression allows T cell signaling by monomeric peptide-MHC complexes

Jérôme Delon, Bernard Malissen
1998-01-01

The duration of antigenic stimulation determines the fate of naive and effector T cells.
1998-07-24

Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation
1998-09-03

Three-dimensional segregation of supramolecular activation clusters in T cells
1998-09-01

Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains
1998-07-01

An unusual mechanism for ligand antagonism
1998-07-01

CD28 affects the earliest signaling events generated by TCR engagement.

Loretta Tuosto
1998-06-01

Membrane compartmentation is required for efficient T cell activation.
1998-08

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation
1997-02-01

Requirements for peptide-induced T cell receptor downregulation on naive CD8+ T cells
1997-08-29

Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells
1997-01-01

The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands
1997-05-01

Altered hapten ligands antagonize trinitrophenyl-specific cytotoxic T cells and block internalization of hapten-specific receptors
1997-04-01

Making the T cell receptor go the distance: a topological view of T cell activation

Michael L Dustin
1997-06-05

Functional rafts in cell membranes

Kai Simons
1997-11-01

Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering

Loretta Tuosto, Mariolina Salio, Antonio Lanzavecchia
1997-11-01

A T cell receptor (TCR) antagonist competitively inhibits serial TCR triggering by low-affinity ligands, but does not affect triggering by high-affinity anti-CD3 antibodies

Antonella Viola, Antonio Lanzavecchia
1996-04-01

Essential flexibility in the T-cell recognition of antigen
1996-02-01

Kinetic discrimination in T-cell activation
1996-06-01

Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response
1996-10-01

Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression
1996-04-01

Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy

Salvatore Valitutti, Sabina Müller, Antonio Lanzavecchia
1996-07-01

T cell activation determined by T cell receptor number and tunable thresholds

Antonella Viola, Antonio Lanzavecchia
1995-10-01

CD28 and apoptosis
1995-05-01

Kinetic proofreading in T-cell receptor signal transduction
1995-02-01

Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton

Salvatore Valitutti, Antonio Lanzavecchia
1995-05-01

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

Antonio Lanzavecchia

Article - wd:Q57363708

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