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Microenvironmental niche divergence shapes BRCA1-dysregulated ovarian cancer morphological plasticity

Autor

Andrea Sottoriva

Anguraj Sadanandam

Katherine Eason

Yinyin Yuan

Stefano Lise

Marco Punta

veröffentlicht in: Nature Communications

Erscheinungsdatum: 2018-09-25

Sprache: Englisch

Hauptthema: allgemeine Chemie, Ovarialkarzinom

Zitiert Artikel 70

Datum

Titel

Autor

2017-07-17

Hyper-Stain Inspector: A Framework for Robust Registration and Localised Co-Expression Analysis of Multiple Whole-Slide Images of Serial Histology Sections

Nasir M. Rajpoot, Ian A Cree, Nicholas Trahearn
2016-09-19

Similarity and diversity of the tumor microenvironment in multiple metastases: critical implications for overall and progression-free survival of high-grade serous ovarian cancer

Yinyin Yuan
2016-08-01

Spatial Heterogeneity in the Tumor Microenvironment

Yinyin Yuan
2016-06-27

A Strong B-cell Response Is Part of the Immune Landscape in Human High-Grade Serous Ovarian Metastases

Anne Montfort, Fran Balkwill, Jonathan S. Serody, Melania Capasso, Probir Chakravarty, Benjamin G Vincent, Steffen Böhm, Thomas Dowe, Joanne Topping, Michelle Lockley
2016-06-06

The Ensembl Variant Effect Predictor

William M McLaren, Sarah E. Hunt, Paul Flicek, Fiona Cunningham, Anja Thormann, Laurent Gil, Harpreet Singh Riat, Graham R. S. Ritchie
2016-03-30

NetMHCpan-3.0; improved prediction of binding to MHC class I molecules integrating information from multiple receptor and peptide length datasets

Massimo Andreatta, Morten Nielsen
2016-03-08

Characteristics of 10-year survivors of high-grade serous ovarian carcinoma

Jenny Lester, Anil Sood
2016-01-13

Tumor-Infiltrating Plasma Cells Are Associated with Tertiary Lymphoid Structures, Cytolytic T-Cell Responses, and Superior Prognosis in Ovarian Cancer

Brad H Nelson, Katy Milne, David Li-Kroeger
2015-12-04

Systematic pan-cancer analysis of tumour purity

Dvir Aran, Atul Butte, Marina Sirota
2015-11-30

Pan-cancer analysis of the extent and consequences of intratumor heterogeneity

Trevor A Graham, Marnix Jansen, Li Xia
2015-11-17

Quantitative histology analysis of the ovarian tumour microenvironment

Xi Lan, Yinyin Yuan, Susana Banerjee
2015-09-22

An ecological measure of immune-cancer colocalization as a prognostic factor for breast cancer

Rachael Natrajan, Yinyin Yuan
2015-09-15

Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes

Kristian Cibulskis, Carrie Sougnez, Gad Getz, Nir Hacohen, Vladimir Brusic
2015-03-01

Cell shape and the microenvironment regulate nuclear translocation of NF-κB in breast epithelial and tumor cells

Julia E Sero, Rico Ardy, Chris Bakal
2015-06-19

APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity

Nicholas McGranahan, Charles Swanton, Reuben S Harris
2015-03-30

Robust enumeration of cell subsets from tissue expression profiles

Aaron M. Newman, Michael Green, Andrew J Gentles, A Alizadeh, Chih Long Liu, Maximilian Diehn
2015-04-20

limma powers differential expression analyses for RNA-sequencing and microarray studies

Matthew E Ritchie, Belinda Phipson, Gordon K Smyth
2014-12-17

Combined image and genomic analysis of high-grade serous ovarian cancer reveals PTEN loss as a common driver event and prognostic classifier

James D Brenton, Florian Markowetz, Paul D P Pharoah
2014-12-31

Integrative network analysis of TCGA data for ovarian cancer

Joanna E Burdette
2014-07-13

Integrating mapping-, assembly- and haplotype-based approaches for calling variants in clinical sequencing applications

Andrew Oliver Mungo Wilkie, Gerton Lunter, Stephen Twigg, Zamin Iqbal, Hang Phan
2014-06-10

Prognostic B-cell signatures using mRNA-seq in patients with subtype-specific breast and ovarian cancer

Charles M. Perou, Jonathan S. Serody, Benjamin G Vincent
2014-06-01

A nonlinear mapping approach to stain normalization in digital histopathology images using image-specific color deconvolution

Darren Treanor, Derek R Magee, Nasir M. Rajpoot
2014-01-02

AbsCN-seq: a statistical method to estimate tumor purity, ploidy and absolute copy numbers from next-generation sequencing data
2014-01-06

Global dynamic optimization approach to predict activation in metabolic pathways

Edda Klipp, Julio R. Banga
2013-01-01

Inferring tumour purity and stromal and immune cell admixture from expression data

Gad Getz, Hoon Kim, Kosuke Yoshihara, Gordon B. Mills
2013-09-19

Influence of tumour micro-environment heterogeneity on therapeutic response
2013-04-02

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

Chris Sander, Bülent Arman Aksoy, Gideon Dresdner, Ethan Cerami, Ugur Dogrusoz, Anders Jacobsen, Rileen Sinha, Jianjiong Gao, Nikolaus Schultz
2013-03-01

When lamins go bad: nuclear structure and disease

Brian K Kennedy
2013-02-10

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

Carrie Sougnez, Kristian Cibulskis, Gad Getz, Stacey Gabriel, Eric Lander, Matthew Meyerson, Andrey Sivachenko
2013-01-10

New strategies in the treatment of ovarian cancer: current clinical perspectives and future potential

Susana Banerjee
2013-06

A GIS-based risk rating of forest insect outbreaks using aerial overview surveys and the local Moran's I statistic

Joanne C. White, Michael A. Wulder, Trisalyn Nelson
2012-12-21

Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

Carrie Sougnez, Kristian Cibulskis, Gordon Saksena, Gad Getz, Stacey Gabriel, Lynda Chin, Jill P. Mesirov, Keren Levanon, Aleksandar David Kostić, Aviad Tsherniak, Martin Köbel, Anna deFazio, Ronny Drapkin, David Bowtell, Robert A Soslow, Cancer Genome Atlas Research Network, Matthew Meyerson, Craig H Mermel, Pablo Tamayo, Douglas A Levine, Roel G W Verhaak, Ari E Kahn, Paul Spellman, Scott L Carter, Joe W Gray

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