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Synthesis, characterization and biological activity of organometallic derivatives of the antimalarial drug mefloquine as new antischistosomal drug candidates

författare

Jeannine Hess

Gordana Panic

Marta Jakubaszek

Jennifer Keiser

Gilles Gasser

1976 -

publicerad i: MedChemComm

utgivningsår: 2018-10-10

huvudämne: Meflokin

Refererar artiklar 39

Datum

Titel

Författare

2017-07-18

Ferrocenyl, Ruthenocenyl, and Benzyl Oxamniquine Derivatives with Cross-Species Activity against Schistosoma mansoni and Schistosoma haematobium

Jeannine Hess, Gordana Panic, Bernhard Spingler, Gilles Gasser, Malay Patra
2016-03-11

Sedaxicenes: potential new antifungal ferrocene-based agents?

Gilles Gasser
2016-03-15

Bimodal X-ray and Infrared Imaging of an Organometallic Derivative of Praziquantel in Schistosoma mansoni

Malay Patra, Jeannine Hess, Gilles Gasser, Clotilde Policar, Riccardo Rubbiani
2016-06-20

Discovery of Antischistosomal Drug Leads Based on Tetraazamacrocyclic Derivatives and Their Metal Complexes

Jennifer Keiser, Mireille Vargas
2016-10-05

Organometallic Derivatization of the Nematocidal Drug Monepantel Leads to Promising Antiparasitic Drug Candidates.

Jeannine Hess, Abdul Jabbar, Gilles Gasser, Loganathan Rangasamy, Robin B. Gasser, Malay Patra, Sandro Konatschnig
2015-01-01

Toward organometallic antischistosomal drug candidates

Jeannine Hess, Gilles Gasser
2015-10-21

Ferrocifen type anti cancer drugs

Gérard Jaouen, Anne Vessieres, Siden Top
2014-06-21

Schistosomiasis control: praziquantel forever?
2014-06-30

Activity of praziquantel enantiomers and main metabolites against Schistosoma mansoni

Isabel Meister, Murray N Robertson, Malay Patra, Gilles Gasser, Matthew H. Todd
2014-07

Praziquantel, mefloquine-praziquantel, and mefloquine-artesunate-praziquantel against Schistosoma haematobium: a randomized, exploratory, open-label trial

Jürg Utzinger, Jennifer Keiser, Eliézer K N'Goran, Nicaise A N'Guessan, Kigbafori D Silué, Lukas G Adiossan
2014-01-01

Ferroquine as an oxidative shock antimalarial

Christophe Biot
2014-10-01

Prevention and control of schistosomiasis: a current perspective
2013-01-07

[(η(6)-Praziquantel)Cr(CO)3] derivatives with remarkable in vitro anti-schistosomal activity.

Stefano Ferrari, Bernhard Spingler, Gilles Gasser, Robin B. Gasser
2013-08-27

Mefloquine, a new type of compound against schistosomes and other helminthes in experimental studies
2013-11-12

In vitro metabolic profile and in vivo antischistosomal activity studies of (η(6)-praziquantel)Cr(CO)3 derivatives

Gilles Gasser, Matthew H. Todd, Murray N Robertson
2012-10-10

Ferrocenyl derivatives of the anthelmintic praziquantel: design, synthesis, and biological evaluation

Malay Patra, Stefano Ferrari, Bernhard Spingler, Gilles Gasser
2012-10-07

Susceptibility or resistance of praziquantel in human schistosomiasis: a review
2011-01-07

The antimalarial ferroquine: role of the metal and intramolecular hydrogen bond in activity and resistance

Sergey Kapishnikov, Faustine Dubar, Christine Pierrot, Jamal Khalife, Christophe Biot, Hervé Vezin, Bruno Pradines, Christophe Rogier, Leslie Leiserowitz
2011-08-01

The antimalarial ferroquine: from bench to clinic

Jamal Khalife, Christophe Biot
2011-11-21

In vivo activity of aryl ozonides against Schistosoma species

Jacques Chollet, Jennifer Keiser, Mireille Vargas
2010-05-01

Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, and praziquantel against Schistosoma haematobium: randomized, exploratory open-label trial

Jürg Utzinger, Penelope Vounatsou, Christoph Hatz, Eliézer K N'Goran, Jennifer Keiser, Nicaise A N'Guessan, Kigbafori D Silué
2010-11-15

Organometallic anticancer compounds

Gilles Gasser, Ingo Ott, Nils Metzler-Nolte
2009

Mefloquine--an aminoalcohol with promising antischistosomal properties in mice

Jürg Utzinger, Jennifer Keiser, Marcel Tanner, Jacques Chollet
2009-07-14

Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening

Adam R Renslo, James H McKerrow
2008-06-19

Investigation of the redox behavior of ferroquine, a new antimalarial

Christophe Biot, Hervé Vezin
2008-11-20

Ferroquine, an ingenious antimalarial drug: thoughts on the mechanism of action

Faustine Dubar, Jamal Khalife, Christophe Biot
2007-05-01

Surgical pathology of schistosomiasis
2006-07

Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk
2006-09-23

Human schistosomiasis
2006-11-10

Antimalarial drugs inhibiting hemozoin (beta-hematin) formation: a mechanistic update

Vinay Choubey, Pallab Maity
2005-04-01

Selective estrogen receptor modulators in the ruthenocene series. Synthesis and biological behavior

Elizabeth A. Hillard, Gérard Jaouen, Pascal Pigeon, Anne Vessieres, Emmanuel Salomon, Siden Top, Michel Huché
2005-05-01

Insights into the mechanism of action of ferroquine. Relationship between physicochemical properties and antiplasmodial activity

Christophe Biot, Donatella Taramelli

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