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The Intratumoral Heterogeneity of Cancer Metabolism

author

Anne Le

published in: Advances in Experimental Medicine and Biology

date of publication: 2018-01-01

language: English

main subject: heterogeneity

Cites articles 46

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Phenotypic heterogeneity of disseminated tumour cells is preset by primary tumour hypoxic microenvironments

Georg Fluegen, David Entenberg, Vladislav V Verkhusha, John Condeelis, Jose J Bravo-Cordero
2017-05-01

Value of Intratumoral Metabolic Heterogeneity and Quantitative 18F-FDG PET/CT Parameters to Predict Prognosis in Patients With HPV-Positive Primary Oropharyngeal Squamous Cell Carcinoma

Arman Rahmim
2017-02-16

Intra-tumor heterogeneity from a cancer stem cell perspective

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2017-04-06

Intratumor Heterogeneity in Primary Kidney Cancer Revealed by Metabolic Profiling of Multiple Spatially Separated Samples within Tumors

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2016-03-04

Intratumoral heterogeneity identified at the epigenetic, genetic and transcriptional level in glioblastoma
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Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer

Joshua K Park, Shiyu Xia, Gregg L. Semenza, Justin Hanes, Jesse Alt, Barbara S Slusher
2016-11-11

WZB117 (2-Fluoro-6-(m-hydroxybenzoyloxy) Phenyl m-Hydroxybenzoate) Inhibits GLUT1-mediated Sugar Transport by Binding Reversibly at the Exofacial Sugar Binding Site
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Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth

Ubaldo E Martinez-Outschoorn, Michael P. Lisanti, Federica Sotgia
2014-02-04

Hypoxia signaling pathways in cancer metabolism: the importance of co-selecting interconnected physiological pathways

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PET/CT imaging in cancer: current applications and future directions
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Endothelial cell metabolism and tumour angiogenesis: glucose and glutamine as essential fuels and lactate as the driving force
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PKM2, a Central Point of Regulation in Cancer Metabolism

Jason De Melo
2013-08-01

Role of PFKFB3-driven glycolysis in vessel sprouting

Frans Schuit, Bart Ghesquière, Mieke Dewerchin, Inmaculada Segura, Jonathan C Welti, Ilaria Decimo, Maria Georgiadou, Susana Rocha, Brian W Wong, Anna Rita Cantelmo, Sebastian Munck, Francesco Bifari, Hiromi Imamura, Dirk Daelemans, Holger Gerhardt, Ramon Bartrons, Johan Hofkens, Peter Carmeliet, Ralph J DeBerardinis, Stefan Vinckier
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HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations

Gregg L. Semenza
2012-01-01

The origin of cancer stem cells
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Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells

Anne Le, Sminu Bose, Daniel C. Liebler, Chi V. Dang, Robbert J C Slebos, Barbara S Slusher
2012-02-29

Cancer cell differentiation heterogeneity and aggressive behavior in solid tumors
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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

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2-Deoxy-D-glucose treatment of endothelial cells induces autophagy by reactive oxygen species-mediated activation of the AMP-activated protein kinase
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Mithat Gönen, So Yeon Park, Kornelia Polyak, Franziska Michor
2010-01-19

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

Anne Le, Chi V. Dang, Gregg L. Semenza, Anirban Maitra
2010-07-30

Critical role for lactate dehydrogenase A in aerobic glycolysis that sustains pulmonary microvascular endothelial cell proliferation
2010-09-23

Balancing biosynthesis and bioenergetics: metabolic programs in oncogenesis
2010-10-27

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Zachary Schafer, Joan Brugge
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2009-12-21

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

Hagop Kantarjian, Marina Konopleva, Michael Andreeff, Ismael Samudio, Michael Fiegl, Borys Korchin, William Bornmann, Seshagiri R Duvvuri
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Tumor cell metabolism imaging

Article - wd:Q60628577

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