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Effect of Genetically Low 25-Hydroxyvitamin D on Mortality Risk: Mendelian Randomization Analysis in 3 Large European Cohorts

published in: Nutrients

date of publication: 2019-01-02

language: English

main subject: Individual participant data, Mendelian randomization

Cites articles 46

Date

Title

Authors

2018-01-09

Association between Vitamin D Genetic Risk Score and Cancer Risk in a Large Cohort of U.S. Women.

Julie E. Buring, Edward Giovannucci, Stephanie A Smith-Warner, JoAnn E. Manson, Paul Ridker, Daniel I Chasman, Lynda M Rose, Nancy R. Cook, Paulette D Chandler, Deirdre K Tobias, Howard D Sesso
2018-01-17

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels.

Marian Beekman, Joris Deelen, Marcus E Kleber, Alexis C. Wood, Peter K Joshi, James F. Wilson, Caroline Hayward, Fernando Rivadeneira, Leo-Pekka Lyytikäinen, M. Arfan Ikram, Alana Cavadino, Josée Dupuis, Paul F. O'Reilly, Ana M. Valdes, Karl Michaëlsson, Mika Kähönen, Martin den Heijer, Cassianne Robinson-Cohen, Jerome I Rotter, Claudia Langenberg, Claes Ohlsson, Terho Lehtimäki, Ching-Ti Liu, Kay-Tee Khaw, Mark McCarthy, Malcolm G. Dunlop, Evropi Theodoratou, Winfried März, Erik Ingelsson, Nicholas J. Wareham, Stephen B Kritchevsky, Eric Boerwinkle, Naveed Sattar, Stella Trompet, Ramachandran S. Vasan, David Karasik, Lars Lind, Mattias Lorentzon, Yongmei Liu, Demetrius Albanes, Bryan R Kestenbaum, Olli Raitakari, Marjo-Riitta Järvelin, Pamela L. Lutsey, J Wouter Jukema, Stephanie J. Weinstein, Luigi Ferrucci, M. Kyla Shea, Johan G. Eriksson, John Danesh, Stefan Pilz, L. Adrienne Cupples, Elizabeth A Streeten, Tim Spector, M. Carola Zillikens, Eline Slagboom, Nita G. Forouhi, Elina Hyppönen, Kurt K Lohman, André Uitterlinden, Douglas P. Kiel, Diana van Heemst, Linda Broer, Chris Power, Lisette de Groot, Christian Gieger, Harry Campbell, Susan M Farrington, Henry Völzke, Denise Houston, Adam S. Butterworth, Stephen S Rich, Thomas J. Wang, Eleni Sofianopoulou, Thomas E Gundersen, Jusheng Zheng, Liesbeth Vandenput, Nathalie van der Velde, Henri Wallaschofski, Ian H de Boer, Yanhua Zhou, Jiańan Luan, Anke W Enneman, Emmi Tikkanen, Erin D. Michos, Peter Kraft
2018-11-10

Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease

Julie E. Buring, Edward Giovannucci, JoAnn E. Manson, Walter C. Willett, Nancy R. Cook, William G Christen, VITAL Research Group, Shari S Bassuk, Samia Mora
2017-02-16

Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortium

Thor Aspelund, Winfried März, Gudny Eiriksdottir, Ragnar Joakimsen, Markus A. Busch, Maja-Lisa Løchen, Mary Frances Cotch, Elias F. Gudmundsson, Christa Scheidt-Nave, Tamara B. Harris, Ingeborg A Brouwer, Inger Njølstad, Henrik Schirmer, Vilmundur Gudnason, Giel Nijpels, Jacqueline M Dekker, Gert Mensink, Natasja M van Schoor, Tom Wilsgaard, Lars Rejnmark, Stefan Pilz, Paul Lips, Christopher T Sempos, Ellisiv Mathiesen, Marcus E Kleber, Martin R Grübler, Kevin D Cashman, Karin M A Swart, Rolf Jorde, Guri Grimnes, Andreas Tomaschitz, Diana Grove-Laugesen, Ramon Durazo-Arvizu, Zuzana Skrabakova, Kirsten G Dowling, Mairead Kiely, Esther van 't Riet, Femke Rutters, Joline W J Beulens
2017-03-01

Effect of Vitamin D and Calcium Supplementation on Cancer Incidence in Older Women: A Randomized Clinical Trial
2017-06-01

Effect of Monthly High-Dose Vitamin D Supplementation on Cardiovascular Disease in the Vitamin D Assessment Study : A Randomized Clinical Trial

Debbie Waayer, Kay-Tee Khaw, Carlos A. Camargo, Robert Scragg, Carlene Lawes
2017-05-12

Effect of vitamin D on all-cause mortality in heart failure (EVITA): a 3-year randomized clinical trial with 4000 IU vitamin D daily

Heiner K Berthold, Armin Zittermann, Stefan Pilz
2017-07-18

The Vitamin D Standardization Program (VDSP) Manual for Retrospective Laboratory Standardization of Serum 25-Hydroxyvitamin D Data

Stephen P J Brooks, Christopher T Sempos
2017-09-26

Serum 25-hydroxyvitamin D as a predictor of mortality and cardiovascular events: A 20-year study of a community-based cohort.

K Zhu, John P Walsh, Matthew Knuiman
2017-10-31

Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study.

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Vitamin D deficiency in Europe: pandemic?

Markus A. Busch, Gudny Eiriksdottir, Stefaan De Henauw, Jara Valtueña, Camilla T Damsgaard, George Moschonis, Mary Frances Cotch, Marcela Gonzalez-Gross, Christel Lamberg-Allardt, Luis Moreno, Christian Mølgaard, Yannis Manios, Jacqueline M Dekker, Giel Nijpels, Seppo Koskinen, Gail Goldberg, Natasja M van Schoor, Stefan Pilz, Paul Lips, Christopher T Sempos, Christina Mavrogianni, Kevin D Cashman, Kirsten G Dowling, Gert Mensink, Rolf Jorde
2016-09-14

Genetically Low Vitamin D Levels, Bone Mineral Density, and Bone Metabolism Markers: a Mendelian Randomisation Study
2016-04-09

Evidence for the vitamin D hypothesis: The NHANES III extended mortality follow-up

Charles B Eaton
2016-11-16

Genetically decreased vitamin D and risk of Alzheimer disease

John A Morris
2016-10-28

Associations between Serum Vitamin D and Genetic Variants in Vitamin D Pathways and Age-Related Macular Degeneration in the European Eye Study

Gareth Mckay, Ian S. Young, Usha Chakravarthy, Mati Rahu, Fotis Topouzis, Jesus Vioque
2015-03-12

Live longer with vitamin D?

Michael F. Holick
2015-05-06

Vitamin D as a Resilience Factor, Helpful for Survival of Potentially Fatal Conditions: A Hypothesis Emerging from Recent Findings of the ESTHER Cohort Study and the CHANCES Consortium

Hermann Brenner, Ben Schöttker
2015-04-01

No evidence that genetically reduced 25-hydroxyvitamin D is associated with increased risk of ischaemic heart disease or myocardial infarction: a Mendelian randomization study

Marianne Benn, Børge G. Nordestgaard, Shoaib Afzal
2015-11-18

State- and trait-dependent associations of vitamin-D with brain function during aging

Luigi Ferrucci, Madhav Thambisetty, Toshiko Tanaka
2014-02-01

In healthy adults, biological activity of vitamin D, as assessed by serum PTH, is largely independent of DBP concentrations.

Lisa Langsetmo
2014-01-10

Vitamin D supplementation for prevention of mortality in adults

Christian Gluud, Lise Lotte Gluud, Dimitrinka Nikolova, Jørn Wetterslev, Goran Bjelakovic, Marija Daković
2014-04-01

Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies

Clare Teresa Oliver-Williams, Laura Johnson, An Pan, Setor K Kunutsor, Dorairaj Prabhakaran, Oscar H Franco, Frank Hu
2014-01-28

Vitamin D concentration, obesity, and risk of diabetes: a mendelian randomisation study

Børge G. Nordestgaard, Shoaib Afzal, Stig Egil Bojesen, Peter Brøndum-Jacobsen
2014-01-24

The effect of vitamin D supplementation on skeletal, vascular, or cancer outcomes: a trial sequential meta-analysis

Mark Bolland, Ian Reid, Greg Gamble
2014-08

Meta-analysis of all-cause mortality according to serum 25-hydroxyvitamin D

William B. Grant, Edward Giovannucci, Robert P. Heaney
2014

Vitamin D and mortality: meta-analysis of individual participant data from a large consortium of cohort studies from Europe and the United States

Paolo Boffetta, Antonia Trichopoulou, Hermann Brenner, Ben Schöttker, Roman Topor-Madry, Abdonas Tamošiūnas, Růžena Kubínová, Laura Perna, Lisette de Groot, Inger Njølstad, Barbara Thorand, Wolfgang Rathmann, José Ordóñez-Mena, Anne Peasey, Edith Feskens, Maria F Hughes, Martin Bobak, Andrzej Pajak, Tom Wilsgaard, Ellisiv Mathiesen, Ellen Kampman, Martinette T Streppel, Rolf Jorde, Galatios Siganos, Frank Kee
2014-06-25

Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study

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2014-09-30

Association between circulating 25-hydroxyvitamin D and incident type 2 diabetes: a mendelian randomisation study

Claudia Langenberg, Fumiaki Imamura, Stephen Burgess, Nita G. Forouhi, Nicholas J. Wareham, Stephen J Sharp, Wei Zheng, Robert A Scott, InterAct Consortium
2014-11-18

Genetically low vitamin D concentrations and increased mortality: Mendelian randomisation analysis in three large cohorts

Børge G. Nordestgaard, Shoaib Afzal, Stig Egil Bojesen, Peter Brøndum-Jacobsen
2014-11-18

Vitamin D genes and mortality

Paul Welsh, Naveed Sattar
2013

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts

Luigi Ferrucci, Marika Kaakinen, Anneli Pouta, Anna-Liisa Hartikainen, Marjo-Riitta Järvelin, Terho Lehtimäki, Cyrus Cooper, Josée Dupuis, Winfried März, Veikko Salomaa, Olli Raitakari, Karl-Heinz Herzig, Elina Hyppönen, Hakan Melhus, Liisa Byberg, Jorma Viikari, Antti Jula, Erik Ingelsson, Evropi Theodoratou, Lina Zgaga, Liesbeth Vandenput, Marcus E Kleber, Willem H. Ouwehand, Malcolm G. Dunlop, John Whittaker, Karl Michaëlsson, Braxton D. Mitchell, Stephen B Kritchevsky, Claes Ohlsson, Aroon Hingorani, Mark McCarthy, Nicholas J. Wareham, Ruth J. Loos, Lars Lind, Mattias Lorentzon, Tim Frayling, Stefan Pilz, Laura M Yerges-Armstrong, Elizabeth A Streeten, Tim Spector, Reedik Mägi, Karani S. Vimaleswaran, Denise Houston, Andrew R Wood, Karen A Jameson, Nigel K Arden, Kurt K Lohman, Thomas J. Wang, Harry Campbell, Emmi Tikkanen
2013-03-28

Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality-a review of recent evidence

Michael F. Holick, William B. Grant, Paweł Płudowski, Yehuda Shoenfeld, Bruce W. Hollis, Stefan Pilz

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