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p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements

author

Paola Campomenosi

Paola Monti

Michael A Resnick

published in: Oncogene

date of publication: 2001-06-01

language: English

Cites articles 33

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2000-03-01

Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy

Alan Fersht
2000-08-01

Improving the detection of p53 mutations in breast cancer by use of the FASAY, a functional assay
2000-04-01

High frequency in esophageal cancers of p53 alterations inactivating the regulation of genes involved in cell cycle and apoptosis
2000-11-16

Surfing the p53 network

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1999-12-22

Prognostic significance ofp53 mutation in breast cancer: Frequent detection of non-missense mutations by yeast functional assay,Prognostic significance of p53 mutation in breast cancer: frequent detection of non-missense mutations by yeast functional assay

Anne Estreicher
1999-12-01

Pharmacological rescue of mutant p53 conformation and function
1999-06-01

Relationship between DNA methylation and mutational patterns induced by a sequence selective minor groove methylating agent

Paola Monti
1999-08-01

Increased apoptosis induction by 121F mutant p53

Anne Estreicher
1999-04-01

Novel p53 mutants selected in BRCA-associated tumours which dissociate transformation suppression from other wild-type p53 functions.
1999-01-01

Evolutionary conservation and somatic mutation hotspot maps of p53: correlation with p53 protein structural and functional features

Wojciech Makalowski
1998-03-01

Identification of human p53 mutations with differential effects on the bax and p21 promoters using functional assays in yeast

Sébastien Lenglet
1998-10-01

The complexity of p53 modulation: emerging patterns from divergent signals
1998-05-01

Ultraviolet-light induced p53 mutational spectrum in yeast is indistinguishable from p53 mutations in human skin cancer
1997-12-01

Heterogeneous p53 mutations in a Burkitt lymphoma from an AIDS patient with monoclonal c-myc and VDJ rearrangements
1997-03-01

Determining mutational fingerprints at the human p53 locus with a yeast functional assay: a new tool for molecular epidemiology

Paola Monti, Francesco Molina
1997-02-07

p53, the cellular gatekeeper for growth and division
1997-09-18

A model for p53-induced apoptosis

Bert Vogelstein, Kenneth W Kinzler
1997-09-01

Cell-cycle arrest versus cell death in cancer therapy

Kenneth W Kinzler, Bert Vogelstein
1997-01

Field cancerisation and polyclonal p53 mutation in the upper aero- digestive tract

Anne Estreicher
1996-07-01

Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

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1996-10-01

Regulation of mutant p53 temperature-sensitive DNA binding

Thierry Soussi
1996-05-01

p53: puzzle and paradigm
1996-09-01

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function
1996-02-01

Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant
1996-08-01

Structural aspects of the p53 protein in relation to gene evolution: a second look

Thierry Soussi
1995-09-01

TP53 mutations and breast cancer prognosis: particularly poor survival rates for cases with mutations in the zinc-binding domains

Charles Theillet, Anne-Lise Børresen-Dale
1995-04-01

A simple p53 functional assay for screening cell lines, blood, and tumors
1995-07-01

Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases
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Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations
1994-12-01

Transcriptional activation by p53 correlates with suppression of growth but not transformation.
1994-11-01

Mutation of conserved domain II alters the sequence specificity of DNA binding by the p53 protein
1994-08-01

Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation

Thierry Soussi

Article - wd:Q61988945

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