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Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis

autore

Matthew C. Fisher

Sayoki Mfinanga

Síle F Molloy

Thomas Harrison

William Hope

pubblicato in: Journal of Clinical Investigation

data di pubblicazione: 2019-01-28

lingua: inglese

argomento principale: Drug therapy, meningite, fluconazolo, cryptococcal meningitis

Cita articoli 54

Data

Titolo

Autori

2018-02-14

A systematic review of fluconazole resistance in clinical isolates of Cryptococcus species

Felix Bongomin, Rita O. Oladele, Sara Gago
2018-03-01

Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa.

Elvis Temfack, David Lalloo, Thomas Harrison, Robert Heyderman, Tihana Bicanic, Shabbar Jaffar, Newton Kalata, Angela Loyse, Charles van der Horst, Olivier Lortholary, Charles Kouanfack, Philip Bright, Síle F Molloy, John Bradley, Peter Mwaba, Sayoki Mfinanga, Mina C Hosseinipour, Joep J van Oosterhout
2018-06-25

Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia.

Judith Berman, Arnaldo Lopes Colombo
2018-11-05

Mixed Mycobacterium tuberculosis-Strain Infections Are Associated With Poor Treatment Outcomes Among Patients With Newly Diagnosed Tuberculosis, Independent of Pretreatment Heteroresistance

Robin M. Warren, David M Engelthaler
2017-01-17

Fluconazole 1200mg or 800mg for cryptococcal meningitis treatment in Ivory Coast
2017-04-03

A Population Genomics Approach to Assessing the Genetic Basis of Within-Host Microevolution Underlying Recurrent Cryptococcal Meningitis Infection

Matthew C. Fisher, Johanna Rhodes, Mathew A. Beale, Shichina Kannambath, Graeme Meintjes, Thomas Harrison, Tihana Bicanic, Joseph N. Jarvis
2017-03-07

Microevolution of Serial Clinical Isolates of Cryptococcus neoformans var. grubii and C. gattii

Christina A. Cuomo, Yuan Chen, Rhys A Farrer, John R Perfect, Anastasia P Litvintseva, Nelesh P Govender
2017-05-05

Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis

David W. Denning, David R. Boulware, Joseph N. Jarvis, Nelesh P Govender
2017-05-30

Mismatch Repair of DNA Replication Errors Contributes to Microevolution in the Pathogenic Fungus Cryptococcus neoformans

Surbhi Verma, Viplendra P S Shakya, Alexander Idnurm
2017-05-01

Fluconazole-Induced Ploidy Change in Cryptococcus neoformans Results from the Uncoupling of Cell Growth and Nuclear Division

Kaustuv Sanyal
2017-06-28

Heteroresistance and fungi

Gabriella F Ferreira, Daniel A Santos
2017-06-29

Cryptococcal meningitis: A neglected NTD?

Charles Kouanfack, Elvis Temfack, David R. Boulware, David W. Denning, Thomas Harrison, Tihana Bicanic, Shabbar Jaffar, Angela Loyse, Olivier Lortholary, Sayoki Mfinanga, Joseph N. Jarvis
2017-07-05

Tracing Genetic Exchange and Biogeography of Cryptococcus neoformans var. grubii at the Global Population Level

Ferry Hagen, Johanna Rhodes, Christopher A Desjardins, Mathew A. Beale, Anuradha Chowdhary, Daniel J. Lawson, Arnaldo Lopes Colombo, Wieland Meyer, Alexandre Alanio, Jo-Marie Vreulink, Joseph Heitman, John R Perfect, Tihana Bicanic, Thomas Harrison, Matthew C. Fisher, Christina A. Cuomo, David M Engelthaler, Anastasia P Litvintseva
2017-12-20

Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic.

Kate L Ormerod, Milos Tanurdzic, Benjamin L Schulz
2016-04-27

diskImageR: quantification of resistance and tolerance to antimicrobial drugs using disk diffusion assays

Judith Berman
2016-07-18

A Combination Fluorescence Assay Demonstrates Increased Efflux Pump Activity as a Resistance Mechanism in Azole-Resistant Vaginal Candida albicans Isolates

Somanon Bhattacharya, Theodore C White, Jack Sobel
2016-08-02

Heteroresistance to Fluconazole Is a Continuously Distributed Phenotype among Candida glabrata Clinical Strains Associated with In Vivo Persistence

Judith Berman
2016-12-01

Ploidy dynamics and evolvability in fungi

Judith Berman,
2015-01-01

Antimicrobial heteroresistance: an emerging field in need of clarity

Omar M El-Halfawy, Miguel A. Valvano
2015-10-13

Polyploid titan cells produce haploid and aneuploid progeny to promote stress adaptation

Judith Berman, Kate L Ormerod, James Fraser
2015-12-21

Cryptococcus: from environmental saprophyte to global pathogen

Robin C. May, Neil R H Stone, Tihana Bicanic
2014-03

A tetraploid intermediate precedes aneuploid formation in yeasts exposed to fluconazole

Judith Berman, Melanie Wellington, Yaakov Nahmias
2014-11-06

A prospective study of mortality from cryptococcal meningitis following treatment induction with 1200 mg oral fluconazole in Blantyre, Malawi

Katherine M Gaskell, Robert Heyderman, Thomas Harrison, David Lalloo, Derek J Sloan, Nicholas A Feasey, Camilla Rothe
2014-11-20

YMAP: a pipeline for visualization of copy number variation and loss of heterozygosity in eukaryotic pathogens

Judith Berman, Aviv Regev
2014-12-26

Impact of carbapenem heteroresistance among clinical isolates of invasive Escherichia coli in Chongqing, southwestern China

Shuangshuang Yang
2013-02-04

Ploidy variation as an adaptive mechanism in human pathogenic fungi

James Fraser, Carl A Morrow
2013-06-20

Flucytosine and cryptococcosis: time to urgently address the worldwide accessibility of a 50-year-old antifungal

Thomas Harrison, Olivier Lortholary
2013-07-08

Azole heteroresistance in Cryptococcus neoformans: emergence of resistant clones with chromosomal disomy in the mouse brain during fluconazole treatment
2013

A prospective longitudinal study of the clinical outcomes from cryptococcal meningitis following treatment induction with 800 mg oral fluconazole in Blantyre, Malawi

David Lalloo, Robert Heyderman, Nicholas A Feasey, Camilla Rothe, Joep J van Oosterhout
2012-04-27

Titan cells confer protection from phagocytosis in Cryptococcus neoformans infections
2011-07-26

Stress alters rates and types of loss of heterozygosity in Candida albicans

Judith Berman
2011-09-13

Wild-type MIC distributions and epidemiologic cutoff values for fluconazole, posaconazole, and voriconazole when testing Cryptococcus neoformans as determined by the CLSI broth microdilution method.

Daniel J. Diekema, Michael A. Pfaller, Mariana Castanheira, Shawn A Messer, Ronald N Jones

Articolo - wd:Q64229904

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