Victor Velculescu

1970 -

photo credits: Wikimedia Commons

country of citizenship: Romania

languages spoken, written or signed: Romanian

educated at: Stanford University

occupation: physician, oncologist

award received: Paul Marks Prize for Cancer Research

official website: www.hopkinsmedicine.org/profiles/results/directory/profile/8443494/victor-velculescu

Victor E. Velculescu (born August 16, 1970) is a Professor of Oncology and Co-Director of Cancer Biology at Johns Hopkins University School of Medicine. He is internationally known for his discoveries in genomics and cancer research. Source: Wikipedia (en)

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Articles 166

Date

Title

Authors

2021-07-21

Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers

Valsamo Anagnostou, Sarah Wheelan, Victor Velculescu, Jamie E Chaft, Shibin Zhou, Taha Merghoub, Srinivasan Yegnasubramanian, Hongkai Ji, Kellie N Smith, David R Jones, Bernard Park
2020-01-27

White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer

Alessandro Leal, Nicole van Grieken, Jamie E Medina, Valsamo Anagnostou, Daniel C Bruhm, Dick Johan van Spronsen, Laurens V Beerepoot, Edwin P M Jansen, Elma Klein Kranenbarg, Remond Fijneman, Victor Velculescu, Gerrit Meijer
2020-07-24

Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models

Hyoung Kim, Haineng Xu, Gordon B. Mills, Rugang Zhang, Victor Velculescu, Fiona Simpkins
2020-08-14

Genomic characterization of malignant progression in neoplastic pancreatic cysts

Michaël Noë, Marija Debeljak, Claudio Luchini, Aldo Scarpa, Giuseppe Zamboni, Seung-Mo Hong, Shinichi Yachida, Nobuyoshi Hiraoka, Anthony J Gill, Anne Hoorens, Nicholas J Roberts, Ralph H. Hruban, Rachel Karchin, Lodewijk A A Brosens, Victor Velculescu, Laura D Wood, Jordan M Winter, Robert B Scharpf, Violeta Beleva Guthrie, Vilmos Adleff, Jaswinder S Samra, Volkan Adsay, Jorge Albores-Saavedra, Benoit Terris, M Paola Castelli, Eniko Papp, Noushin Niknafs
2020-09-08

Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma

Jedd D Wolchok, Antoni Ribas, F Stephen Hodi, Victor Velculescu
2020-09-01

Neoadjuvant nivolumab plus ipilimumab in resectable non-small cell lung cancer

Joshua E Reuss, Jarushka Naidoo, Victor Velculescu, David R Jones
2020-09-19

Diagnostic strategies towards clinical implementation of liquid biopsy RAS/BRAF circulating tumor DNA analyses in patients with metastatic colorectal cancer

Karen Bolhuis, Victor Velculescu, Gerrit Meijer
2020-08-28

Inherited Rare, Deleterious Variants in ATM Increase Lung Adenocarcinoma Risk

Myvizhi Esai Selvan, Marjorie Zauderer, Victor Velculescu, Kenneth Offit
2020-01-13

Multimodal genomic features predict outcome of immune checkpoint blockade in non-small-cell lung cancer

Valsamo Anagnostou, Rachel Karchin, Victor Velculescu
2020-11-17

Integrative Tumor and Immune Cell Multi-omic Analyses Predict Response to Immune Checkpoint Blockade in Melanoma

Antoni Ribas, Victor Velculescu
2020-12-05

Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma

Antoni Ribas, F Stephen Hodi, Victor Velculescu
2019-03-06

Correction to: persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1

Bert Vogelstein, Kenneth W Kinzler, Victor Velculescu, Drew M Pardoll, Luis Alberto Diaz Jr, Kellie N Smith, Jennifer N Durham, Nickolas Papadopoulos, Brandon S Luber, Janis M Taube, Ada J Tam, Laveet K Aulakh, Franck Housseau, Nicolas J Llosa, Cynthia L Sears, Hongni Fan, Bjarne Bartlett, Nicholas Siegel, Tricia R Cottrell, Prerna Suri, Hok Yee Chan, Haidan Guo, Teniola Oke, Anas H Awan, Franco Verde, Ludmila Danilova, Valsamo Anagnostou, John-William Sidhom, Qingfeng Zhu, William Sharfman, Joanne Riemer, Kristen A Marrone, Jarushka Naidoo, Patrick F Forde, Sune Justesen, Julie R Brahmer
2019-02-11

Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1

Bert Vogelstein, Kenneth W Kinzler, Victor Velculescu, Drew M Pardoll, Luis Alberto Diaz Jr, Kellie N Smith, Jennifer N Durham, Nickolas Papadopoulos, Brandon S Luber, Janis M Taube, Ada J Tam, Laveet K Aulakh, Franck Housseau, Nicolas J Llosa, Cynthia L Sears, Hongni Fan, Bjarne Bartlett, Nicholas Siegel, Tricia R Cottrell, Prerna Suri, Hok Yee Chan, Haidan Guo, Teniola Oke, Anas H Awan, Franco Verde, Ludmila Danilova, Valsamo Anagnostou, John-William Sidhom, Qingfeng Zhu, William Sharfman, Joanne Riemer, Kristen A Marrone, Jarushka Naidoo, Patrick F Forde, Sune Justesen, Julie R Brahmer
2019-09-10

Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade

Jennifer N Durham, Bjarne Bartlett, Derek Murphy, Ellen L Verner, Erika Gedvilaite, Victor Velculescu
2019-01-24

Combined MEK and BCL-2/XL Inhibition Is Effective in High-Grade Serous Ovarian Cancer Patient-Derived Xenograft Models and BIM Levels Are Predictive of Responsiveness

Ioannis K Zervantonakis, Ronny Drapkin, Victor Velculescu, Gordon B. Mills, Joan Brugge
2019-11-21

Compartmental Analysis of T-cell Clonal Dynamics as a Function of Pathologic Response to Neoadjuvant PD-1 Blockade in Resectable Non-Small Cell Lung Cancer

Margueritta El Asmar, Jamie E Chaft, Victor Velculescu, Franck Housseau, Matthew D Hellmann, David R Jones
2019-12-23

High-Throughput Prediction of MHC Class I and II Neoantigens with MHCnuggets

Rohit Bhattacharya, Ashok Sivakumar, Lily Zheng, Ashton Omdahl, Maria Bonsack, Angelika B. Riemer, Victor Velculescu
2019-08-09

Genome-wide investigation of intragenic DNA methylation identifies ZMIZ1 gene as a prognostic marker in glioblastoma and multiple cancer types

Michael Lim, Peter C. Burger, Chetan Bettegowda, Victor Velculescu, Henry Brem
2019-05-29

Circulating Tumor DNA as a Clinical Test in Resected Pancreatic Cancer

Vincent P Groot, Ammar A Javed, Jun Yu, Christopher D Gocke, Elliot K. Fishman, Ralph H. Hruban, Victor Velculescu, Jin He, Matthew J Weiss, Christopher L Wolfgang, John L Cameron, James R Eshleman, Daniel A Laheru, Michael Goggins, Amol K Narang, Izaak Quintus Molenaar, Georgios Gemenetzis, Alina Hasanain, Hirohiko Kamiyama, Ming-Tseh Lin
2019-05-29

Genome-wide cell-free DNA fragmentation in patients with cancer

Alessandro Leal, Brian Woodward, Remond Fijneman, Claus Lindbjerg Andersen, Victor Velculescu, Gerrit Meijer
2019-08-30

Phase I Study of Rapid Alternation of Sunitinib and Regorafenib for the Treatment of Tyrosine Kinase Inhibitor Refractory Gastrointestinal Stromal Tumors

Alessandro Leal, Jillian Phallen, Andrew J Wagner, Victor Velculescu
2018-04-16

Neoadjuvant PD-1 Blockade in Resectable Lung Cancer

Matthew D Hellmann, Jiajia Zhang, Jedd D Wolchok, Victor Velculescu, David R Jones, Valerie W Rusch
2018-06-19

Ipilimumab plus nivolumab and DNA-repair defects in AR-V7-expressing metastatic prostate cancer.

Charles G. Drake, Victor Velculescu
2018-12-01

American Association for Cancer Research Project Genomics Evidence Neoplasia Information Exchange: From Inception to First Data Release and Beyond-Lessons Learned and Member Institutions' Perspectives

Justin Guinney, Victor Velculescu, Gerrit Meijer, Barrett J Rollins, Kenna Mills Shaw
2018-06-12

The Mutation-Associated Neoantigen Functional Expansion of Specific T Cells (MANAFEST) Assay: A Sensitive Platform for Monitoring Antitumor Immunity

Ludmila Danilova, Victor Velculescu
2018-12-12

Dynamics of Tumor and Immune Responses during Immune Checkpoint Blockade in Non-Small Cell Lung Cancer

Noushin Niknafs, Carolyn Hruban, Ashok Sivakumar, Lamia Rhymee, Peter Illei, James M. Isbell, Jennifer L Sauter, Robert B Scharpf, Jamie E Chaft, Matthew D Hellmann, Victor Velculescu
2018-12-20

Early Noninvasive Detection of Response to Targeted Therapy in Non-Small Cell Lung Cancer

Brian Woodward, Jamie E Medina, Christopher D Gocke, Parissa Keshavarzian, Robert B Scharpf, Victor Velculescu
2018-09-01

A machine learning approach for somatic mutation discovery

Derrick E Wood, Valsamo Anagnostou, Noushin Niknafs, Rachel Karchin, Eniko Papp, Luis Alberto Diaz Jr, Victor Velculescu, Samuel V Angiuoli, Mark Sausen, Sonya Parpart-Li, Christine L McCord, Andrew G Georgiadis
2018-06-14

BRAF Mutations Occur Infrequently in Ovarian Cancer but Suggest Responsiveness to BRAF and MEK Inhibition

Victor Velculescu
2018-11-01

Integrated Genomic, Epigenomic, and Expression Analyses of Ovarian Cancer Cell Lines

Ronny Drapkin, Stephen B. Baylin, Victor Velculescu
2017-08-01

Circulating Tumor DNA for Mutation Detection and Identification of Mechanisms of Resistance in Non-Small Cell Lung Cancer

Brian Woodward, Victor Velculescu
2017-10-23

High grade serous ovarian carcinomas originate in the fallopian tube

Ronny Drapkin, Sana Intidhar Labidi-Galy, Ayşe Ayhan, Victor Velculescu

Human - wd:Q7926425

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