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Defective Excitatory/Inhibitory Synaptic Balance and Increased Neuron Apoptosis in a Zebrafish Model of Dravet Syndrome

author

Alexandre Brenet

1994 -

Julie Somkhit

Nadia Soussi-Yanicostas

published in: Cells

date of publication: 2019-10-04

main subject: Dravet syndrome

Cites articles 38

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Title

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Drug repurposing for Dravet syndrome in scn1Lab-/- mutant zebrafish

Peter de Witte
2019-01-01

Network Properties Revealed during Multi-Scale Calcium Imaging of Seizure Activity in Zebrafish

Jing Liu, Scott C Baraban
2019-07-26

Tuning GABAergic Inhibition: Gephyrin Molecular Organization and Functions

Marilena Griguoli
2018-05-31

Non-canonical mTOR-Independent Role of DEPDC5 in Regulating GABAergic Network Development

Amrutha Swaminathan, Peter de Witte, Nadia Soussi-Yanicostas, Eric Samarut, Pierre Drapeau
2018-07-24

Excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity

Hai-Yan He, Hollis T. Cline
2018-10-15

γ-Aminobutyric acid receptor alpha 1 subunit loss of function causes genetic generalized epilepsy by impairing inhibitory network neurodevelopment

Eric Samarut, Amrutha Swaminathan, Nadia Soussi-Yanicostas, Patrick Cossette, Pierre Drapeau, Meijiang Liao
2017-01-10

Clemizole and modulators of serotonin signalling suppress seizures in Dravet syndrome

Kyla R Hamling, Aliesha Griffin, Scott C Baraban
2017-08-11

Alterations of apoptosis and autophagy in developing brain of rats with epilepsy: Changes in LC3, P62, Beclin-1 and Bcl-2 levels
2017-07-01

Behavioral Comorbidities and Drug Treatments in a Zebrafish scn1lab Model of Dravet Syndrome

Brian P Grone, Tiange Qu, Scott C Baraban
2016-01-29

Serotonergic Modulation as Effective Treatment for Dravet Syndrome in a Zebrafish Mutant Model

Ilse Smolders, Peter de Witte
2016-02-24

Plasticity of Hippocampal Excitatory-Inhibitory Balance: Missing the Synaptic Control in the Epileptic Brain
2016-03-01

Altered Glycolysis and Mitochondrial Respiration in a Zebrafish Model of Dravet Syndrome

Scott C Baraban, Matthew T Dinday
2016-12-20

Spatial patterning of excitatory and inhibitory neuropil territories during spinal circuit development.
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Animal models in epilepsy research: legacies and new directions

Scott C Baraban
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Pharmacological characterization of an antisense knockdown zebrafish model of Dravet syndrome: inhibition of epileptic seizures by the serotonin agonist fenfluramine

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Synaptic inhibition and γ-aminobutyric acid in the mammalian central nervous system
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Gene-specific differential response to anti-apoptotic therapies in zebrafish models of ocular coloboma

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Scn1a missense mutation causes limbic hyperexcitability and vulnerability to experimental febrile seizures
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Article - wd:Q90567767

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