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NTRK gene rearrangements are highly enriched in MLH1/PMS2 deficient, BRAF wild-type colorectal carcinomas-a study of 4569 cases

author

Tamara Fraser

Mahsa Ahadi

Talia Fuchs

Anthony J Gill

published in: Modern Pathology

date of publication: 2019-12-02

Cites articles 28

Date

Title

Authors

2020-02-01

Colonic Adenocarcinomas Harboring NTRK Fusion Genes: A Clinicopathologic and Molecular Genetic Study of 16 Cases and Review of the Literature

Bartosz Wasąg, Ewa Izycka-Swieszewska, Markku Miettinen, Jerzy Lasota, Wojciech Biernat, Stanisław Góźdź, Agnieszka Hałoń, Krzysztof Okon, Caj Haglund, Maciej Kaczorowski, Rafał Pęksa, Vincenzo Canzonieri, Piotr Waloszczyk, Małgorzata Chłopek, Artur Kowalik, Arndt Hartmann, Michał Pyzlak, Joanna Szpor, Justyna Szumiło, Janusz Ryś
2019-05-09

Testing algorithm for identification of patients with TRK fusion cancer

Frédérique Penault-Llorca
2019-08-27

Is secretory breast carcinoma underdiagnosed? In the era of targeted therapy should there be a low threshold to screen for NTRK immunohistochemistry in triple negative breast cancers?
2019-08-02

NTRK fusion detection across multiple assays and 33,997 cases: diagnostic implications and pitfalls

Ahmet Zehir, Alexander Drilon, David M Hyman, Denise Frosina
2019-02-01

Larotrectinib in adult patients with solid tumours: a multi-centre, open-label, phase I dose-escalation study
2019-01-14

Colorectal Carcinomas Containing Hypermethylated MLH1 Promoter and Wild-Type BRAF/KRAS Are Enriched for Targetable Kinase Fusions

Ahmet Zehir, Liying Zhang, Donna Wong, Alexander Drilon, Leonard B. Saltz, Alison M Schram, Jaclyn F Hechtman, Zsofia Stadler
2019-03-06

Australasian Gastrointestinal Pathology Society (AGPS) consensus guidelines for universal defective mismatch repair testing in colorectal carcinoma
2019-09-20

Negative Hyperselection of Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer Who Received Panitumumab-Based Maintenance Therapy

Lorenza Rimassa, Adele Busico, Giovanni Fucà
2019-05-16

Immunohistochemistry with a pan-TRK antibody distinguishes secretory carcinoma of the salivary gland from acinic cell carcinoma

Yin Pun Hung, Jason L. Hornick
2018-12-01

NTRK fusion-positive cancers and TRK inhibitor therapy

Alexander Drilon
2018-08-31

Molecular characterization of cancers with NTRK gene fusions

Semir Vranic
2018-02-01

Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children

Wafik El-Deiry, Jaclyn F Hechtman, Kevin T Ebata, David M Hyman, Ryma Benayed, Brian B Tuch, Alexander Drilon, Ramamoorthy Nagasubramanian
2018-09-12

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Frank Bray
2018-12-14

Implementing a comprehensive translational oncology platform: from molecular testing to actionability

Zahi I Mitri, Gordon B. Mills, Joe W Gray
2018-06-07

Basket trial of TRK inhibitors demonstrates efficacy in TRK fusion-positive cancers.
2017-07-17

Pan-Trk Immunohistochemistry Is an Efficient and Reliable Screen for the Detection of NTRK Fusions.

Marc Ladanyi, Denise Frosina, David S Klimstra
2017-09-25

Negative hyper-selection of metastatic colorectal cancer patients for anti-EGFR monoclonal antibodies: the PRESSING case-control study.

Federica Perrone, Chiara Cremolini, Federica Morano, Annunziata Gloghini, Adele Busico, Giovanni Fucà, Alfredo Falcone, Filippo Pietrantonio
2017-12-01

ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer

Filippo Pietrantonio, Federica Di Nicolantonio, Andrea Sartore-Bianchi, Jaclyn F Hechtman, Giovanni Fucà, Federica Morano, Chiara Cremolini, Alberto Bardelli, Filippo de Braud
2016-03-18

NTRK gene fusions as novel targets of cancer therapy across multiple tumour types

Andrea Sartore-Bianchi, A Amatu, Salvatore Siena
2016-10-01

MLH1-deficient Colorectal Carcinoma With Wild-type BRAF and MLH1 Promoter Hypermethylation Harbor KRAS Mutations and Arise From Conventional Adenomas

Lama Farchoukh
2015-01

TRKing down an old oncogene in a new era of targeted therapy

Robert C Doebele, Aria Vaishnavi
2015-12-18

Congenital mesoblastic nephroma: a study of 19 cases using immunohistochemistry and ETV6-NTRK3 fusion gene rearrangement
2015-12-01

Durable Clinical Response to Entrectinib in NTRK1-Rearranged Non-Small Cell Lung Cancer

Zongli Zheng, Stephen V Liu, Daniel B Costa
2015-05-19

Chromosomal rearrangements involving the NTRK1 gene in colorectal carcinoma

Rosine Guimbaud
2015-11-12

Sensitivity to Entrectinib Associated With a Novel LMNA-NTRK1 Gene Fusion in Metastatic Colorectal Cancer

Andrea Sartore-Bianchi, A Amatu, Emanuele Valtorta, Silvio Marco Veronese, Angelo Vanzulli, Alberto Bardelli, Salvatore Siena
2014-06-12

The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition

Marco A. Pierotti, Andrea Sartore-Bianchi, Salvatore Siena, Silvio Marco Veronese, Marcello Gambacorta
2013-10-01

BRAFV600E immunohistochemistry facilitates universal screening of colorectal cancers for Lynch syndrome

Andreas von Deimling, John Hopper, David Capper, Aung Ko Win, Christophe Rosty
2013-10-25

BRAFV600E immunohistochemistry in conjunction with mismatch repair status predicts survival in patients with colorectal cancer

Anthony J Gill

Article - wd:Q91620740

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