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Olfactomedin 4 (OLFM4) expression is associated with nodal metastases in esophageal adenocarcinoma

author

Lucia Suzuki

Leendert Looijenga

published in: PLOS One

date of publication: 2019-07-08

Cites articles 40

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The clinical significance and biological function of olfactomedin 4 in triple negative breast cancer
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Loss of OLFM4 promotes tumor migration through inducing interleukin-8 expression and predicts lymph node metastasis in early gastric cancer
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Olfactomedin 4 deletion induces colon adenocarcinoma in Apc(Min/+) mice
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ACG Clinical Guideline: Diagnosis and Management of Barrett's Esophagus

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Epigenetic silencing of olfactomedin-4 enhances gastric cancer cell invasion via activation of focal adhesion kinase signaling
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Olfactomedin-related proteins 4 (OLFM4) expression is involved in early gastric carcinogenesis and of prognostic significance in advanced gastric cancer
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Oestrogen receptor-mediated expression of Olfactomedin 4 regulates the progression of endometrial adenocarcinoma
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Deletion of the olfactomedin 4 gene is associated with progression of human prostate cancer

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OLFM4 is associated with lymph node metastasis and poor prognosis in patients with gastric cancer.
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Olfactomedin 4 suppresses prostate cancer cell growth and metastasis via negative interaction with cathepsin D and SDF-1.
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Olfactomedin 4 (GW112, hGC-1) is an independent prognostic marker for survival in patients with colorectal cancer

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Stem cell marker olfactomedin 4: critical appraisal of its characteristics and role in tumorigenesis
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Up regulation of GW112 Gene by NF kappaB promotes an antiapoptotic property in gastric cancer cells.
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OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells

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Article - wd:Q91709853

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