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BRAF in the cross-hairs

author

Mark Geyer

published in: Expert Review of Hematology

date of publication: 2019-02-26

language: English

Cites articles 69

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Title

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2018-11-01

Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer
2018-10-19

Targeting MEK in vemurafenib-resistant hairy cell leukemia

Grace Collord, Daniel J. Hodson
2018-08

Moxetumomab pasudotox in relapsed/refractory hairy cell leukemia

Douglas E Gladstone, Mirjana Gotic, Bjørn Tore Gjertsen, Farhad Ravandi, Francis Giles, Claire E. Dearden, Pier Luigi Zinzani, Andrzej Hellmann, Tadeusz Robak, Giuseppe Saglio, Wyndham H. Wilson
2018-06-28

Clinicopathologic and molecular features in hairy cell leukemia-variant: single institutional experience

Joseph D. Khoury, L Jeffrey Medeiros
2017-12-15

First-in-Class ERK1/2 Inhibitor Ulixertinib (BVD-523) in Patients with MAPK Mutant Advanced Solid Tumors: Results of a Phase I Dose-Escalation and Expansion Study.

Keith Flaherty, Mario Sznol, Filip Janku, Antoni Ribas, Elizabeth I Buchbinder
2017-08-11

Genomic analysis of hairy cell leukemia identifies novel recurrent genetic alterations

Omar Abdel-Wahab, Torsten Haferlach, Thorsten Zenz, Martin S. Tallman
2017-03-01

Vemurafenib in metastatic melanoma patients with brain metastases: an open-label, single-arm, phase 2, multicentre study

Michele Maio, Grant McArthur, Ana Arance, Claus Garbe, Richard F. Kefford, Christian U Blank
2016-11-30

Consensus guidelines for the diagnosis and management of patients with classic hairy cell leukemia

Pier Luigi Zinzani, Anthony Ho, Alessandro Gozzetti, Francesco Forconi, Constantine S. Tam, Brunangelo Falini, Farhad Ravandi, Thorsten Zenz, Daniel Catovsky, Claire E. Dearden, Monica Else, Martin S. Tallman, Tadeusz Robak, Timothy G. Call, Clive S Zent, Emili Montserrat
2016-05-31

Detection of activating MAP2K1 mutations in atypical hairy cell leukemia and hairy cell leukemia variant

Elizabeth Morgan
2016-04-27

Response of relapsed central nervous system hairy cell leukemia to vemurafenib
2016-03-03

BRAF inhibition in hairy cell leukemia with low-dose vemurafenib

Christof von Kalle, Wilko Weichert, Tilman Brummer, Clemens-Martin Wendtner, Torsten Haferlach, Thorsten Zenz, Michael Hallek, Claire E. Dearden
2015-10-29

Targeting Mutant BRAF in Relapsed or Refractory Hairy-Cell Leukemia

Eunhee Kim, Francesco Zaja, Mario E Lacouture, Brunangelo Falini, Robin Foà, Martin S. Tallman, Pier Luigi Zinzani, Stefano A Pileri, Alessandro Rambaldi
2015-06-11

Recurrent CDKN1B (p27) mutations in hairy cell leukemia

Wolfgang Huber, Christof von Kalle, Barbara Hutter, Benedikt Brors, Manja Meggendorfer, Torsten Haferlach, Thorsten Zenz, Claire E. Dearden, Monica Else, Estella Matutes
2015-01-01

Cotreatment of hairy cell leukemia and melanoma with the BRAF inhibitor dabrafenib

James S Blachly
2014-12-26

Successful re-treatment of a relapsed V600E mutated HCL patient with low-dose vemurafenib

Guillaume Robert, Paul Hofman, Patrick Auberger
2014-12-05

BRAF inhibitors reverse the unique molecular signature and phenotype of hairy cell leukemia and exert potent antileukemic activity

Gianluca Schiavoni, Paolo Sportoletti, Brunangelo Falini, Ludger Klein-Hitpass
2014-11-19

Quantitative cell-free circulating BRAFV600E mutation analysis by use of droplet digital PCR in the follow-up of patients with melanoma being treated with BRAF inhibitors

José Luis Pérez-Gracia
2014-11-13

Combined vemurafenib and cobimetinib in BRAF-mutated melanoma

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2014-09-29

Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma

Caroline Robert, Jean-Jacques Grob, Dirk Schadendorf, Keith Flaherty, Daniil Stroyakovskiy, Ana Arance, Virginia Ferraresi, Evgeny V Levchenko, Igor N. Bondarenko, Jochen Utikal, Georgina V. Long, Filippo de Braud, Antoni Ribas, Axel Hauschild
2014-05-01

Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia

Julie Teruya-Feldstein, Eunhee Kim, Omar Abdel-Wahab, Martin S. Tallman
2014-01-15

Differential activity of MEK and ERK inhibitors in BRAF inhibitor resistant melanoma

Georgina V. Long, Richard F. Kefford, Helen Rizos, Gulietta M Pupo, Matteo Carlino, Carina Fung, Branka Mijatov, Kavitha Gowrishankar, Stephanie Snoyman
2014-01-16

Alternative BRAF mutations in BRAF V600E-negative hairy cell leukaemias

Andreas Rosenwald
2014-03-20

Obinutuzumab plus Chlorambucil in Patients with CLL and Coexisting Conditions

Hartmut Döhner, Michael Hallek, Barbara Eichhorst, Stephan Stilgenbauer
2013-12-14

Successful vemurafenib salvage treatment in a patient with primary refractory hairy cell leukemia and pulmonary aspergillosis

Tobias Wengenmayer
2013-11-17

High prevalence of MAP2K1 mutations in variant and IGHV4-34-expressing hairy-cell leukemias

Joshua J Waterfall, Sean Davis
2013-06-03

Rapid response to vemurafenib in a heavily pretreated patient with hairy cell leukemia and a BRAF mutation

Razelle Kurzrock
2013-05-20

Continued response off treatment after BRAF inhibition in refractory hairy cell leukemia.

Boyan K Garvalov, Christof von Kalle, Till Acker, David Capper, Thorsten Zenz
2013-04-24

Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors

Rumin Zhang
2013-03-01

Analysis of dermatologic events in vemurafenib-treated patients with melanoma

Caroline Robert, Dirk Schadendorf, Axel Hauschild
2013-01-08

Low-dose vemurafenib induces complete remission in a case of hairy-cell leukemia with a V600E mutation

Robert Ballotti, Patrick Auberger, Guillaume Robert
2012-12-29

Rapid response of biallelic BRAF V600E mutated hairy cell leukaemia to low dose vemurafenib.

Thorsten Zenz
2012-11-07

Progression of RAS-mutant leukemia during RAF inhibitor treatment

Omar Abdel-Wahab, Jedd D Wolchok

Article - wd:Q91719232

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