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Exploratory locomotion, a predictor of addiction vulnerability, is oligogenic in rats selected for this phenotype

Autor

Huda Akil

1945 -

veröffentlicht in: Proceedings of the National Academy of Sciences

Erscheinungsdatum: 2019-06-10

Zitiert Artikel 47

Datum

Titel

Autor

2017-06-01

An Expanded View of Complex Traits: From Polygenic to Omnigenic

Yang I Li, Jonathan K. Pritchard
2016-08-17

Analysis of protein-coding genetic variation in 60,706 humans

Michael Boehnke, Sekar Kathiresan, Jaakko Tuomilehto, Markku Laakso, Karol Estrada, Aarno Palotie, Taru Tukiainen, Danish Saleheen, Gad Getz, Roberto Elosua, Adam Kiezun, Joanne Berghout, Pradeep Natarajan, James Ware, Hong-Hee Won, Douglas M. Ruderfer, Hugh Christian Watkins, Kaitlin E Samocha, Dongmei Yu, Eric Minikel, Christina M. Hultman, Mark Joseph Daly, Stacey Gabriel, Steven McCarroll, Dermot McGovern, Patrick F. Sullivan, James G. Wilson, Pamela Sklar, John Danesh, Lorena Orozco, Benjamin M. Neale, Valentin Ruano Rubio, Eric Banks, Laura D. Gauthier, Namrata Gupta, Grace Tiao, Jeremiah M Scharf, Diego Ardissino, David Altshuler, Gina M Peloso, Konrad J. Karczewski, Timothy R Fennell, Anne H O'Donnell-Luria, David N. Cooper, Daniel P Howrigan, Mark McCarthy, Shaun M Purcell, Daniel G. MacArthur, Mark DePristo, Monkol Lek, Jason Flannick, Jack A Kosmicki, Menachem Fromer, Mitja Kurki, Ami Levy Moonshine, Khalid Shakir, Christine Stevens, Ruth McPherson, Ryan Poplin
2016-04-25

Genetic background and epigenetic modifications in the core of the nucleus accumbens predict addiction-like behavior in a rat model

Maria Waselus, Huda Akil
2015-11-17

Addictions Neuroclinical Assessment: A Neuroscience-Based Framework for Addictive Disorders

David Goldman, George Koob
2015-01-01

The contribution of additive genetic variation to personality variation: heritability of personality.

Ned A. Dochtermann, Andrew Sih
2014-08-14

High locomotor reactivity to novelty is associated with an increased propensity to choose saccharin over cocaine: new insights into the vulnerability to addiction

David Belin
2014-04-17

Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid β generation
2014-03-01

ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample

Joel Gelernter, Laura Almasy, Hong-Wen Deng
2013-09-30

Loss of metabotropic glutamate receptor 2 escalates alcohol consumption

David Goldman, Meghan Flanigan, Howard J Edenberg
2013-07-18

Large-scale gene function analysis with the PANTHER classification system

Paul D Thomas
2012-12

Transcriptional mechanisms of drug addiction

Eric J. Nestler
2012

GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats

David Goldman, Deborah Mash
2011-10-18

Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster

Marcella Rietschel, Sven Cichon, Manuel Mattheisen, Marcus Ising, Bertram Müller-Myhsok, Michael Steffens, Per Hoffmann, Stefan Herms, Markus M Nöthen, Falk Kiefer, Jens Treutlein, Monika Ridinger, Norbert Wodarz, Rainald Mössner, Norbert Dahmen, Christine Schmäl, Susanne Lucae
2011-04-17

A Drosophila model for alcohol reward

Karla Kaun
2011-04-04

Substance-specific and shared transcription and epigenetic changes in the human hippocampus chronically exposed to cocaine and alcohol

David Goldman, Deborah Mash
2010-07-01

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

Gary D. Bader, Quaid D Morris, Jason Montojo, David Warde-Farley
2010-01-01

Impact of cocaine on adult hippocampal neurogenesis in an animal model of differential propensity to drug abuse

M. Julia García-Fuster
2010-01-01

An animal model of genetic vulnerability to behavioral disinhibition and responsiveness to reward-related cues: implications for addiction

Paul E. M. Phillips, Huda Akil
2010-01

Neurocircuitry of addiction

George Koob, Nora D. Volkow
2009-12-01

Copy number and sequence variants implicate APBA2 as an autism candidate gene.

William B. Dobyns
2009-05-01

X11-like protein deficiency is associated with impaired conflict resolution in mice

Yoshitake Sano, Shigeyoshi Itohara
2009-05-01

Interaction of Mint2 with TrkA is involved in regulation of nerve growth factor-induced neurite outgrowth

Zhao-Huan Zhang
2008-10-01

Review. Neurogenetic studies of alcohol addiction
2008-06-06

High impulsivity predicts the switch to compulsive cocaine-taking

Barry Everitt, David Belin, Trevor W. Robbins
2008-05-12

Addictions biology: haplotype-based analysis for 130 candidate genes on a single array

David Goldman, Joel Gelernter
2008-04

Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking

Vincent Mooser, Federica Tozzi, Clyde Francks
2008-02-01

Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia

George Kirov, Hans-Hilger Ropers, Reinhard Ullmann, Wei Chen, Michael C O'Donovan
2007-12-17

Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex

Elaine M Taylor
2006-06-01

Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction

Jean Logan, Joanna Fowler, Nora D. Volkow, Gene-Jack Wang, Frank Telang, Millard Jayne, Anna-Rose Childress
2006-09-01

Selective breeding for divergence in novelty-seeking traits: heritability and enrichment in spontaneous anxiety-related behaviors

John D Stead, Huda Akil
2005-10-01

Haplotype-based linkage of tryptophan hydroxylase 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populations.

Robert H. Lipsky, David Goldman
2005-07-01

The genetics of addictions: uncovering the genes

David Goldman

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