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ATM Serine/Threonine Kinase and its Role in Pancreatic Risk

diterbitkan dalam: Genes

tanggal publikasi: 2020-01-17

subyek utama: Reparasi DNA, pancreatic neoplasm, pancreatic ductal carcinoma

Cites articles 61

Date

Judul

Pengarang

2019-11-01

ATM Dysfunction in Pancreatic Adenocarcinoma and Associated Therapeutic Implications

Christopher W Schultz
2019-07-08

Histomorphology of pancreatic cancer in patients with inherited ATM serine/threonine kinase pathogenic variants

Nicholas J Roberts, Michael Goggins, Ralph H. Hruban, Matthew J Weiss, Christopher L Wolfgang, John L Cameron, David S Klimstra, Alison P Klein, Randall E Brand, Aatur D Singhi, Marty Makary, Danielle Hutchings, Michael Skaro
2019-06-02

Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer

Giampaolo Tortora
2019-08-01

Germline-focussed analysis of tumour-only sequencing: recommendations from the ESMO Precision Medicine Working Group
2019-03-18

Deleterious Germline Mutations Are a Risk Factor for Neoplastic Progression Among High-Risk Individuals Undergoing Pancreatic Surveillance

Toshiya Abe, Ralph H. Hruban
2019-03-01

Pancreatic Adenocarcinoma, Version 1.2019

Eileen M. O'Reilly, Brian M. Wolpin, Ellen F. Binder
2019-03-02

Real-Time Targeted Genome Profile Analysis of Pancreatic Ductal Adenocarcinomas Identifies Genetic Alterations That Might Be Targeted With Existing Drugs or Used as Biomarkers

Samuel J Klempner, Anirban Maitra, Amer H Zureikat
2019-02-01

Prevalence of Germline Mutations Associated With Cancer Risk in Patients With Intraductal Papillary Mucinous Neoplasms

Nicholas J Roberts, Ralph H. Hruban
2018-07-25

Multigene Hereditary Cancer Panels Reveal High-Risk Pancreatic Cancer Susceptibility Genes

Fergus J. Couch, David Goldgar
2018-09

Genetic Alterations of Periampullary and Pancreatic Ductal Adenocarcinoma: An Overview
2018-08-01

Prospective study of germline genetic testing in incident cases of pancreatic adenocarcinoma

Erkut Borazancı, Virginia Speare, Beth Dudley, Mary Linton B Peters, Herbert J. Zeh, III, Melissa E Hogg, Amer H Zureikat
2018-07-02

Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer

Shuji Ogino, Charles S. Fuchs, William C Hahn, Brian M. Wolpin
2018-06-01

Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer

Pashtoon Murtaza Kasi, Fergus J. Couch, Kari G Rabe, Gloria M Petersen
2018-04-30

Clinical significance of pancreatic intraepithelial neoplasia in resectable pancreatic cancer on survivals

Young-Dong Yu
2018-04-17

Morphology and genomic hallmarks of breast tumours developed by ATM deleterious variant carriers.

Fabienne Lesueur, Dominique Stoppa-Lyonnet, Anne-Laure Renault, Sylvain Baulande, Georgia Chenevix-Trench, Jacques-Olivier Bay, Anne Vincent-Salomon
2018-10-01

Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms

Maeve Lowery, Christine A Iacobuzio-Donahue, Kenneth Offit, David S Klimstra, Gokce Askan, Zsofia Stadler
2018-01-04

Cancer statistics, 2018.

Ahmedin Jemal
2017-09-11

ATM-deficiency increases genomic instability and metastatic potential in a mouse model of pancreatic cancer

Yiannis Drosos
2017-09-01

Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing

Philip W. Kantoff, Vignesh Ravichandran, Ronak H Shah, Maeve Lowery, Eileen M. O'Reilly, Kenneth Offit, David S Klimstra, Zsofia Stadler
2017-08-08

ATM Deficiency Generating Genomic Instability Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Therapy-Induced DNA Damage

Dietrich A. Ruess, Hana Algül, Laura Gieldon, Pierre-Olivier Frappart
2017-08-02

Deleterious Germline Mutations in Patients With Apparently Sporadic Pancreatic Adenocarcinoma

Nicholas J Roberts, Michael Goggins, Ralph H. Hruban, Matthew J Weiss, Christopher L Wolfgang, Alison P Klein, Michael Borges, Aaron Brant, Masaya Suenaga, Shahriar Fesharakizadeh, Jose Alejandro Navarro Almario, Madeline Ford, Anne Macgregor-Das, Christy Cho
2017-07-20

Prevalence of germ-line mutations in cancer genes among pancreatic cancer patients with a positive family history.

Kari G Rabe, Gloria M Petersen
2017-04-28

Susceptibility of ATM-deficient pancreatic cancer cells to radiation

Michael Ayars, Michael Goggins
2017-06-01

Association of Distinct Mutational Signatures With Correlates of Increased Immune Activity in Pancreatic Ductal Adenocarcinoma

John P Neoptolemos, Bradly Wouters, John McPherson, David Hedley, Lincoln Stein, Markus Büchler, Steven Garcia, Gloria M Petersen, Michael A. Hollingsworth, Ludmil B. Alexandrov, Robert E Denroche, Malcolm Moore, Lee Timms, Michelle Chan-Seng-Yue, Faiyaz Notta, Bo Gun Jang, Ilinca M Lungu, Michael H Roehrl, Treasa McPherson, Iris Selander
2016-10-06

Germline mutations in Japanese familial pancreatic cancer patients

Akihiro Ohmoto, Toru Furukawa, Ralph H. Hruban
2016-07-23

Multiple rare variants in high-risk pancreatic cancer-related genes may increase risk for pancreatic cancer in a subset of patients with and without germline CDKN2A mutations

William Bruno, Lorenza Pastorino, Giovanna Bianchi-Scarrà, Rainer Tuominen, Håkan Olsson, Paola Ghiorzo, Maria Teresa Landi, Stephen Chanock
2016-07-13

ATM Mutations in Cancer: Therapeutic Implications

Razelle Kurzrock
2016-04-25

Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert Centers.

Henricus Franciscus Antonius Vasen, Carmen Guillen Ponce, Enrique Vazquez-Sequeiros, Irene Esposito, Günter Klöppel, Hans Morreau
2015-12-09

Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer

Bert Vogelstein, Nicholas J Roberts, Sara H Olson, Kenneth W Kinzler, Christine A Iacobuzio-Donahue, Michael Goggins, Ralph H. Hruban, Steven Garcia, Mehdi Pirooznia, Christopher L Wolfgang, Kari G Rabe, Gloria M Petersen, Ann G Schwartz, James R Eshleman, Alison P Klein, Laura D Wood, Randall E Brand, Jennifer E Axilbund, Rachel Karchin, Nickolas Papadopoulos, Sapna Syngal, Noushin Niknafs, Christopher Douville, Alexis L Norris, Melissa L Bondy, George Zogopoulos, Michele L Cote, Melissa Kramer, W. Richard McCombie, Jennifer Parla, James B Potash, Andrew D Rhim, Peter P Zandi, Fernando S Goes, K Wyatt McMahon, Alvin P Makohon-Moore, Anil K Rustgi
2015-10-19

Prevalence of Pathogenic Mutations in Cancer Predisposition Genes among Pancreatic Cancer Patients

Steven N. Hart, William Bamlet, Raymond Moore, Fergus J. Couch, Gloria M Petersen
2015-07-29

Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition

Qiong Lin, Thomas Seufferlein, Guido von Figura
2015-05-27

Reliable Detection of Somatic Mutations in Fine Needle Aspirates of Pancreatic Cancer With Next-generation Sequencing: Implications for Surgical Management

Mouen A Khashab, Christine A Iacobuzio-Donahue, Ralph H. Hruban, Matthew J Weiss, Christopher L Wolfgang, John L Cameron, Daniel A Laheru, Avani S Dholakia, María Valero de Vicente, Anne Marie O'Broin-Lennon

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