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A protein assembly mediates Xist localization and gene silencing

Autor

Amy Pandya-Jones

Jacques Serizay

Arturo Alvarez-Buylla

Bernadett Papp

Heinrich Leonhardt

Douglas L Black

Kathrin Plath

Mitchell Guttman

veröffentlicht in: Nature

Erscheinungsdatum: 2020-09-09

Hauptthema: Gen-Silencing

Zitiert Artikel 46

Datum

Titel

Autor

2019-11-21

The liquid nucleome - phase transitions in the nucleus at a glance

Amy R Strom, Clifford Brangwynne
2019-02-14

Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis

Basant K Patel
2019-04-24

N-terminal sequences in matrin 3 mediate phase separation into droplet-like structures that recruit TDP43 variants lacking RNA binding elements
2018-09-26

X-Chromosome Inactivation: A Crossroads Between Chromosome Architecture and Gene Regulation

Rafael Galupa, Edith Heard
2017-12-01

hnRNPK Recruits PCGF3/5-PRC1 to the Xist RNA B-Repeat to Establish Polycomb-Mediated Chromosomal Silencing

Tatyana Nesterova, Guifeng Wei, Alfredo Castelló, Neil Brockdorff, Greta Pintacuda, Burcu Anil-Kirmizitas
2017-02-22

Biomolecular condensates: organizers of cellular biochemistry
2017-05-25

The nuclear matrix protein CIZ1 facilitates localization of Xist RNA to the inactive X-chromosome territory

Tatyana Nesterova, Emma R Stewart, Heather Coker, Rosemary H.C. Wilson, Neil Brockdorff, Justin F Ainscough, Dawn Coverley, Jonathan Godwin, Greta Pintacuda
2017-09-18

Repeat E anchors Xist RNA to the inactive X chromosomal compartment through CDKN1A-interacting protein (CIZ1).

Hongjae Sunwoo, John E Froberg, Jeannie T. Lee
2017-04-13

Quantitative 3D structured illumination microscopy of nuclear structures

Felix Kraus, Ezequiel Miron, Justin Demmerle, Lothar Schermelleh, Yolanda Markaki
2017-01-19

Cooperative Binding of Transcription Factors Orchestrates Reprogramming

Kathrin Plath
2017-04-13

Strategic and practical guidelines for successful structured illumination microscopy

Justin Demmerle, Cassandravictoria Innocent, Graeme Ball, Ezequiel Miron, Ian M. Dobbie, Yolanda Markaki, Lothar Schermelleh
2016-01-26

Matrin3: connecting gene expression with the nuclear matrix

Jan Attig, Jernej Ule, Christopher W J Smith
2016-12-01

PTBP1 and PTBP2 Serve Both Specific and Redundant Functions in Neuronal Pre-mRNA Splicing
2016-04-01

Rbfox Proteins Regulate Splicing as Part of a Large Multiprotein Complex LASR

Ji-Ann Lee
2016-03-28

Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)

Eric Van Nostrand, Balaji Sundararaman, Steven M Blue, Mitchell Guttman
2015-04-27

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.

Kathrin Plath, Eric Lander, Mitchell Guttman
2015-06-18

Chromosomes. A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation

Bernhard Payer, John E Froberg, David Colognori, Jeannie T. Lee
2015-04-02

Systematic discovery of Xist RNA binding proteins

Ryan Flynn, Edith Heard, Terry Magnuson
2015-07-16

A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing

Tatyana Nesterova, Andrea Cerase, Heather Coker, Lothar Schermelleh, Neil Brockdorff, Greta Pintacuda, Benoit Moindrot, Osamu Masui, Anne Grijzenhout
2015-01-19

Nuclear matrix protein Matrin3 regulates alternative splicing and forms overlapping regulatory networks with PTB

Eduardo Eyras, Jernej Ule, Jan Attig, Nicolas Bellora, Julian König, Christopher W J Smith
2015-08-05

Xist Exon 7 Contributes to the Stable Localization of Xist RNA on the Inactive X-Chromosome

Minghui Yue
2015-09-22

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins
2014-01-30

De novo prediction of PTBP1 binding and splicing targets reveals unexpected features of its RNA recognition and function

Yu Zhou
2014-12-01

X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency

Kathrin Plath, Vincent Pasque, Jason Tchieu, Rahul Karnik, Ritchie Ho, Takashi Sado
2013-07-04

The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome

Kathrin Plath, Eric Lander, Mitchell Guttman, Alon Goren, Klara Sirokman, Jesse Engreitz
2013-09-29

Promiscuous RNA binding by Polycomb repressive complex 2.

Thomas R. Cech, Chen Davidovich
2013-11-10

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

Joe W Gray
2013-05-16

TANGO: a generic tool for high-throughput 3D image analysis for studying nuclear organization

Christophe Escudé, Thomas Boudier
2012-06-02

Neuronal regulation of pre-mRNA splicing by polypyrimidine tract binding proteins, PTBP1 and PTBP2.
2012-03-07

Phase transitions in the assembly of multivalent signalling proteins

Marc C. Llaguno
2012-01-20

Cost-effective, high-throughput DNA sequencing libraries for multiplexed target capture

David Reich, Nadin Rohland
2012-08-28

Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain

Jernej Ule, Tomaž Curk, Gireesh K Bogu, Miha Modic, Christopher Shaw, Blaž Zupan

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