Michael R. Gold

1956 -

country of citizenship: Canada

educated at: Michigan State University, John Bowne High School

Michael R. Gold (born August 30, 1956) is a Canadian immunologist and cell biologist. He has served as head of the Department of Microbiology and Immunology at the University of British Columbia since July 2009. He is known for his discovery of how B-cell receptor stimulates Tyrosine phosphorylation and work in the signaling cascade of B-cell receptor. Source: Wikipedia (en)

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Articles 48

Date

Title

Authors

2020-02-24

TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma

Christoffer Hother, Anja Mottok, Robert Kridel, Tomohiro Aoki, Michael R. Gold, Robert S Molday, Adele Telenius, Nicole Wretham, Abigail Baticados, Pedro Farinha, Daniel Lai, Allen W Zhang, Diego Villa, Andrew Mungall, Ryan D Morin, Marco Marra, Christian Steidl, Libin Abraham
2019-06-03

Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation

Madison Bolger-Munro, Daniel Coombs, Michael R. Gold, Libin Abraham, Joshua Scurll
2018-02-19

The Rap2c GTPase facilitates B cell receptor-induced reorientation of the microtubule-organizing center

Jia C Wang, Caitlin Pritchard, Michael R. Gold
2017-02-06

The Rap1-cofilin-1 pathway coordinates actin reorganization and MTOC polarization at the B cell immune synapse

Michael R. Gold
2017-09-12

Limitations of Qdot labelling compared to directly-conjugated probes for single particle tracking of B cell receptor mobility

Henry Y Lu, Brian Irwin, Michael R. Gold, Daniel Coombs, Libin Abraham, Joshua Scurll
2016-10-01

Real-time 3D stabilization of a super-resolution microscope using an electrically tunable lens

Henry Y Lu, Michael R. Gold, Libin Abraham
2016-05-19

Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor

Daniel Coombs, Michael R. Gold, Calvin D Roskelley
2016-04-01

SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling

Menno J. Oudhoff, Peter J. Brown, Colby Zaph, Michael R. Gold, Cheryl Arrowsmith, David G Rattray, Toshiro Sato
2016-11-01

What goes up must come down: A tripartite Dok-3/Grb2/SHIP1 inhibitory module limits BCR signaling.

Michael R. Gold
2015-02-03

Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor

Valentin Jaumouillé, Kate Choi, Daniel Coombs, Michael R. Gold, Libin Abraham
2015-11-03

The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling

Madison Bolger-Munro, Catherine H Regnier, Shan-Yu Fung, John J. Priatel, Michael R. Gold, Stuart E Turvey, Christopher Overall, Joshua Scurll
2015-04-17

Erratum: Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor

Valentin Jaumouillé, Kate Choi, Daniel Coombs, Michael R. Gold, Libin Abraham
2014-11-03

PI3K Signaling in B Cell and T Cell Biology

Klaus Okkenhaug, Martin Turner, Michael R. Gold
2013-08-01

B-cell receptor signaling inhibitors for treatment of autoimmune inflammatory diseases and B-cell malignancies

Michael R. Gold
2013-02-11

The invasion inhibitor sarasinoside A1 reverses mesenchymal tumor transformation in an E-cadherin-independent manner

Michael R. Gold
2013-07-11

Control of the hippo pathway by Set7-dependent methylation of Yap.

Frann Antignano, Fabio M Rossi, Bernhard Lehnertz, Menno J. Oudhoff, Colby Zaph, Michael R. Gold, Cheryl Arrowsmith, Dalia Barsyte-Lovejoy
2013-02-01

Selective pharmacological inhibition of phosphoinositide 3-kinase p110delta opposes the progression of autoimmune diabetes in non-obese diabetic (NOD) mice

Kate Choi, Michael R. Gold
2011-11-07

Cofilin-mediated F-actin severing is regulated by the Rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation

Michael R. Gold
2010-12-29

TNFR1 delivers pro-survival signals that are required for limiting TNFR2-dependent activation-induced cell death (AICD) in CD8+ T cells

Michael R. Gold
2010-05-18

Preventing the activation or cycling of the Rap1 GTPase alters adhesion and cytoskeletal dynamics and blocks metastatic melanoma cell extravasation into the lungs

Michael R. Gold
2009-08-21

Localized diacylglycerol-dependent stimulation of Ras and Rap1 during phagocytosis

Roberto J. Botelho, David Mason, Michael R. Gold
2009-10-19

The Rap GTPases regulate the migration, invasiveness and in vivo dissemination of B-cell lymphomas

Michael R. Gold
2009-06-26

B cell receptor-induced phosphorylation of Pyk2 and focal adhesion kinase involves integrins and the Rap GTPases and is required for B cell spreading

Michael R. Gold
2009-06-24

Lymphocytes in the peritoneum home to the omentum and are activated by resident dendritic cells

Michael R. Gold
2008-01-01

The rap GTPases regulate B cell morphology, immune-synapse formation, and signaling by particulate B cell receptor ligands

Michele Weber, Michael R. Gold
2006-08-01

The Rap GTPases mediate CXCL13- and sphingosine1-phosphate-induced chemotaxis, adhesion, and Pyk2 tyrosine phosphorylation in B lymphocytes

Michael R. Gold, Jens Westendorf
2003-03-01

Akt is TCL-ish: implications for B-cell lymphoma

Michael R. Gold
2003-08-06

Activation of the Rap GTPases in B lymphocytes modulates B cell antigen receptor-induced activation of Akt but has no effect on MAPK activation

Michael R. Gold
2002-04-01

The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways

Michael R. Gold, Michael Affolter
2002-08-01

The Rap GTPases regulate B cell migration toward the chemokine stromal cell-derived factor-1 (CXCL12): potential role for Rap2 in promoting B cell migration

Michael R. Gold
2002-12-01

Overview of the Alliance for Cellular Signaling

Lewis C. Cantley, Madhusudan Natarajan, Deirdre Brekken, Iain Fraser, Michael R. Gold, Melanie H. Cobb, Harold E. Varmus, Robert S Sinkovits, Alfred G. Gilman, David Botstein, Mehmet Toner, Arthur Weiss, Richard H. Scheuermann, Jack E. Dixon, Henry R. Bourne, Robert Lefkowitz, Stephen Michnick, Shaun R. Coughlin, Joan Brugge, Ronald Taussig, Dennis Mock, Paul C Sternweis, Robert C Hsueh, Sangdun Choi, Susanne M Mumby, Heping Han
2002-07-01

To make antibodies or not: signaling by the B-cell antigen receptor

Michael R. Gold

Human - wd:Q18686384

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