Olaf Wiest

country of citizenship: Germany

native language: German

languages spoken, written or signed: German

occupation: academic, university teacher, researcher, organic chemist

award received: Fellow of the American Association for the Advancement of Science

official website: chemistry.nd.edu/people/olaf-wiest

Olaf Wiest (* vor 1965 in Neuwied) ist ein deutschamerikanischer Chemiker und seit 2005 Professor für theoretische organische Chemie an der University of Notre Dame (USA). Source: Wikipedia (de)

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Articles 121

Date

Title

Authors

2022-03-01

EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma

Adam D Durbin, Virangika K Wimalasena, Neekesh Dharia, Luca Mariani, Anand G Patel, Ying Shao, Paul M Park, Olaf Wiest, Brian J. Abraham, A. Thomas Look, Jun Qi, Martha L Bulyk
2021-05-27

Inhibition of Histone Deacetylases 1, 2, and 3 Enhances Clearance of Cholesterol Accumulation in Niemann-Pick C1 Fibroblasts

Dana Cruz, Andreas Ekebergh, Paul Helquist, Olaf Wiest, Frederick R. Maxfield
2020-02-04

Molecular Analysis of Membrane Targeting by the C2 Domain of the E3 Ubiquitin Ligase Smurf1

Kristen A Johnson, Robert V. Stahelin, Olaf Wiest
2020-04-05

Transition State Force Field for the Asymmetric Redox Relay Heck Reaction

Olaf Wiest, Per-Ola Norrby
2020-12-28

Design, Synthesis, and Evaluation of a Luminescent Cholesterol Mimic

Daniel Wüstner, Olaf Wiest
2019-10-21

Microsecond Timescale Simulations at the Transition State of PmHMGR Predict Remote Allosteric Residues

Olaf Wiest, Per-Ola Norrby
2019-07-08

Chemical genomics reveals histone deacetylases are required for core regulatory transcription

Berkley Gryder, Silvia Pomella, Paul M Park, Benjamin Z Stanton, Rossella Rota, Javed Khan, Olaf Wiest
2019-04-30

2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease

Olaf Wiest
2019-12-04

Regioselective Alkylation of Pyridinium Riboses

Olaf Wiest
2018-04-13

pHP-Tethered N-Acyl Carbamate: A Photocage for Nicotinamide

Olaf Wiest
2018-07-24

Application of Q2MM to predictions in stereoselective synthesis

Per-Ola Norrby, Olaf Wiest
2018-07-30

Hydrogenation catalyst generates cyclic peptide stereocentres in sequence

Eric Hansen, Olaf Wiest, Vy Dong
2017-10-27

Protein dynamics and structural waters in bromodomains

Kai Chen, Olaf Wiest
2017-06-23

Direct Visible-Light-Excited Asymmetric Lewis Acid Catalysis of Intermolecular [2+2] Photocycloadditions.

Xiaoqiang Huang, Olaf Wiest, Eric Meggers, Klaus Harms
2017-11-21

Visible-Light-Activated Asymmetric β-C-H Functionalization of Acceptor-Substituted Ketones with 1,2-Dicarbonyl Compounds

Xiaoqiang Huang, Olaf Wiest, Eric Meggers, Klaus Harms
2017-06-06

Understanding Rate Acceleration and Stereoinduction of an Asymmetric Giese Reaction Mediated by a Chiral Rhodium Catalyst

Eric Meggers, Olaf Wiest
2016-06-13

Stereoselectivity in (Acyloxy)borane-Catalyzed Mukaiyama Aldol Reactions

Per-Ola Norrby, Olaf Wiest
2016-12-09

Palladium-Catalyzed Enantioselective Heck Alkenylation of Trisubstituted Allylic Alkenols: A Redox-Relay Strategy to Construct Vicinal Stereocenters

Olaf Wiest
2016-04-11

Prediction of Stereochemistry using Q2MM.

Eric Hansen, Per-Ola Norrby, Olaf Wiest
2016-10-31

Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma

Ralph Mazitschek, Paul G. Richardson, Kenneth C. Anderson, Olaf Wiest, Stuart Schreiber, Naoya Mimura, Hiroto Ohguchi, Teru Hideshima, Ronald M Paranal, Ruben Perez-Carrasco, Francesca Cottini, Gullu T Gorgun
2016-05-10

Anomeric Effects in Sulfamides

Per-Ola Norrby, Olaf Wiest
2016-12-22

Diastereoselective Synthesis of Highly Substituted Tetrahydrofurans by Pd-Catalyzed Tandem Oxidative Cyclization-Redox Relay Reactions Controlled by Intramolecular Hydrogen Bonding

Joshua L Brooks, Olaf Wiest
2016-10-21

Single-Flask Multicomponent Synthesis of Highly Substituted α-Pyrones via a Sequential Enolate Arylation and Alkenylation Strategy.

Olaf Wiest
2016-08-03

Mechanism and Selectivity in the Pd-Catalyzed Difunctionalization of Isoprene.

Olaf Wiest
2016-06-23

Metal-Templated Design: Enantioselective Hydrogen-Bond-Driven Catalysis Requiring Only Parts-per-Million Catalyst Loading.

Thomas Cruchter, Olaf Wiest
2015-05-29

Ni-Catalyzed Alkenylation of Ketone Enolates under Mild Conditions: Catalyst Identification and Optimization

Per-Ola Norrby, Olaf Wiest
2015-04-30

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Kesinee Chotivanich, Mehdi Ghorbal, Robert V. Stahelin, Alassane Mbengue, Chea Nguon, Arjen Dondorp, Narla Mohandas, Olaf Wiest, Michael E. Pfrender, Scott J Emrich
2015-03-20

Variable active site loop conformations accommodate the binding of macrocyclic largazole analogues to HDAC8

Brandon E Haines, Olaf Wiest
2015-03-31

Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole

Brandon E Haines, Olaf Wiest
2015-03-27

Design and synthesis of a crosslinker for studying intracellular steroid trafficking pathways

Olaf Wiest
2015-09-01

Relative reactivity of alkenyl alcohols in the palladium-catalyzed redox-relay Heck reaction

Benjamin R Buckley, Olaf Wiest
2015-05-01

The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs

Dyann Wirth, Ralph Mazitschek, Huihao Zhou, Vanessa Zuzarte-Luís, Maria Manuel Dias da Mota, Susan Lindquist, Selina Bopp, Amanda K Lukens, Olaf Wiest, Emily R. Derbyshire, Jon Clardy

Human - wd:Q2018119

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