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HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

Autor

Randall S. Johnson

2000 -

veröffentlicht in: Nature Reviews Cancer

Erscheinungsdatum: 2011-12-15

Sprache: Englisch

Hauptthema: Hypoxie, Bruder oder Schwester

Zitiert Artikel 192

Datum

Titel

Autor

2011-01-01

Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3

Inger Njølstad, Neonila Szeszenia-Dabrowska, Vladimír Bencko, Valerie Gaborieau, Dawid Georgijewitsch Saridse, Paul Brennan, Diana Zelenika, Mark Lathrop, Nathaniel Rothman, Meredith Yeager, Dimitrios Trichopoulos, Paolo Boffetta, Lenka Foretová, Vladimír Janout, Eleonóra Fabiánová, Anne Tjønneland, Bas Bueno-de-Mesquita, Elio Riboli, Jolanta Lissowska, Börje Ljungberg, Kim Overvad, Demetrius Albanes, Salvatore Panico, Vittorio Krogh, Françoise Clavel-Chapelon, Kvetoslava Koppová, Kristian Hveem, Heiner Boeing, Miren Dorronsoro, Camilla Stoltenberg, Eric J Duell, Rajiv Kumar, Carmen Navarro, Jakob Linseisen, Simone Benhamou, Olivier Cussenot, Domenico Palli, Joanna Trubicka, Mattias Johansson, Kay-Tee Khaw, Rosario Tumino, Peter Selby, Rosamonde Elizabeth Banks, Jan Lubiński, Paolo Vineis, Eva Ardanaz, Grethe S Tell, Lars Vatten, Douglas Easton, Stephen Chanock, Paul D P Pharoah, Amy Hutchinson, Kevin B. Jacobs, W. Ryan Diver, Jarmo Virtamo, Zhaoming Wang, Isabelle Romieu, Susan M Gapstur, Victoria L. Stevens, Stephanie J. Weinstein, Christine Berg, Mark P. Purdue, Lee E Moore, Lambertus Kiemeney, Anush Mukeria, Katja K H Aben, Petra Peeters, Doris Lechner, Simon Heath, Oxana Shangina, Alexandru Bucur, Ghislaine Scelo, Jegor Borissowitsch Prochortschuk, Wong-Ho Chow, Peter Rudnai, Joanne S. Colt, Kendra L. Schwartz, Patricia Harnden-Mayor, Ann W Hsing, Sita H Vermeulen, Alexander Mazur, Jewegnija Alexandrowna Bulygina, Hélène Blanché, Joseph F. Fraumeni, Konstantin Iwanowitsch Skrjabin, Michael Thun
2011-09-19

siRNA-mediated knockdown of aryl hydrocarbon receptor nuclear translocator 2 affects hypoxia-inducible factor-1 regulatory signaling and metabolism in human breast cancer cells

Hirohito Sone
2011-06-01

The SirT3 divining rod points to oxidative stress
2011-04-21

The hypoxia-associated factor switches cells from HIF-1α- to HIF-2α-dependent signaling promoting stem cell characteristics, aggressive tumor growth and invasion

Garth Powis
2011-03-29

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

Johannes Schödel, Chris Pugh, Peter J. Ratcliffe, David Robert Mole
2011-03-01

SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization

Jaewon Lee, Paula I. Moreira, Sandra M. Cardoso, Clary B Clish, Pier Paolo Pandolfi, Lydia Finley
2011-02-28

SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production
2011-02-23

Hypoxia increases sirtuin 1 expression in a hypoxia-inducible factor-dependent manner
2011-01-01

The HIF pathway and erythrocytosis
2011-04-10

Roles of the human hypoxia-inducible factor (HIF)-3α variants in the hypoxia response
2011-01-01

Correlations of hypoxia-inducible factor-1α/hypoxia-inducible factor-2α expression with angiogenesis factors expression and prognosis in non-small cell lung cancer
2010-10-22

Hypoxia-inducible factors and the response to hypoxic stress
2010-06-25

Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha
2010-02

HIF-1: upstream and downstream of cancer metabolism

Gregg L. Semenza
2010-01-01

The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha

Carlos Sebastian, Jakob D Wikstrom, Ralph Weissleder, Joaquín M Espinosa, Leif W Ellisen
2010-10-22

Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress
2010-01-06

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

Sarah O'Meara, Tatiana Mironenko, Syd Barthorpe, Gemma Buck, Sarah Edkins, Gillian L Dalgliesh, Bin Tean Teh, P. Andrew Futreal, Andrew Menzies, Jon Teague, Michael Stratton, Calli Latimer, David R. Jones, Helen Davies
2010-02-04

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

Gregg L. Semenza
2010-12-30

Hypoxia-inducible factor α subunit stabilization by NEDD8 conjugation is reactive oxygen species-dependent
2010-11-01

mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α.
2010-10-20

Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha
2010-09-19

O2 regulates stem cells through Wnt/β-catenin signalling

Randall S. Johnson, Joseph C. LaManna
2010-09-14

Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression

Michael Karin
2010-08-10

AKT-ing via microRNA.
2010-07-21

HIF-2alpha deletion promotes Kras-driven lung tumor development.

Tyler Jacks
2010-07-19

Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation
2010-07-13

Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia

Jennifer Rha, Volker H. Haase
2010-05-11

PHD2 in tumour angiogenesis
2010-04-15

The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism

DeeAnn W Visk, Daniel J. Peet, Randall S. Johnson
2010-03-01

Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis
2010-02-22

The role of HIF prolyl hydroxylases in tumour growth

Panu M Jaakkola
2010-01-01

Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth

Adam J. Krieg, Erinn B. Rankin, Amato J. Giaccia

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