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Targeting mitochondria metabolism for cancer therapy

লেখক

Samuel E Weinberg

এতে প্রকাশিত: Nature Chemical Biology

তারিখে প্রকাশিত: 2015-01

ভাষা: ইংরেজি ভাষা

মূল বিষয়: কোষবিদ্যা, মাইটোকন্ড্রিয়া

Cites articles 102

তারিখ

শিরোনাম

লেখকগণ

2014-05-19

ROS function in redox signaling and oxidative stress
2014-09-03

Serine catabolism regulates mitochondrial redox control during hypoxia

Zhandong Liu, Jiangbin Ye, Jing Fan, Justin R. Cross, Chao Lu, Lydia Finley, Craig B. Thompson, Sriram Venneti
2014-08-10

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

Costas A Lyssiotis, Matteo Marchesini, Alessandro Carugo, Sahil Seth, Florian Muller, Simona Colla, Luigi Nezi, Ronald A. DePinho, Huamin Wang, Jason Fleming, Giulio F Draetta
2014-07-24

A mitochondrial switch promotes tumor metastasis

Paolo E. Porporato, Pierre Danhier, Suveera Dhup, Olivier Feron, Pierre Sonveaux, Thibaut Vazeille, Valéry L Payen, Christophe J De Saedeleer, Bernard Gallez, Caroline Bouzin, Tamara Copetti, Jhudit Pérez-Escuredo
2014-07-07

Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells

John M Asara
2014-07-07

Detouring of cisplatin to access mitochondrial genome for overcoming resistance
2014-05-27

Mitochondria as signaling organelles
2014-05-29

Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells

Courtney R Green, Adam M. Feist
2014-05-13

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

Eric Dufour, Samuel E Weinberg, Lucas B Sullivan, Gökhan M Mutlu
2014-05-04

Quantitative flux analysis reveals folate-dependent NADPH production

Jing Fan, Jiangbin Ye, Jurre J Kamphorst, Craig B. Thompson
2014-03-16

Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides

Richard Possemato, Franziska K Lorbeer, Timothy C Wang, Walter W Chen, Clary B Clish, David M. Sabatini, Kıvanç Birsoy
2014-01-01

Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments

Peter Nygren, Rolf Larsson, Stig Linder, Leoni Kunz-Schughart, Mårten Fryknäs, Linda Rickardson, Joachim Gullbo, Maria Hägg Olofsson
2014-01-01

Antioxidants accelerate lung cancer progression in mice
2014-01-01

Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer

Roland Nilsson, বামসি মুথা
2014-01-01

Targeting SOD1 reduces experimental non–small-cell lung cancer
2014-09-01

Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria

Judy Hirst
2014-06-01

Overcoming Drug Development Bottlenecks With Repurposing: Repurposing biguanides to target energy metabolism for cancer treatment
2013-09

Glutamine and cancer: cell biology, physiology, and clinical opportunities

Ralph J DeBerardinis
2013-07-04

Serine, glycine and one-carbon units: cancer metabolism in full circle

Jason W. Locasale
2013-07-01

AMPK: a target for drugs and natural products with effects on both diabetes and cancer
2013-12-01

Modulation of oxidative stress as an anticancer strategy

Isaac Harris
2013-12-03

Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia

Jing Fan, Jurre J Kamphorst, Eileen White, Joshua D Rabinowitz
2013-11-26

Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells

José A Campos-Sandoval, Jan Albrecht, Javier Márquez Gómez, Alison Colquhoun, José M. Matés, Rui Curi, Ralph J DeBerardinis, Monika Szeliga
2013-10-21

Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma

Lewis C. Cantley
2013-09-03

Oncometabolites: linking altered metabolism with cancer
2013-08-21

Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors

Eileen White
2013-06-06

The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling

Lucas B Sullivan, Eric Dufour, Ralph J DeBerardinis
2013-05-17

Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism

Lewis C. Cantley, Sarah-maria Fendt, G J Wirth, Jared R Mayers, Gregory Stephanopoulos
2013-04-30

Metformin inhibits growth and enhances radiation response of non-small cell lung cancer (NSCLC) through ATM and AMPK.
2013-03-01

Influence of metabolism on epigenetics and disease

উইলিয়াম কেলিন জুনিয়র
2013-03-07

Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.

ডেভিড ই ফিশার, Jennifer Wargo
2013-02-14

PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress

Francisca Vazquez, Clary B Clish, Hans R. Widlund

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