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PMEL Amyloid Fibril Formation: The Bright Steps of Pigmentation

author

Guillaume van Niel

1976 -

published in: International Journal of Molecular Sciences

date of publication: 2016-08-31

language: English

main subject: physiological phenomenon, macromolecular substances, membrane proteins, neoplasm protein

Cites articles 79

Date

Title

Authors

2016-06-09

Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool

Etienne Waelkens, Cary Esselens, Guillaume van Niel, Sebastian Munck, Joost Schymkowitz, Juan S. Bonifacino, Bart De Strooper, Rita Derua
2016-03-17

Study of Exosomes Shed New Light on Physiology of Amyloidogenesis

Guillaume van Niel
2016-02-25

Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice

Derya R Shimshek, Laura H Jacobson
2016-01-01

Identification of an amyloid fibril forming segment of human Pmel17 repeat domain (RPT domain)

Nikolaos N Louros
2015-10

Apolipoprotein E Regulates Amyloid Formation within Endosomes of Pigment Cells

Guillaume van Niel, Marie-Claude Potier, Leon Schurgers, Daniel Lévy, Graça Raposo
2015-12-22

The Kringle-like Domain Facilitates Post-endoplasmic Reticulum Changes to Premelanosome Protein (PMEL) Oligomerization and Disulfide Bond Configuration and Promotes Amyloid Formation
2015-06-04

Quaternary Structure Defines a Large Class of Amyloid-β Oligomers Neutralized by Sequestration

Carrie M Wilmot, Karen Ashe
2015-03-10

ADAM protease inhibitors reduce melanogenesis by regulating PMEL17 processing in human melanocytes
2015-01-01

The APOE genotype: modification of therapeutic responses in Alzheimer's disease

William A Banks, Suzanne Craft
2014-10-14

Lysophospholipid-containing membranes modulate the fibril formation of the repeat domain of a human functional amyloid, pmel17

Jennifer C Lee
2014-06-01

The amyloid state and its association with protein misfolding diseases.

Chris Dobson, Michele Vendruscolo
2014-04-01

Amyloid fibrils: the eighth wonder of the world in protein folding and aggregation
2013-06-10

BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells

Guillaume van Niel, Graça Raposo, Bart De Strooper
2013-02-06

Critical residues in the PMEL/Pmel17 N-terminus direct the hierarchical assembly of melanosomal fibrils

Ralf Max Leonhardt
2013-02-19

PMEL: a pigment cell-specific model for functional amyloid formation

Guillaume van Niel, Graça Raposo
2011-10-18

The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis

Graça Raposo, Paul Saftig, Guillaume van Niel, Eric Rubinstein, Michael S. Marks
2011-09-01

Inactivation of Pmel alters melanosome shape but has only a subtle effect on visible pigmentation

Graça Raposo, Danièle Tenza, Finn Hallböök, Klas Kullander, Shosuke Ito, Kazumasa Wakamatsu, Kristina Narfström, Leif Andersson
2011-11-01

Segmental polymorphism in a functional amyloid

Robert Tycko, Reed Wickner
2011-09-15

Mutations in or near the transmembrane domain alter PMEL amyloid formation from functional to pathogenic

Mark A. Lemmon, Graça Raposo, Danièle Tenza, Michael S. Marks, Leif Andersson, Brenda Watt
2011-01-19

Proprotein convertases process Pmel17 during secretion

Ralf Max Leonhardt
2010-08

Membrane budding and scission by the ESCRT machinery: it's all in the neck

Phyllis I Hanson
2010-12-10

Repeat domains of melanosome matrix protein Pmel17 orthologs form amyloid fibrils at the acidic melanosomal pH.

Robert Tycko, Reed Wickner
2010-11-24

Effects of pH on aggregation kinetics of the repeat domain of a functional amyloid, Pmel17

Jennifer C Lee
2010-10-01

Biology of amyloid: structure, function, and regulation
2009-12-01

The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition

Graça Raposo, Enrico M. Surace, Francesca Giordano, Valeria Marigo
2009-10

Current challenges in understanding melanogenesis: bridging chemistry, biological control, morphology, and function

Kazumasa Wakamatsu, Shosuke Ito
2009-05

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy
2009-03-26

The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

Harald Stenmark
2009-11-02

The secreted form of a melanocyte membrane-bound glycoprotein (Pmel17/gp100) is released by ectodomain shedding
2009-12-01

N-terminal domains elicit formation of functional Pmel17 amyloid fibrils

Mark A. Lemmon, Guillaume van Niel, Graça Raposo, James Shorter, Michael S. Marks, Jeffery W. Kelly, Brenda Watt, Kelvin C Luk
2009-07-31

The repeat domain of the melanosome fibril protein Pmel17 forms the amyloid core promoting melanin synthesis

Reed Wickner
2009-05-13

Lateral organization of membrane proteins: tetraspanins spin their web.

Olivier Silvie, Eric Rubinstein, Claude Boucheix

Article - wd:Q28076932

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