Inventaire - your friends and communities are your best library

Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23

author

Paul Martin

Jonathan Massey

Arthur Pratt

Amy E Anderson

John D Isaacs

Caroline Ospelt

Anne Barton

Peter Fraser

Gisela Orozco

Darren Plant

Annie Yarwood

Julie Diboll

Nishanthi Thalayasingam

Stephen Eyre

Jane Worthington

2000 -

published in: Genome Biology

date of publication: 2016-11-01

language: English

Cites articles 102

Date

Title

Authors

2015-02-19

Genetic and epigenetic fine mapping of causal autoimmune disease variants

Markus Kleinewietfeld, Nikolaos A. Patsopoulos, Mark Joseph Daly, David A. Hafler, Philip L De Jager, Vijay Kuchroo, Bradley Bernstein
2015-04-20

limma powers differential expression analyses for RNA-sequencing and microarray studies

Matthew E Ritchie, Belinda Phipson, Gordon K Smyth
2015-11-30

Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci

Anne Barton, Jane Worthington, Paul Martin, Gisela Orozco, Peter Fraser, Kate McAllister, Annie Yarwood
2015-08-07

First-In-Human, Phase 1, Randomized, Dose-Escalation Trial with Recombinant Anti-IL-20 Monoclonal Antibody in Patients with Psoriasis

James G. Krueger
2015-06-29

The support of human genetic evidence for approved drug indications

Junwen Wang, John Whittaker, Philippe Sanseau
2015-05-07

Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions

Hülya Kayserili, Stefan Mundlos, Brigitte Gilbert-Dussardier, Katerina Kraft, Martin Franke, Malte Spielmann, Eva Klopocki, Axel Visel, Darío G. Lupiáñez, Marco Osterwalder, Peter Krawitz, Stefan Haas, Renata Laxova, Denise Horn, John Marius Opitz, Bernd Timmermann
2015-05-04

Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C.

Borbala Mifsud, Filipe Tavares-Cadete, Robert Sugar, Steven W Wingett, William Grey, Philip Ewels, Peter Fraser, Cameron S. Osborne
2015-03-11

Three-dimensional genome architecture: players and mechanisms

Ana Pombo
2015-03-09

The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements

Mayra Furlan-Magaril, Borbala Mifsud, Filipe Tavares-Cadete, Biola M. Javierre, Steven W Wingett, Andrew Dimond, Cameron S. Osborne, Peter Fraser
2015-03-09

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers

Lucas D Ward, Jeffrey C Barrett, Chris Wallace, Michal Szpak, Ellen Schofield, Aaron R Quinlan, Oliver Burren, Anshul Kundaje, Neil M Walker, Manolis Kellis, Mark Joseph Daly, John A. Todd, Flemming Pociot, Luis Castaño, Richard McIndoe, Helen E Stevens, Stephen S Rich, Mary D Fortune, Type 1 Diabetes Genetics Consortium, Josyf C Mychaleckyj, Premanand Achuthan
2015-05-01

Expression of Interferon-γ Receptor Genes in Peripheral Blood Mononuclear Cells Is Associated With Rheumatoid Arthritis and Its Radiographic Severity in African Americans

Xiangqin Cui
2015-02-19

Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci

Radhika Kandaswamy, Marc Henrion, Martin Enge, Peter Fraser, Richard Houlston, Yinyin Yuan, Olivia Fletcher
2015-02-05

Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis

Ashley Budu-Aggrey, Ulrike Hüffmeier, Harry L Hebert, Chris Wallace, Jonathan Massey, Ian Bruce, James Bluett, Gary J. Donohoe, Philip Helliwell, Anthony W Ryan, Richard B. Warren, Emiliano Giardina, Ross McManus, Matthew A. Brown, André Reis, Anne Barton, Oliver FitzGerald, Helena Marzo-Ortega, Ann W Morgan, Eleanor Korendowych, Jonathan Packham
2015-06-01

Efficacy and Safety of Anti-Interleukin-20 Monoclonal Antibody in Patients With Rheumatoid Arthritis: A Randomized Phase IIa Trial

Juan D Cañete, Ladislav Šenolt
2014-01

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

Paul Flicek, Joannella Morales, Danielle Welter, Jacqueline MacArthur, Tony Burdett, Helen Parkinson, Teri Manolio, Lucia A Hindorff
2014-12

The IL-20 subfamily of cytokines--from host defence to tissue homeostasis

Sascha Rutz, Wenjun Ouyang
2014-04-01

Trimmomatic: a flexible trimmer for Illumina sequence data

Björn Usadel, Anthony M. Bolger
2014-12-11

A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping

Eric Lander, Erez Lieberman Aiden, Suhas S.P. Rao
2014-09-01

Intersection of population variation and autoimmunity genetics in human T cell activation

Barbara E. Stranger, Aviv Regev, Nir Hacohen, Noah Zaitlen, Towfique Raj, Chun Jimmie Ye, Diane Mathis, Christophe Benoist, Natasha Asinovski, Cristin McCabe
2014-08-31

Genetic variability in the regulation of gene expression in ten regions of the human brain

Sebastian Guelfi, Adaikalavan Ramasamy, Michael E. Weale, Lachlan Coin, John Anthony Hardy, Mina Ryten, North American Brain Expression Consortium, Mark R Cookson, Andrew Singleton
2014-08-13

Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C.

Sarah L Maguire, Steven W Wingett, Olivia Fletcher, Peter Fraser, Rachael Natrajan, Alan Ashworth, Frank Dudbridge, Nichola Johnson, Nick Orr, James Campbell
2014-06-26

Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cells

Barbara E. Stranger, Soumya Raychaudhuri, Gosia Trynka, Hyun Kim, Kamil Slowikowski, Philip L De Jager
2014-06-06

Expression QTL-based analyses reveal candidate causal genes and loci across five tumor types

Barbara E. Stranger, Paul D P Pharoah, Christopher A. Haiman, Simon A Gayther, Peter Kraft
2014-05-20

Genome-wide identification of expression quantitative trait loci (eQTLs) in human heart

Michiel E. Adriaens, Elisabeth M Lodder, Perry D. Moerland, Istvan Baczko
2014-03-01

Common genetic variants modulate pathogen-sensing responses in human dendritic cells

Lucas D Ward, Barbara E. Stranger, Aviv Regev, Nir Hacohen, Kamil Slowikowski, Manolis Kellis, David A. Hafler, Alexandra-Chloé Villani, Philip L De Jager, Towfique Raj, Christophe Benoist, Selina H Imboywa, Cristin McCabe, Soumya Raychaudhuri, Thomas Eisenhaure, Portia I Chipendo
2014-03-01

Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression

Benjamin P Fairfax, Vivek Naranbhai, Peter Humburg, Julian C Knight
2014-01-12

Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment

Nigel A Roberts, Simon J McGowan, Eleni Giannoulatou, Magnus D Lynch, Richard J Gibbons, Douglas Higgs
2014-07-01

Expression of interleukin (IL)-19 and IL-24 in inflammatory bowel disease patients: a cross-sectional study

Gabriela Fonseca-Camarillo, Jesus Yamamoto-Furusho
2013-09-05

An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression

Michael Kinter, Patrick M Gaffney
2013-10

Systematic identification of trans eQTLs as putative drivers of known disease associations

Luigi Ferrucci, Fernando Rivadeneira, Claudia Schurmann, André Uitterlinden, Andres Metspalu, Tõnu Esko, Alexander Teumer, Samuli Ripatti, Juha Karjalainen, Harm-Jan Westra, Harald Grallert, Veikko Salomaa, Johannes Kettunen, Markus Perola, Albert Hofman, Bruce M. Psaty, Thomas Meitinger, Christian Herder, Georg Homuth, Matthias Nauck, Alexandra Zhernakova, Daria V. Zhernakova, Joseph E. Powell, Benjamin P Fairfax, Marjolein J Peters, Yang Li, Julian C Knight, Sina A Gharib, Lili Milani, Holger Prokisch, Lude Franke, Grant W. Montgomery, Peter M. Visscher, Uwe Völker, Tim Frayling, Krista Fischer, Peter A.C. 't Hoen, Daniel A Enquobahrie, Andrew Singleton, Hanieh Yaghootkar, Konstantin Strauch, Jan H Veldink, Thomas Lumley, Joyce B J van Meurs, Michael Roden, Dena G. Hernandez, Jennifer A. Brody, Eva Reinmaa, Seiko Makino, Ritsert C Jansen
2013-12-25

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Andres Metspalu, Tõnu Esko, Harm-Jan Westra, Soumya Raychaudhuri, Jane Worthington, Mark Lathrop, Pilar Galan, Gosia Trynka, Solbritt Rantapää-Dahlqvist, Barbara E. Stranger, Tushar Bhangale, Corinne Miceli-Richard, Luis Rodriguez-Rodriguez, Niek de Vries, Alexandra Zhernakova, Jian Yang, Philippe Dieudé, Matthew A. Brown, Lude Franke, Leonid Padyukov, Sang-Cheol Bae, Javier Martin, Anne Barton, Lars Klareskog, Peter M. Visscher, Henk-Jan Guchelaar, Peter K. Gregersen, Hisashi Yamanaka, Paul P Tak, Tom Huizinga, Elizabeth W Karlson, Xavier Mariette, Philip L De Jager, Lindsey A. Criswell, Joshua C. Denny, Michiaki Kubo, Rene E Toes, Robert M Plenge, Eli A Stahl, Marieke J H Coenen, Piet L C M van Riel, Katherine A Siminovitch, Dorothée Diogo, Katherine P Liao, Jeffrey D Greenberg, Joel M Kremer, Ward Ortmann, Towfique Raj, Chikashi Terao, Anne E Eyler, Namrata Gupta, Daniel B Mirel, Mart Afj van de Laar, S Louis Bridges, Hye-Soon Lee, Miguel Angel Gonzalez-Gay, Hyon K Choi, Yoichiro Kamatani, Larry Moreland, Yuta Kochi, Akari Suzuki, Keiko Myouzen, Tsuneyo Mimori, Fumihiko Matsuda, Atsushi Takahashi
2013-11-15

A20 in inflammation and autoimmunity

Rudi Beyaert

Article - wd:Q28109583

Welcome to Inventaire

the library of your friends and communities

learn more