Pekka Kohonen

2000 -

country of citizenship: Finland

educated at: University of Cambridge, University of Turku

occupation: assistant professor

official website: ki.se/people/pekkoh

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Articles 56

Date

Title

Authors

2021-05-20

Towards FAIR nanosafety data

Nina Jeliazkova, Margarita D. Apostolova, Amélie Châtel, Paloma Gómez-Fernández, Vedrin Jeliazkov, Keld Alstrup Jensen, Nikolay Kochev, Pekka Kohonen, José María Navas, Aurica Precupas, Isabel Rodríguez-Llopis, Elise Rundén-Pran, Penny Nymark
2020-04-08

Transcriptomics in Toxicogenomics, Part III: Data Modelling for Risk Assessment

Angela Serra, Michele Fratello, Luca Cattelani, Irene Liampa, Georgia Melagraki, Pekka Kohonen, Penny Nymark, Antonio Federico, Pia Kinaret, Natasha M Sanabria, Tomasz Puzyn, Tae Hyun Yoon, Haralambos Sarimveis, Antreas Afantitis, Dario Greco, Mary Gulumian, Jang-Sik Choi, Roland C Grafström
2020-01-08

Toward Rigorous Materials Production: New Approach Methodologies Have Extensive Potential to Improve Current Safety Assessment Practices

Penny Nymark, Susan Dekkers, Remy Franken, Dario Greco, Niels Hadrup, Vesa Hongisto, Karin S Hougaard, Keld Alstrup Jensen, Pekka Kohonen, Antti J Koivisto, Miikka Dal Maso, Mikko Poikkimäki, Isabel Rodríguez-Llopis, Jorid B Sørli, Roland Grafström, Mary Gulumian
2020-04-15

Transcriptomics in Toxicogenomics, Part I: Experimental Design, Technologies, Publicly Available Data, and Regulatory Aspects

Pia Kinaret, Angela Serra, Antonio Federico, Pekka Kohonen, Penny Nymark, Irene Liampa, Karolina Jagiello, Natasha M Sanabria, Georgia Melagraki, Luca Cattelani, Michele Fratello, Antreas Afantitis, Tae Hyun Yoon, Tomasz Puzyn, Dario Greco, Mary Gulumian, Jang-Sik Choi, Roland C Grafström, Haralambos Sarimveis
2020-05-08

Transcriptomics in Toxicogenomics, Part II: Preprocessing and Differential Expression Analysis for High Quality Data

Angela Serra, Pekka Kohonen, Irene Liampa, Natasha M Sanabria, Luca Cattelani, Pia Kinaret, Karolina Jagiello, Antreas Afantitis, Tae Hyun Yoon, Dario Greco, Mary Gulumian, Jang-Sik Choi, Roland C Grafström, Haralambos Sarimveis
2020-12-11

Can an InChI for Nano Address the Need for a Simplified Representation of Complex Nanomaterials across Experimental and Nanoinformatics Studies?

Iseult Lynch, Antreas Afantitis, Thomas E Exner, Martin Himly, Vladimir Lobaskin, Philip Doganis, Anna Rybinska-Fryca, Nathan Bossa, Angela Serra, Irene Liampa, Stacey L Harper, Kaido Tämm, Pekka Kohonen, Dario Greco, Egon Willighagen, Mary Gulumian
2018-09-07

Integrated analysis of in vitro data and the adverse outcome pathway framework for prioritization and regulatory applications: An exploratory case study using publicly available data on piperonyl butoxide and liver models

Lucian Farcal, Roland Grafström, Pekka Kohonen, Barry Hardy, Thomas E Exner
2018-01

A data fusion pipeline for generating and enriching Adverse Outcome Pathway descriptions

Penny Nymark, Linda Rieswijk, Roland Grafström, Egon Willighagen, Pekka Kohonen, Chris T. Evelo, Friederike Ehrhart, Nina Jeliazkova, Haralambos Sarimveis, Georgia Tsiliki
2018-02-26

toxFlow: A Web-Based Application for Read-Across Toxicity Prediction Using Omics and Physicochemical Data

Dimitra-Danai Varsou, Georgia Tsiliki, Penny Nymark, Pekka Kohonen, Haralambos Sarimveis, Roland Grafström
2018-01-18

Macrophage sensing of single-walled carbon nanotubes via Toll-like receptors.

Pekka Kohonen, Lorenzo Stella, Reija Autio, Fernando Torres Andón, Olesja Bondarenko, Bengt Fadeel, Anna A. Shvedova, Riitta Lahesmaa, Elena R. Kisin
2018-04-01

Toxic and Genomic Influences of Inhaled Nanomaterials as a Basis for Predicting Adverse Outcome

Penny Nymark, Pekka Kohonen, Vesa Hongisto, Roland C Grafström
2017-07-03

A transcriptomics data-driven gene space accurately predicts liver cytopathology and drug-induced liver injury

Pekka Kohonen, Roland Grafström, Egon Willighagen, Rebecca Ceder, Krister Wennerberg, Samuel Kaski, Juuso A Parkkinen
2017-09-04

RDFIO: extending Semantic MediaWiki for interoperable biomedical data management

Egon Willighagen, Ola Spjuth, Roland Grafström, Pekka Kohonen, Denny Vrandečić, Samuel Lampa
2017-10-12

Enriching Nanomaterials Omics Data: An Integration Technique to Generate Biological Descriptors

Haralambos Sarimveis, Georgia Tsiliki, Roland Grafström, Pekka Kohonen, Penny Nymark
2016-03-01

High-throughput cell-based compound screen identifies pinosylvin methyl ether and tanshinone IIA as inhibitors of castration-resistant prostate cancer

Olli-Pekka Kallioniemi, Kirsi Ketola, Pekka Kohonen, Kristiina Iljin
2015

The eNanoMapper database for nanomaterial safety information

Nina Jeliazkova, Egon Willighagen, Janna Hastings, Roland Grafström, Bengt Fadeel, Haralambos Sarimveis, Pekka Kohonen, Cristian R. Munteanu, Georgia Tsiliki, Barry Hardy, Vedrin Jeliazkov, Charalampos Chomenidis, Pantelis Sopasakis, Philip Doganis, Bart Smeets, Markus Hegi, Nikolay Kochev, David Vorgrimmler
2015-01-27

Next-Generation Sequencing Reveals Low-Dose Effects of Cationic Dendrimers in Primary Human Bronchial Epithelial Cells

Pekka Kohonen, Hanna L. Karlsson, Bengt Fadeel, Neus Feliu, Yuning Zhang
2015-10-07

Proteomics Analysis Reveals Distinct Corona Composition on Magnetic Nanoparticles with Different Surface Coatings: Implications for Interactions with Primary Human Macrophages

Pekka Kohonen, Janne Lehtiö, Bengt Fadeel, Maria Pernemalm, Kjell Hultenby
2015-10-19

Systematic Identification of MicroRNAs That Impact on Proliferation of Prostate Cancer Cells and Display Changed Expression in Tumor Tissue

Pekka Kohonen, Olli-Pekka Kallioniemi, Merja Perälä, Suvi-Katri Leivonen, Elena Martens-Uzunova, Päivi Östling, Tero Aittokallio, John-Patrick Mpindi
2014-11

The first eNanoMapper prototype: A substance database to support safe-by-design

Nina Jeliazkova, Egon Willighagen, Janna Hastings, Roland Grafström, Bengt Fadeel, Haralambos Sarimveis, Pekka Kohonen, Cristian R. Munteanu, Georgia Tsiliki, Vedrin Jeliazkov, Philip Doganis, Bart Smeets, David Vorgrimmler
2014-05-23

Cancer Biology, Toxicology and Alternative Methods Development Go Hand-in-Hand

Pekka Kohonen, Roland Grafström, Ola Spjuth, Rebecca Ceder, Barry Hardy, Vesa Hongisto, Glenn Myatt
2014-01-30

Plasminogen activator urokinase expression reveals TRAIL responsiveness and supports fractional survival of cancer cells

Pekka Kohonen, Olli-Pekka Kallioniemi, Hinrich Gronemeyer, Merja Perälä
2014-11-20

Androgen receptor-interacting protein HSPBAP1 facilitates growth of prostate cancer cells in androgen-deficient conditions

Pekka Kohonen, Olli-Pekka Kallioniemi, Päivi Östling, John-Patrick Mpindi, Tiina Vesterinen, Tuomas Mirtti, Johan Lundin, Antti Rannikko, Kristiina Iljin
2014-12-30

miR-183 in prostate cancer cells positively regulates synthesis and serum levels of prostate-specific antigen

Pekka Kohonen, Olli-Pekka Kallioniemi, Päivi Östling
2014-03-01

CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation

Pekka Kohonen, José Moreira, Marja Jäättelä
2013-01

The ToxBank Data Warehouse: Supporting the Replacement of In Vivo Repeated Dose Systemic Toxicity Testing

Nina Jeliazkova, Egon Willighagen, Roland Grafström, Pekka Kohonen, Rebecca Ceder, Barry Hardy, Vedrin Jeliazkov, Christoph Helma, Lyn Healy, Emilio Benfenati, Glenn Myatt, Glyn N. Stacey
2013-04-05

Functional profiling of precursor MicroRNAs identifies MicroRNAs essential for glioma proliferation

Pekka Kohonen, Sampsa Hautaniemi, Olli-Pekka Kallioniemi, Merja Perälä, Ping Chen, Kirsi Hellström
2013-09-09

Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis

Pekka Kohonen, Olli-Pekka Kallioniemi, Boris Zhivotovsky, Merja Perälä
2012

High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer

Pekka Kohonen, Merja Perälä, John-Patrick Mpindi, Tuomas Mirtti, Olli-Pekka Kallioniemi, Kristiina Iljin
2012-03-01

ErbB2-driven breast cancer cell invasion depends on a complex signaling network activating myeloid zinc finger-1-dependent cathepsin B expression

Pekka Kohonen, Sampsa Hautaniemi, Christian Friberg Nielsen, Erkka Valo, Mads Daugaard, Jesper Nylandsted, José Moreira, Marja Jäättelä
2012-10-26

Novel pyrimidine-2,4-diamine derivative suppresses the cell viability and spindle assembly checkpoint activity by targeting Aurora kinases.

Jeroen Pouwels, Pekka Kohonen, Marko J. Kallio
2012-06

Genotoxic and epigenetic effects of silver nanoparticles

Pekka Kohonen, Bengt Fadeel, Hanna L. Karlsson

Human - wd:Q28651204

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