Charles Auffray

1951 -

country of citizenship: France

languages spoken, written or signed: French

Charles Auffray est un chercheur français né en 1951. Il dirige l’Unité de Génomique Fonctionnelle et Biologie Systémique pour la Santé de l’Institut des sciences biologiques du CNRS. Source: Wikipedia (fr)

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Le Génome Humain

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Articles 99

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2019-01-09

A Topological Data Analysis Network Model of Asthma Based on Blood Gene Expression Profiles

Charles Auffray, Sven-Erik Dahlén, Ratko Djukanovic, Craig E. Wheelock, Kian Fan Chung, Ian M. Adcock, Jeannette Bigler, Paul Skipp, Diane Lefaudeux, Bertrand De Meulder, Aruna T Bansal, Ioannis Pandis, James P R Schofield, Fabio Strazzeri
2019-04-15

IL-17-high asthma with features of a psoriasis immunophenotype

Marek Sanak, Charles Auffray, Sven-Erik Dahlén, Massimo Caruso, Paolo Montuschi, Stephen Fowler, Ian M. Adcock
2019-02-15

Ten years of Genome Medicine

Muin J. Khoury, Charles Auffray, James R. Lupski
2018-02-26

DNA methylation in childhood asthma: an epigenome-wide meta-analysis.

Cleo C van Diemen, Dan Mason, Yang Li, Juha Kere, John Wright, Francesco Forastiere, Marc Jan Bonder, Martijn C Nawijn, Judith García-Aymerich, Jose Ramon Bilbao, Tiina Laatikainen, Catherine Laprise, Charles Auffray, Manolis Kogevinas, Göran Pershagen, Olena Gruzieva, Erik Melén, Cilla Söderhäll, Jordi Sunyer, Tari Haahtela, Bert Brunekreef, Mihai Netea, Cisca Wijmenga, Jean Bousquet, Simon Kebede Merid, Nanna Fyhrquist, Daniela Porta, Mariona Bustamante, Ulrike Gehring, Harri Alenius, Gerard H. Koppelman, Maties Torrent, Leda Chatzi, Isabella Annesi-Maesano, Sabrina Llop, Marjan Kerkhof, Soesma A Jankipersadsing, Miriam F Moffatt, Stephane Ballereau, Maria Pia Fantini, Karin C Lødrup Carlsen, Vegard Hovland, Kai-Håkon Carlsen, Petter Mowinckel, Stefano Guerra, Nour Baiz, Bianca van Rijkom, Johann Pellet, Carmen Iñiguez, Nathanaël Lemonnier, Johan C de Jongste, Henriette Smit
2018-04-23

Community-driven roadmap for integrated disease maps.

Inna Kuperstein, Jan Hasenauer, Thomas Ligon, Anna Niarakis, Daniel Weindl, Rudi Balling, Alexander Mazein, Ronan Mt Fleming, Emmanuel Barillot, Reinhard Schneider, Marek Ostaszewski, Nicolas Le Novère, Charles Auffray, Andrei Zinovyev
2018-06-02

Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms.

Alexander Mazein, Andrei Zinovyev, Inna Kuperstein, Maria Manuela Nogueira, Irina Balaur, Feng He, Marek Ostaszewski, Rudi Balling, Charles Auffray, Nicolas Le Novère, Andrew Parton, Nathanaël Lemonnier, Pierre Hainaut, Emmanuel Barillot
2018-05-29

A computational framework for complex disease stratification from multiple large-scale datasets.

Jonathan van Eyll, Charles Auffray, Anthony Rowe, Ratko Djukanovic, Irina Balaur
2018-10-05

Human-like layout algorithms for signalling hypergraphs: outlining requirements

Charles Auffray, Alexander Mazein, Irina Balaur
2018-07-30

AsthmaMap: An expert-driven computational representation of disease mechanisms

Alexander Mazein, Charles Auffray
2018-05-08

Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome

Yang Xian, Massimo Caruso, Florian Singer, Marek Sanak, Charles Auffray, Sven-Erik Dahlén, Simone Hashimoto, Louise Fleming, Dominick Shaw, Paolo Montuschi, Stephen Fowler, Ian M. Adcock, Kian Fan Chung, Aruna T Bansal, Julie Corfield, Norbert Krug, René Lutter, Per S Bakke, Ioannis Pandis, Ratko Djukanovic, Doroteya Staykova, Caterina Folisi, Thomas Sandström, James P R Schofield, Anthony Rowe, Paul Skipp
2017-09

Volatile Organic Compounds Breathprinting of U-BIOPRED Severe Asthma smokers/ex-smokers cohort

Marek Sanak, Charles Auffray, Sven-Erik Dahlén, Massimo Caruso, Florian Singer
2017-02-15

A Transcriptome-driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U-BIOPRED

Matthew J Loza, Dominick Shaw, Stephen Fowler, Charles Auffray, Sven-Erik Dahlén, Kian Fan Chung, Ian M. Adcock, Stelios Pavlidis, Fred Baribaud, Julie Corfield, Bertrand De Meulder, Uruj Hoda, Christos Rossios, Barbro Dahlén, Norbert Krug, Diane Lefaudeux, Ioannis Pandis, Ratko Djukanovic, Anthony Rowe
2017-02-01

Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes

Ferran Ballester, Jordi Sunyer, Manolis Kogevinas, Emmanuelle Rial-Sebbag, Anne Cambon-Thomsen, Mirela Curin, Natalia Ballardini, Jonathan Coquet, Mariona Pinart, Raphaelle Varraso, Christian Lupinek, Benedicte Jacquemin, Jordi Mestres, Rachel Nadif, Mika J. Mäkelä, John Wright, Fanny Rancière, Francesco Forastiere, Joachim Heinrich, Carsten Bindslev-Jensen, Torsten Zuberbier, Judith García-Aymerich, Claus Bachert, Martijn C Nawijn, Charles Auffray, Rudolf Valenta, Magnus Wickman, Niklas Andersson, Erik Melén, Inger Kull, Dirkje Postma, Tari Haahtela, Bert Brunekreef, Cezmi Akdis, Marek L. Kowalski, Mubeccel Akdis, Jean Bousquet, Leena von Hertzen, Gerard H. Koppelman, Isabelle Momas, Bart Lambrecht, Marie Standl, Stefano Guerra, Cynthia Hohmann, Emilie Burte, Leda Chatzi, Pascal Demoly, Jocelyne Just, Susanne Lau, Isabelle Pin, Ulrike Gehring, Karin C Lødrup Carlsen, Anna Asarnoj, Marit Westman, Stephane Ballereau, Anna Bedbrook, Andrea von Berg, Esben Eller, Maria Pia Fantini, Theresa Keller, Kinga-Renata Kiss, Sibylle Koletzko, Irina Lehmann, Yvan Saeys, Valérie SIROUX, Christina Tischer, Daniela Porta, Xavier Basagaña, Henriette Smit
2017-06-09

Computational analysis of multimorbidity between asthma, eczema and rhinitis

Mariona Pinart, Judith García-Aymerich, Charles Auffray, Manolis Kogevinas, Rudolf Valenta, Magnus Wickman, Erik Melén, Jordi Sunyer, Dirkje Postma, Mubeccel Akdis, Jean Bousquet, Gerard H. Koppelman, Martijn C Nawijn, Yvan Saeys, Stephane Ballereau, Stefano Guerra, Nathanaël Lemonnier, Bart Lambrecht
2017-07-26

Pathway discovery using transcriptomic profiles in adult-onset severe asthma

Ratko Djukanovic, Charles Auffray, Klaus Bønnelykke, René Lutter
2017-06-16

Exposure to Traffic-Related Air Pollution and Serum Inflammatory Cytokines in Children

Bruna Gigante, Juha Kere, Nathanaël Lemonnier, Charles Auffray, Göran Pershagen, Olena Gruzieva, Erik Melén
2017-02-08

T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED.

Yike Guo, Anthony Rowe, Matthew J Loza, Ratko Djukanovic, Charles Auffray, René Lutter
2017-05-01

Genome-Wide Interaction Analysis of Air Pollution Exposure and Childhood Asthma with Functional Follow-up

Olena Gruzieva, Yohan Bossé, Elaine Fuertes, Michael Kobor, Michael Brauer, Michal Korek, Despo Ierodiakonou, Meaghan J Jones, Joachim Heinrich, Nathanaël Lemonnier, Charles Auffray, Göran Pershagen, Erik Melén, Cilla Söderhäll, Dirkje Postma, Bert Brunekreef, David C. Nickle, Jean Bousquet, Gerard H. Koppelman, Elaina A. MacIntyre, Christopher Carlsten, Carla M T Tiesler, Moira Chan-Yeung, Anita L Kozyrskyj, Marie Standl, Allan B Becker, Tom Bellander, Stephane Ballereau, W James Gauderman, Johann Pellet, Judith M Vonk
2017-12-01

Host Transcription Profile In Nasal Epithelium And Whole Blood of Hospitalised Children under two years of age with Respiratory Syncytial Virus Infection

Jeremy Farrar, Martin L. Hibberd, H Rogier van Doorn, Charles Auffray, Juliet Bryant, Bach Hue Nguyen, Thi Thu Loan Tran, Huong Ngoc Quynh Tran, Nguyen Anh Tran Dac, Hong Nhien Trinh, Nguyen Thi Thanh Hai, Bao Tinh Le Binh, Quang Tung Thai, Ngoc Quang Minh Ngo, Thi Kim Huyen Dang, Ngoc Huong Cao
2016-10-06

Severe asthma exists despite suppressed tissue inflammation: findings of the U-BIOPRED study.

Ratko Djukanovic, Matthew J Loza, Dominick Shaw, Charles Auffray
2016

Representing and querying disease networks using graph databases

Alexander Mazein, Artem Lysenko, Christopher Rawlings, Charles Auffray
2016-12-05

STON: exploring biological pathways using the SBGN standard and graph databases

Alexander Mazein, Vasundra Touré, Charles Auffray, Dagmar Waltemath, Irina Balaur, Ron Henkel
2016-11-07

Erratum to: Making sense of big data in health research: towards an EU action plan

Niklas Blomberg, Thomas Lengauer, Sophie Helen Janacek, Jeanine Houwing-Duistermaat, Ángel Honrado, Tim Hubbard, Dörthe Nickel, Vera Grimm, Inês Barroso, Ana Conesa, Marinus Eijkemans, Juan Antonio Vizcaíno, Pablo Villoslada, Peter Devilee, Norbert Graf, Xavier Serra-Picamal, Ralf-Dieter Hilgers, Rudi Balling, Jerry Lanfear, Enrique Bernal-Delgado, Magnus Rattray, Henk-Jan Guchelaar, Charles Auffray, Gianluigi Zanetti, Thierry Sengstag
2016-06-23

Making sense of big data in health research: Towards an EU action plan

Tim Hubbard, Juan Antonio Vizcaíno, Christoph Bock, Paul Flicek, Inês Barroso, Niklas Blomberg, Peter Devilee, Thomas Lengauer, Sophie H Janacek, Ana Conesa, Werner Müller, Norbert Graf, Thierry Sengstag, Ralf-Dieter Hilgers, Magnus Rattray, Enrique Bernal-Delgado, Rudi Balling, Jeanine Houwing-Duistermaat, Jerry Lanfear, Henk-Jan Guchelaar, Charles Auffray, Gianluigi Zanetti, Marinus Eijkemans
2016-08-18

The P4 Health Spectrum - A Predictive, Preventive, Personalized and Participatory Continuum for Promoting Healthspan

Leroy Hood, Ross Arena, Rudi Balling, Charles Auffray, Ze-Guang Han, Elissa Epel, Carl Lavie, Bruce McEwen, Michael Sagner, Pekka Puska, Amy McNeil
2016-12-19

Recon2Neo4j: applying graph database technologies for managing comprehensive genome-scale networks

Artem Lysenko, Christopher Rawlings, Charles Auffray, Irina Balaur
2016-03-30

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis

Juha Kere, Abbas Dehghan, Brenda Eskenazi, Asa Bradman, Marie-France Hivert, Christine Ladd-Acosta, Leanne K Küpers, Sarah E Reese, Soesma A Jankipersadsing, Gemma C Sharp, Ashish Kumar, Olena Gruzieva, Johanna Lepeule, Karen Huen, Lucas A. Salas, Hector Hernandez-Vargas, Zongli Xu, Mariona Pinart, Allan C Just, Michael C Wu, Mariona Bustamante, Jack A. Taylor, Martine Vrijheid, Inger Kull, Andrew P. Feinberg, Barbara Heude, Caroline L. Relton, Tom R. Gaunt, Stephanie J. London, Allen Wilcox, John W. Holloway, Oscar H Franco, George Davey Smith, Ahmad Vaez, Rebecca C Richmond, Nathanaël Lemonnier, Wilfried Karmaus, Wenche Nystad, Siri Eldevik Håberg, Charles Auffray, Göran Pershagen, Magnus Wickman, Liesbeth Duijts, Erik Melén, Cilla Söderhäll, Albert Hofman, Jordi Sunyer, Dirkje Postma, Wendy L McArdle, Bert Brunekreef, Augusto A Litonjua, Matthew W Gillman, Vincent W Jaddoe, Lisa F Barcellos, Harold Snieder, Janine F Felix, Joyce B J van Meurs, Paul Yousefi, Marjolein J Peters, Bonnie Joubert, Symen Ligthart, Roy Miodini Nilsen, Kelly M Bakulski, Ulrike Gehring, Gerard H. Koppelman, Simon Kebede Merid, Daniele Fallin, Carrie V Breton, Cathrine Hoyo, Andrea Baccarelli, Zdenko Herceg, Susan Ewart, Akram Ghantous, Dawn L DeMeo, Marjan Kerkhof, Isabella Annesi-Maesano, Sara E Benjamin-Neelon, Stefano Guerra, Nour Baiz, Marie Aline Charles, Monica Cheng Munthe-Kaas, Bilal M Quraishi, Celeste Eng, Fahimeh Falahi, Henning Tiemeier, Esteban Burchard
2016-07-22

Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO2 Air Pollution Exposure

Juha Kere, Stephanie J. London, Soesma A Jankipersadsing, Johanna Lepeule, Rémy Slama, Mariona Bustamante, Wenche Nystad, Charles Auffray, Göran Pershagen, Olena Gruzieva, Liesbeth Duijts, Erik Melén, Cilla Söderhäll, Jordi Sunyer, Dirkje Postma, Herman den Dekker, Jean Bousquet, Mònica Guxens, Ulrike Gehring, Isabella Annesi-Maesano, Janine F Felix, Gerard H. Koppelman, Carrie V Breton, Vincent W Jaddoe, Stephane Ballereau, Nathanaël Lemonnier, Marie Aline Charles, Tom Bellander, Christian Magnus Page, Yvonne de Kluizenaar, Simon Kebede Merid
2016-01-01

Systems Medicine: The Future of Medical Genomics, Healthcare, and Wellness

Alexander Mazein, Charles Auffray
2016-10-20

U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics

Anthony Rowe, Matthew J Loza, Massimo Caruso, Florian Singer, Stephen Fowler, Ratko Djukanovic, Marek Sanak, Charles Auffray, Alan Knox, Sven-Erik Dahlén, Louise Fleming, Paolo Montuschi, Pascal Chanez, G Roberts, Ian M. Adcock, René Lutter, Kian Fan Chung, U-BIOPRED Study Group, Diane Lefaudeux, Bertrand De Meulder, Aruna T Bansal, Julie Corfield, Ioannis Pandis, Per S Bakke, Norbert Krug, Thomas Sandström
2016-03-01

Longitudinally Stable, Clinically Defined Clusters of Patients with Asthma Independently Identified in the ADEPT and U-BIOPRED Asthma Studies

Ratko Djukanovic, Charles Auffray, Elliot S. Barnathan
2016-01-29

From genomic medicine to precision medicine: highlights of 2015.

Timothy Caulfield, Muin J. Khoury, Charles Auffray, James R. Lupski

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Charles Auffray

Series

Works 1

Le Génome Humain

Articles 99

Welcome to Inventaire