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Human neural stem cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model

published in: PLOS One

date of publication: 2007-01-17

language: English

main subject: angiogenesis, neural stem cells

Cites articles 49

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Lewis C. Cantley
2006-04-01

Brain transplantation of human neural stem cells transduced with tyrosine hydroxylase and GTP cyclohydrolase 1 provides functional improvement in animal models of Parkinson disease
2005-02-03

Priorities for clinical research in intracerebral hemorrhage: report from a National Institute of Neurological Disorders and Stroke workshop
2005-07-01

Intravenous administration of human neural stem cells induces functional recovery in Huntington's disease rat model.

Manho Kim, Kon Chu, Soon-Tae Lee, Lami Kang
2005-09-01

VEGF protects brain against focal ischemia without increasing blood--brain permeability when administered intracerebroventricularly

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2004-12-01

Distribution and in situ proliferation patterns of intravenously injected immortalized human neural stem-like cells in rats with focal cerebral ischemia

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2004-09-01

Human neural stem cells genetically modified for brain repair in neurological disorders
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Targets for vascular protection after acute ischemic stroke
2004-07-01

Stem cell therapy for human neurodegenerative disorders-how to make it work
2004-06-01

Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease
2004-06-01

New roles for VEGF in nervous tissue--beyond blood vessels
2004-01-01

Hypoxic preconditioning protects against ischemic brain injury
2004-07-27

Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex

Stephen Kelly
2004-08-01

Human neural stem cells improve sensorimotor deficits in the adult rat brain with experimental focal ischemia.

Manho Kim, Keun-Hwa Jung, Kon Chu, Soon-Tae Lee, Dong-Kyu Park, Jae-Kyu Roh, Kwon-Hee Park, Lami Kang, Sang-Wuk Jeong
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Human neural stem/progenitor cells, expanded in long-term neurosphere culture, promote functional recovery after focal ischemia in Mongolian gerbils

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2004-10-27

VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena
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Kunlin Jin
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Neurotrophins and their receptors: a convergence point for many signalling pathways
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Brain transplantation of genetically engineered human neural stem cells globally corrects brain lesions in the mucopolysaccharidosis type VII mouse
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Human neural stem cell transplantation promotes functional recovery in rats with experimental intracerebral hemorrhage.

Manho Kim, Keun-Hwa Jung, Kon Chu, Jae-Kyu Roh, Sang-Wuk Jeong
2003-06-01

Human neural stem cells can migrate, differentiate, and integrate after intravenous transplantation in adult rats with transient forebrain ischemia.

Manho Kim, Kon Chu, Sang-Wuk Jeong
2003-05-01

Adenosine triphosphate induces proliferation of human neural stem cells: Role of calcium and p70 ribosomal protein S6 kinase
2003-01-01

Effects of intraventricular infusion of vascular endothelial growth factor on cerebral blood flow, edema, and infarct volume.

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2002-01-01

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Human neural stem cells: electrophysiological properties of voltage-gated ion channels
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Vascular endothelial growth factor and angiopoietins in focal cerebral ischemia
2002-10-01

Vascular endothelial growth factor protects cultured rat hippocampal neurons against hypoxic injury via an antiexcitotoxic, caspase-independent mechanism

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What are the actual incidence and mortality rates of intracerebral hemorrhage?
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Focal cerebral ischemia causes two temporal waves of Akt activation
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Article - wd:Q33269334

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