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Stem cells in the adult mammalian central nervous system

Published in: Current Opinion in Neurobiology

Date of publication: February 1, 1999

Language: English

Main subject: nervous system

Bibliographic databases:

Cites articles 57

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Mitotic neuroblasts in the 9-day-old and 11-month-old rodent hippocampus
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In vitro analysis of the origin and maintenance of O-2Aadult progenitor cells
March 27, 1992

Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
August 1, 1992

Cooperation between PDGF and FGF converts slowly dividing O-2Aadult progenitor cells to rapidly dividing cells with characteristics of O-2Aperinatal progenitor cells
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Multipotent neural cell lines can engraft and participate in development of mouse cerebellum
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Long-distance neuronal migration in the adult mammalian brain
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Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation of subependymal cells
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Seasonal recruitment of hippocampal neurons in adult free-ranging black-capped chickadees
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FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain
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Basic fibroblast growth factor supports the proliferation of epidermal growth factor-generated neuronal precursor cells of the adult mouse CNS

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GABA and glutamate depolarize cortical progenitor cells and inhibit DNA synthesis
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Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis
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Oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells derived from adult rat spinal cord: in vitro characteristics and response to PDGF, bFGF and NT-3
February 1, 1996

Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor
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Single factors direct the differentiation of stem cells from the fetal and adult central nervous system
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In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain
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Regulation of neuronal birth, migration and death in the rat dentate gyrus
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Network of tangential pathways for neuronal migration in adult mammalian brain
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Chain migration of neuronal precursors

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Regulatory mechanisms in stem cell biology
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The adult rat hippocampus contains primordial neural stem cells
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FGF-2 is sufficient to isolate progenitors found in the adult mammalian spinal cord
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A PDGF-regulated immediate early gene response initiates neuronal differentiation in ventricular zone progenitor cells

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