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Driving CAR T-cells forward

author

Sarwish Rafiq

2000 -

published in: Nature Reviews Clinical Oncology

date of publication: 2016-03-22

language: English

Cites articles 104

Date

Title

Authors

2016-02-01

Importance of immunopharmacogenomics in cancer treatment: Patient selection and monitoring for immune checkpoint antibodies
2015-10-29

Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy

Robyn T Sussman, Marco Ruella, Nicole M Martinez, Andrei Thomas-Tikhonenko, Yoseph Barash, Stephan A Grupp, Simon F Lacey, Elad Jacoby
2015-09-15

Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo

Michael Hudecek
2015-09-10

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

Stacey Gabriel, Antje Sucker, Dirk Schadendorf, Levi A Garraway, Christian U Blank, Reinhard Dummer
2015-09-01

Chimeric Antigen Receptor T Cells against CD19 for Multiple Myeloma

Alfred L Garfall, Marcela V. Maus, Yolanda Mahnke, Adam D Cohen, Carl H. June, Bruce L. Levine, Simon F Lacey, Edward A. Stadtmauer, Dan T Vogl, Brendan M Weiss, Naseem D S Kerr, Jan Melenhorst, Karen Dengel, Adam Bagg
2015-09-01

Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia

Carl H. June, David L. Porter, Bruce L. Levine, Stephan A Grupp, Simon F Lacey, Noelle V. Frey, Alison Wakoff Loren, Adam Bagg, Sue Anne Chew, Jan Melenhorst
2015-06-09

Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma

Christine E Brown
2015-06-01

Sleeping Beauty Transposition of Chimeric Antigen Receptors Targeting Receptor Tyrosine Kinase-Like Orphan Receptor-1 (ROR1) into Diverse Memory T-Cell Populations

William G Wierda, M Helen Huls, Richard E Champlin
2015-06-25

Pembrolizumab versus Ipilimumab in Advanced Melanoma

Caroline Robert, Adil Daud, Christian U Blank
2015-03-28

A phase I clinical trial of adoptive T cell therapy using IL-12 secreting MUC-16(ecto) directed chimeric antigen receptors for recurrent ovarian cancer

Roisin E. O'Cearbhaill
2015-04-07

Phase I Hepatic Immunotherapy for Metastases Study of Intra-Arterial Chimeric Antigen Receptor-Modified T-cell Therapy for CEA+ Liver Metastases
2015-03-23

Human Epidermal Growth Factor Receptor 2 (HER2) -Specific Chimeric Antigen Receptor-Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma

Cliona M Rooney, Malcolm K Brenner, Helen Heslop, Adrian P Gee, Enli Liu, Zhuyong Mei, Bambi J Grilley, Gianpietro Dotti, Jack Meng-Fen Su, Stephen Gottschalk, Olga Dakhova, Claudia Gerken, Meenakshi Hegde, Winfried S Wels, Vita S Brawley, Alexia Ghazi, Aidin Ashoori
2015-03-04

NKG2D Ligands in Tumor Immunity: Two Sides of a Coin
2015-04-03

Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

Jonathan J Havel, Phillip Wong, Martin L Miller, Roberta Zappasodi, Ton Schumacher, Jedd D Wolchok, Chris Sander
2015-02-01

Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma

Shannon E McGettigan, Alexandria P. Cogdill, Hideho Okada, Carl H. June, Avery D. Posey
2015-02-18

Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma

Joal D Beane, Nicholas P. Restifo, Steven Rosenberg, Sid P Kerkar, Zhili Zheng, Udai S Kammula, Marybeth S Hughes, Azam V Nahvi, Steven R. Feldman, Sadik H Kassim, Mary Ann Toomey
2015-01-20

Disialoganglioside GD2 as a therapeutic target for human diseases
2015-01-06

Different cytokine and stimulation conditions influence the expansion and immune phenotype of third-generation chimeric antigen receptor T cells specific for tumor antigen GD2

Tessa Gargett, Michael P. Brown
2014-10-16

Effective response and delayed toxicities of refractory advanced diffuse large B-cell lymphoma treated by CD20-directed chimeric antigen receptor-modified T cells
2014-10-13

T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial

Steven Rosenberg
2014-10-16

Chimeric antigen receptor T cells for sustained remissions in leukemia

Yolanda Mahnke, David T Teachey, Carl H. June, David L. Porter, Bruce L. Levine, Stephan A Grupp, Simon F Lacey, Noelle V. Frey, Shannon L Maude, Richard Aplenc, Nancy J Bunin, Sue Anne Chew, Vanessa Gonzalez-Covarrubias, Jan Melenhorst, Susan R Rheingold
2014-09-01

Treatment of CD33-directed chimeric antigen receptor-modified T cells in one patient with relapsed and refractory acute myeloid leukemia
2014-08-25

Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor

Steven Rosenberg
2014-03-01

NKG2D CARs as cell therapy for cancer
2014-02-01

Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce anti-tumor activity in solid malignancies

Gregory L Beatty, Carl H. June, Bruce L. Levine
2014-02-19

Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia

Yvette Bernal, Peter G Maslak, Sergio Giralt, Malgorzata Olszewska, Monika Sugalska
2014-02-01

Diverse solid tumors expressing a restricted epitope of L1-CAM can be targeted by chimeric antigen receptor redirected T lymphocytes

Christine E Brown
2014-01-01

Design and development of therapies using chimeric antigen receptor-expressing T cells

Malcolm K Brenner, Barbara Savoldo, Gianpietro Dotti, Stephen Gottschalk
2013-09-12

T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia

Christine E Brown
2013-08-12

Treatment of malignant pleural mesothelioma by fibroblast activation protein-specific re-directed T cells

Shawn M Jensen, Maries van den Broek
2013-07-19

Anti-PD-1 antibody therapy potently enhances the eradication of established tumors by gene-modified T cells

Mark J. Smyth, Michael H. Kershaw, Phillip K. Darcy, Connie P Duong, Paul A Beavis, Liza B John, Christel Devaud, Carmen S M Yong, Melvyn T Chow
2013-07-08

Persistence and efficacy of second generation CAR T cell against the LeY antigen in acute myeloid leukemia

Amit Khot, Paul Neeson, Michael H. Kershaw, Phillip K. Darcy, Andrew M Scott, Joseph A Trapani, Mark J. Smyth, Jennifer A Westwood, Dirk Hönemann, H Miles Prince, Stefan Peinert

Article - wd:Q34046505

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