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Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling

pengarang

Jesse R Raab

Jonathan Schisler

John P Didion

Terry Magnuson

Della Yee

Joshua Starmer

diterbitkan dalam: Nature Communications

tanggal publikasi: 2015-01-27

bahasa: Inggris

subyek utama: radang

Cites articles 67

Date

Judul

Pengarang

2014-09-19

Genomic analyses of gynaecologic carcinosarcomas reveal frequent mutations in chromatin remodelling genes

Samuel V Angiuoli, Siân Jones, Victor Velculescu, Luis Alberto Diaz Jr, Laura D Wood, Mark Sausen, Lisa Kann, Christine L McCord, Manish R Shukla
2014-06-04

Roles of deletion of Arid1a, a tumor suppressor, in mouse ovarian tumorigenesis

Ren-Chin Wu
2014-02-01

The IL-6 feed-forward loop: a driver of tumorigenesis
2013-12-01

Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models

Anders Ohman, Ronny Drapkin
2013-12-01

Clear cell carcinoma of ovary and uterus

Rosalind Glasspool, Iain A McNeish
2013-08-12

Epithelial ovarian cancer experimental models

Ernst Lengyel, Daniela E. Matei, Paul Haluska, Sharon Stack
2013-05-05

Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy

Courtney Hodges, Lena Ho, Cigall Kadoch
2013-04-04

New perspectives on molecular targeted therapy in ovarian clear cell carcinoma

David Tan
2013-04-02

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

Chris Sander, Bülent Arman Aksoy, Gideon Dresdner, Ethan Cerami, Ugur Dogrusoz, Anders Jacobsen, Rileen Sinha, Jianjiong Gao, Nikolaus Schultz
2013-03-06

Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche

Grigori N. Enikolopov, Chang-il Hwang
2013-01

Cancer statistics, 2013
2013-01

ARID1a-DNA interactions are required for promoter occupancy by SWI/SNF

Cam Patterson, Jonathan Schisler, Terry Magnuson
2013-10-11

Molecular pathways: SWI/SNF (BAF) complexes are frequently mutated in cancer--mechanisms and potential therapeutic insights

Charles W Roberts
2012-12-03

ARID1A mutations in cancer: another epigenetic tumor suppressor?

Charles W Roberts
2012-09

Clear cell carcinoma of the female genital tract (not everything is as clear as it seems)
2012-08-07

Combined PI3K/mTOR and MEK inhibition provides broad antitumor activity in faithful murine cancer models

Charles M. Perou, Norman Sharpless, Patrick Dillon, David B Darr, Adam D Pfefferle, Austin J Combest, Jerry E Usary, Martin C Whittle
2012-06-26

Cytokine gene expression signature in ovarian clear cell carcinoma

Michael S Anglesio
2012-05-31

Characterization of the mechanism of action of the pan class I PI3K inhibitor NVP-BKM120 across a broad range of concentrations

Julia Kleylein-Sohn
2012-05-29

Interleukin-6 signaling pathway in targeted therapy for cancer
2012-05

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

Chris Sander, Bülent Arman Aksoy, Ethan Cerami, Ugur Dogrusoz, Boris Reva, Jianjiong Gao, Anders Jacobsen, Nikolaus Schultz, Selcuk Onur Sumer, Yevgeniy Antipin
2012-03-18

A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response

Pier Paolo Pandolfi, Nabeel Bardeesy, D. Neil Hayes, Mohit Butaney, Hiromichi Ebi, Yuchuan Wang, Daniel B Costa, Norman Sharpless, Andrew L. Kung, Lewis C. Cantley, Pasi A Jänne
2012-02-01

The genome architecture of the Collaborative Cross mouse genetic reference population
2012-01-03

An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice

Kylie Gorringe, Karen E Sheppard, Theo Mantamadiotis, Carleen Cullinane, Wayne A. Phillips, Ricky W Johnstone, Grant McArthur, Ian G. Campbell, Rodney J. Hicks, Georgina L Ryland
2012-01-01

Loss of ARID1A-associated protein expression is a frequent event in clear cell and endometrioid ovarian cancers

Joellen M Schildkraut, Andrew Berchuck
2012-02-03

Loss of ARID1A/BAF250a-expression in endometriosis: a biomarker for risk of carcinogenic transformation?
2012-05-01

Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes

Niantao Deng, Choon Kiat Ong, Dachuan Huang, Sun Young Rha, Jimmy So, Steven G. Rozen, Bin Tean Teh, P. Andrew Futreal
2011-11-23

Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types

Marjanka K Schmidt, Bert Vogelstein, Siân Jones, Victor Velculescu, Darell D. Bigner, Kenneth W Kinzler, Christine A Iacobuzio-Donahue, Michael Goggins, Ralph H. Hruban, Anirban Maitra, James R Eshleman, Xiaosong Zhang, Nickolas Papadopoulos, Sanford D Markowitz, Sami N Malek
2011-02-22

IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer

Fran Balkwill, Australian Ovarian Cancer Study Group, Charlotte Lemech, Jermaine I Coward, Probir Chakravarty, Michael S Anglesio, Kylie Gorringe, Ian G. Campbell, David Bowtell, Michael J Birrer, Hagen Kulbe, Prue A Cowin, Colin House, Aikou Okamoto, David Huntsman, Anna deFazio, Steve E Kalloger, Blake Gilks
2011-12-09

Loss of ARID1A protein expression occurs as an early event in ovarian clear-cell carcinoma development and frequently coexists with PIK3CA mutations.

Hitoshi Tsuda, Masashi Takano, Osamu Matsubara
2011-02-15

Cooperation between Pik3ca and p53 mutations in mouse mammary tumor formation.
2011-05-18

Loss of BAF250a (ARID1A) is frequent in high-grade endometrial carcinomas

Anna Lee, Randy D Gascoyne, Blake Gilks
2010-10-14

ARID1A mutations in endometriosis-associated ovarian carcinomas

Gulisa Turashvili, Anne-Marie Mes-Masson, Martin Hirst, Gavin Ha, Michael S Anglesio, Gregg B Morin, David Bowtell, Leah M Prentice, David Huntsman, Steve E Kalloger, Blake Gilks, Laura Galletta, Nataliya Melnyk, Sian Fereday, Diane M Provencher, Sohrab P Shah, Janine Senz, Melissa K McConechy, Alireza Heravi-Moussavi, Christine Chow, Jason Madore

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