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Structural differences between apoE3 and apoE4 may be useful in developing therapeutic agents for Alzheimer's disease

author

Carl Frieden

published in: Proceedings of the National Academy of Sciences of the United States of America

date of publication: 2012-05-21

language: English

main subject: Alzheimer's disease

Cites articles 36

Date

Title

Authors

2011-12-12

Small molecule structure correctors abolish detrimental effects of apolipoprotein E4 in cultured neurons

John C Voss
2011-10-05

Hydrogen/deuterium exchange and electron-transfer dissociation mass spectrometry determine the interface and dynamics of apolipoprotein E oligomerization

Richard Y-C Huang, Carl Frieden
2011-09-06

Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions
2011-09-02

Mass spectrometry-based protein footprinting characterizes the structures of oligomeric apolipoprotein E2, E3, and E4.

Carl Frieden, Michael L. Gross
2011-03-18

Structure-dependent impairment of intracellular apolipoprotein E4 trafficking and its detrimental effects are rescued by small-molecule structure correctors
2011-03-01

Apolipoprotein E in Alzheimer's disease and other neurological disorders

David M. Holtzman, Joseph M Castellano
2011-02-28

Dissociation of apolipoprotein E oligomers to monomer is required for high-affinity binding to phospholipid vesicles

Carl Frieden
2011-01-25

High ability of apolipoprotein E4 to stabilize amyloid-β peptide oligomers, the pathological entities responsible for Alzheimer's disease.

Jean-Marie Ruysschaert, Erik Goormaghtigh
2011-03-16

Mapping ApoE/Aβ binding regions to guide inhibitor discovery

Peng Lei, Xun Sun
2010-12-03

Molecular basis for the differences in lipid and lipoprotein binding properties of human apolipoproteins E3 and E4.

Michael C. Phillips
2010-11-01

The association−dissociation behavior of the ApoE proteins: kinetic and equilibrium studies

Carl Frieden
2010-01-01

Structural differences between apolipoprotein E3 and E4 as measured by (19)F NMR.

Carl Frieden
2009-08-01

The role of apolipoprotein E in Alzheimer's disease

David M. Holtzman
2009-01-01

Alzheimer's disease genetics current status and future perspectives
2009-03-23

A unified scheme for initiation and conformational adaptation of human apolipoprotein E N-terminal domain upon lipoprotein binding and for receptor binding activity
2008-12-24

Insight on the molecular envelope of lipid-bound apolipoprotein E from electron paramagnetic resonance spectroscopy

Danny M. Hatters, John C Voss
2008-12-22

Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS.
2007-01

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

Deborah Blacker, Rudolph E. Tanzi
2007-08-23

A monomeric, biologically active, full-length human apolipoprotein E.
2007-02-17

Apolipoprotein E*dipalmitoylphosphatidylcholine particles are ellipsoidal in solution
2006-07-03

Apolipoprotein E structure: insights into function

Danny M. Hatters
2006-04-01

Effect of carboxyl-terminal truncation on structure and lipid interaction of human apolipoprotein E4.

Michael C. Phillips
2005-09-02

The structure of human apolipoprotein E2, E3 and E4 in solution 1. Tertiary and quaternary structure

Gérard Siest
2005-10-01

Isoform-specific interactions of human apolipoprotein E to an intermediate conformation of human Alzheimer amyloid-beta peptide.
2005-11-08

Model of biologically active apolipoprotein E bound to dipalmitoylphosphatidylcholine

Danny M. Hatters
2002-06-01

Apolipoprotein E and Alzheimer's disease: the protective effects of ApoE2 and E3.
2002-11-01

APOE genotype in cerebrovascular disease and vascular dementia.
2001-03-06

Interaction of the N-terminal domain of apolipoprotein E4 with heparin

Robert J. Linhardt
1996-10-01

Relative efficacies of amyloid beta peptide (A beta) binding proteins in A beta aggregation.
1996-08-01

Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins
1996-11-01

An ApoE-Abeta inhibition complex in Abeta fibril extension
1994-09-01

Human apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3 and E4 isoforms

Article - wd:Q36061394

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