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Proprotein convertase subtilisin/kexin type 9 deficiency reduces melanoma metastasis in liver

author

Annik Prat

Nabil Seidah

published in: Neoplasia

date of publication: 2012-12-01

Cites articles 47

Date

Title

Authors

2012-05-01

The biology and therapeutic targeting of the proprotein convertases

Annik Prat, Nabil Seidah
2012-06-01

PCSK9 regulates neuronal apoptosis by adjusting ApoER2 levels and signaling

Kai Kysenius, Urmas Arumäe, Henri J. Huttunen
2012-01-05

[Tumor necrosis factor α and melfalan-based hyperthermic isolated limb perfusion in locally advanced extremity soft tissue sarcomas and melanomas]
2011-10-25

Comparative effects of high and low-dose simvastatin on prostate epithelial cells: the role of LDL.
2011-03-21

Total cholesterol and cancer risk in a large prospective study in Korea

Rachel Huxley, Sun Ha Jee, Jonathan M Samet, Cari Kitahara
2011-09-08

Metabolic risk factors and primary liver cancer in a prospective study of 578,700 adults.

Christel Häggström, Göran Hallmans, Annekatrin Lukanova, Tone Bjørge, Anders Engeland, Steinar Tretli, Pär Stattin, Tanja Stocks, Jonas Manjer, Hanno Ulmer, Hans Concin, Randi Selmer, Gabriele Nagel, Haakan N. Joensson, Wegene Borena, Susanne Strohmaier, Björn Lindkvist, Michael Edlinger
2011-02-01

Low-density lipoprotein cholesterol and the risk of cancer: a mendelian randomization study.

Marianne Benn, Stefan Stender, Anne Tybjærg-Hansen, Børge G. Nordestgaard, Ruth Frikke-Schmidt
2011-01-27

Circulating proprotein convertase subtilisin/kexin 9 (PCSK9) regulates VLDLR protein and triglyceride accumulation in visceral adipose tissue.

Nabil Seidah, Annik Prat, Katherine Cianflone
2010-12-08

In vivo evidence that furin from hepatocytes inactivates PCSK9

Catherine Boileau, Nabil Seidah, Annik Prat
2010-10-11

Effects of the prosegment and pH on the activity of PCSK9: evidence for additional processing events

Nabil Seidah, Antonella Pasquato
2010-04-26

Statin use and risk of prostate cancer recurrence in men treated with radiation therapy

Ralph Weichselbaum
2010-07-01

Proprotein convertase subtilisin/kexin type 9 (PCSK9) affects gene expression pathways beyond cholesterol metabolism in liver cells
2009-09-08

The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model

Annik Prat, Nabil Seidah
2009-12-01

Serum cholesterol levels in relation to the incidence of cancer: the JPHC study cohorts

JPHC Study Group, Shoichiro Tsugane, Manami Inoue
2009-07-27

Dissection of the endogenous cellular pathways of PCSK9-induced low density lipoprotein receptor degradation: evidence for an intracellular route

Nabil Seidah, Annik Prat
2009-12-16

PCSK9-deficient mice exhibit impaired glucose tolerance and pancreatic islet abnormalities

Nabil Seidah, Majambu Mbikay, Annik Prat, Michel Chrétien, Janice Mayne, Francine Sirois, Thilina Dewpura
2008-09-02

Structural requirements for PCSK9-mediated degradation of the low-density lipoprotein receptor

Helen Hobbs, Jonathan C. Cohen
2008-10-01

Association between plasma cholesterol and prostate cancer in the PSA era.

Edward Giovannucci, Elizabeth A Platz
2008-11-01

Genome-wide expression analysis of cells expressing gain of function mutant D374Y-PCSK9.

Jessica M Lindvall, Morten Mattingsdal
2008-08-01

Proprotein convertase subtilisin/kexin type 9 (PCSK9): hepatocyte-specific low-density lipoprotein receptor degradation and critical role in mouse liver regeneration.

Nabil Seidah, Annik Prat, Hélène Jacques, Jean Davignon
2007-06

The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR

Annik Prat, Nabil Seidah
2007-05

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia
2007-11-01

Sequence variation in proprotein convertase subtilisin/kexin type 9 serine protease gene, low LDL cholesterol, and cancer incidence.

Eric Boerwinkle, Aaron R. Folsom
2006-01-01

Tumor stroma and regulation of cancer development
2006-03-23

Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
2005-04-12

Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9

Jay D Horton
2005-01-27

Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment

Edward A Fisher
2005-01-16

Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9.

Alexander Pertsemlidis
2004-06-03

Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia

Annik Prat, Nabil Seidah, Jean Davignon
2004-01-15

A mutation in PCSK9 causing autosomal-dominant hypercholesterolemia in a Utah pedigree

Paul N Hopkins
2003-07-01

Current uses of isolated limb perfusion in the clinic and a model system for new strategies

Alexander Eggermont
2003-06

Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

Jean Weissenbach, Corinne Cruaud, Jean-Pierre Rabès, Michel Krempf, Nabil Seidah, Mathilde Varret, Catherine Boileau, Ludovic Villéger, Marianne Abifadel, Delphine Allard, Claudine Junien, Khadija Ouguerram, Martine Devillers, Suzanne Benjannet, Louise Wickham, Danièle Erlich, Michel Farnier, Eric Bruckert

Article - wd:Q36520700

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