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Phosphorylation of eIF4E serine 209 is associated with tumour progression and reduced survival in malignant melanoma

著者

James A. Deddens

この作品が含まれる作品: British Journal of Cancer

出版日: 2016-02-04

言語: 英語

main subject: 発がんプログレッション

Cites articles 41

Date

タイトル

著者

2015-01-23

The role of eIF4E in response and acquired resistance to vemurafenib in melanoma

Arjuna Rajakumar, Ivan Topisirovic
2015-01-01

Targeting the eIF4F translation initiation complex: a critical nexus for cancer development

ネイハム・ソネンバーグ
2014-07-27

eIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies

Alexander Eggermont, Caroline Robert
2014-07-25

The intra-tumor heterogeneity of cell signaling factors in breast cancer: p4E-BP1 and peIF4E are diffusely expressed and are real potential targets

Santiago Ramon y Cajal, Javier Cortes, Vicente Peg
2014-06-09

Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3.

Nathaniel Robichaud, Luc Furic, Ola Larsson
2014-01-01

The molecular pathology of melanoma: an integrated taxonomy of melanocytic neoplasia

Boris C. Bastian
2014

Cancer statistics, 2014
2013-12-20

Adaptation to mTOR kinase inhibitors by amplification of eIF4E to maintain cap-dependent translation

Simon J Cook
2013

Targeting eukaryotic translation in mesothelioma cells with an eIF4E-specific antisense oligonucleotide

Manish R Patel
2013-08-06

Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress

Lei Jin, Helen Rizos, Xu Dong Zhang
2013-03-18

Inhibition of Mnk kinase activity by cercosporamide and suppressive effects on acute myeloid leukemia precursors

Barbara Kroczynska
2012-02-22

The translational landscape of mTOR signalling steers cancer initiation and metastasis

Jonathan Weissman
2011-08-29

PI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axis
2011-08-10

A phase 1 dose escalation, pharmacokinetic, and pharmacodynamic evaluation of eIF-4E antisense oligonucleotide LY2275796 in patients with advanced cancer

Razelle Kurzrock, Funda Meric-Bernstam, Aung Naing
2011-01-13

Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases

Nathaniel Robichaud, Luc Furic, Louis F Stancato
2010-08-02

Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development
2010-08-02

eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression

ピエール・パオロ・パンドルフィ, ネイハム・ソネンバーグ, Nathaniel Robichaud, Luc Furic, Ola Larsson, Fred Saad, Liwei Rong
2010-04-01

Translational control in cancer

Robert J Schneider
2009-04-21

eIF4E activation is commonly elevated in advanced human prostate cancers and significantly related to reduced patient survival

Louis F Stancato, James A. Deddens
2009-03-31

Phosphorylated 4E-BP1 is associated with poor survival in melanoma

Nina Bhardwaj, Gordon B. Mills
2009-01-08

Increasing burden of melanoma in the United States

Eleni Linos, グレアム・コルディッツ, Christina A Clarke
2008-02-01

Targeting the eukaryotic translation initiation factor 4E for cancer therapy
2007-11-30

Dissecting eIF4E action in tumorigenesis

Julie Teruya-Feldstein
2007-02-01

Melanoma biology and new targeted therapy

Richard Marais, Claudia Wellbrock
2007-02-01

Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues

Saleh Ibrahim
2007-09-01

Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity

Louis F Stancato
2006-08-01

Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo

Lars Zender, Carlos Cordon-Cardo
2006-07-17

Reduction of translation initiation factor 4E decreases the malignancy of ras -transformed cloned rat embryo fibroblasts
2005-04-15

The gene expression signatures of melanoma progression
2004-03-01

Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

Carlos Cordon-Cardo
2004-12-01

Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities

Ivan Topisirovic
2003-05-01

Apoptosis and melanoma chemoresistance

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