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Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models

author

Christopher J. Schofield

Guo-Li Ming

Hongjun Song

Dana Cruz

Sama F Sleiman

David W. Killilea

Irina Gazaryan

Carsten Culmsee

Richard F. Keep

Giovanni Coppola

published in: Science Translational Medicine

date of publication: 2016-03-01

language: English

main subject: oxygen sensing

Cites articles 52

Date

Title

Authors

2014-01-01

The potential of 12/15-lipoxygenase inhibitors in stroke therapy
2014-02-08

Correlation between subacute sensorimotor deficits and brain edema in two mouse models of intracerebral hemorrhage

John H. Zhang, Qingyi Ma
2014-01-01

Promises of novel multi-target neuroprotective and neurorestorative drugs for Parkinson's disease

Orly Weinreb, Moussa B. H. Youdim, Lana Kupershmidt
2013-11-19

Hemin uptake and release by neurons and glia
2013-11-12

Iron deposits in the chronically inflamed central nervous system and contributes to neurodegeneration

Torben Moos
2013-12-01

A feed-forward loop involving Trib3, Akt and FoxO mediates death of NGF-deprived neurons
2012-11-01

ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation.

Craig B. Thompson
2012-10-11

A call for transparent reporting to optimize the predictive value of preclinical research

Story C. Landis, John R. Huguenard, Robert B. Darnell, David Howells, Susan Amara, Oswald Steward, Malcolm Macleod, Robert J Ferrante, Stanley E Lazic, Shai D Silberberg, Howard E. Gendelman
2012-06-13

Intracerebral haemorrhage: mechanisms of injury and therapeutic targets

Richard F. Keep
2012-05-21

Roles of individual prolyl-4-hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice

Alastair Buchan, Peter J. Ratcliffe
2012-04-01

Iron deficiency disrupts axon maturation of the developing auditory nerve
2012-03-14

Hypoxia-inducible factor prolyl hydroxylase inhibition: robust new target or another big bust for stroke therapeutics?
2012-02-01

A critical appraisal of experimental intracerebral hemorrhage research
2012-01-13

Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: the protective role of autophagy

Aimee Landar, Victor Darley-Usmar
2012-11-28

Emerging novel functions of the oxygen-sensing prolyl hydroxylase domain enzymes

Peter Carmeliet
2012-09-08

Metal dyshomeostasis and oxidative stress in Alzheimer's disease

Ashley I. Bush
2012-08-28

Neuron-specific prolyl-4-hydroxylase domain 2 knockout reduces brain injury after transient cerebral ischemia.

Ben Wielockx, Roland Veltkamp
2011-12-06

Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms

Susan Lindquist
2011-05-27

Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1

Akhilesh Pandey, Gregg L. Semenza
2011-05

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

Akane Kawamura, Rasheduzzaman Chowdhury, Christopher J. Schofield, Eleanor A L Bagg, Oliver King, Nathan R Rose, Michael A McDonough, Peter J. Ratcliffe, Ya-Min Tian, Ian J Clifton, Rob Klose, Timothy D W Claridge, Kar Kheng Yeoh, Lars Hillringhaus, Ivanhoe K. H. Leung, Esther C Y Woon
2011-03-29

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

Johannes Schödel, Chris Pugh, Peter J. Ratcliffe, David Robert Mole
2011-03-21

Uptake, metabolism and toxicity of hemin in cultured neurons.

Stephen R. Robinson
2010-07-01

The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells

Ling Qi, Maciej T Malecki
2010-04-01

Utilization of an in vivo reporter for high throughput identification of branched small molecule regulators of hypoxic adaptation
2010-07-01

Reactivation of hepatic EPO synthesis in mice after PHD loss

William G. Kaelin
2010-01-01

PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses

Noel G Faux, Ashley I. Bush, Adam P Gunn, Henrik Zetterberg, Kaj Blennow, Colin L. Masters, Jeffrey L. Cummings, Craig W Ritchie, Martin Ingelsson, Rudolph E. Tanzi, Justin Bedo, Andrew Tsatsanis, Lars Lannfelt, Alan Rembach
2009-07-08

Selective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathways

Gregg L. Semenza
2009-01-01

Oxygen sensors at the crossroad of metabolism

Peter Carmeliet
2009-10-30

Failure of deferoxamine, an iron chelator, to improve outcome after collagenase-induced intracerebral hemorrhage in rats
2008-07-01

Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta

Simon Wilkins, Susan A. Charman, Roberto Cappai, Ashley I. Bush, Colin L. Masters, Craig W Ritchie, Rudolph E. Tanzi, Elysia Robb, Keyla Perez, Kevin J Barnham, Xin-Qiao Du, David I Finkelstein, Katrina M Laughton, Irene Volitakis, Paul A Adlard, Mikhalina Cortes
2008-05-23

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

Peter J. Ratcliffe
2008-05-05

ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo

Daniel Geschwind

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