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The bromodomain interaction module

author

Panagis Filippakopoulos

2000 -

Stefan Knapp

published in: FEBS Letters

date of publication: 2012-05-03

language: English

Cites articles 101

Date

Title

Authors

2012-03-30

Histone recognition and large-scale structural analysis of the human bromodomain family

Panagis Filippakopoulos, Sarah Picaud, Anne-Claude Gingras, Anthony Pawson, Rudolf Volkmer-Engert, Susanne Müller, Stefan Knapp, Cheryl Arrowsmith, Dalia Barsyte-Lovejoy, Ildiko Felletar, Tracy Keates
2012-03-15

Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family

Sarah Picaud, Panagis Filippakopoulos, Oleg Fedorov, Stefan Knapp, Olaf Morgenstern, Franz Bracher
2011-09-01

Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification

Saadi Khochbin, Emilie Montellier, Sophie Rousseaux, Qin Zhu
2011-02-01

Rational therapeutic combinations with histone deacetylase inhibitors for the treatment of cancer
2011-10-02

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

Gerard Drewes, Tony Kouzarides, Mark A. Dawson, Sam Robson, Carsten Hopf, Olivier Mirguet, Brian Huntly, Marcus Bantscheff, Mikhail M Savitski, Antje Dittmann, Carola Huthmacher
2011-09-13

Bromodomains as therapeutic targets

Stefan Knapp
2011-05-31

Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes

Andrew Billin, Amy E Campbell, Roland Gamsjaeger, Joel P Mackay, Ross Hardison
2011-11-14

Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes

Eric Verdin, Melanie Ott, Martina Schnölzer, Katrin Kaehlcke, Sungyoo Cho, Dwayne Bisgrove
2011-12-23

A Poised Chromatin Platform for TGF-β Access to Master Regulators

Dinshaw J. Patel, Joan Massagué Solé, Vesa Kaartinen, Lorenz Studer
2011-02-10

A unique chromatin signature uncovers early developmental enhancers in humans

Alvaro Rada-Iglesias
2011-07

Structural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3

Andrew Billin
2011-05-19

Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions

Alexander J Ruthenburg, Haitao Li, Thomas A Milne, Beatrix Ueberheide, Charles David Allis
2011-04-22

A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in Cardiomyocytes
2011-01-27

Rational design of cyclic peptide modulators of the transcriptional coactivator CBP: a new class of p53 inhibitors
2011-09-16

BET bromodomain inhibition as a therapeutic strategy to target c-Myc

Madeleine Lemieux, Efstathios Kastritis, Christopher R. Vakoc, Andrew L. Kung, Paul G. Richardson, Kenneth C. Anderson, Richard A. Young, William C Hahn, Anna C Schinzel, P Leif Bergsagel, Irene Ghobrial, Jake E Delmore, Hannah Jacob, Ronald M Paranal, Constantine S Mitsiades, Marta Chesi
2011-09-06

3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands

Panagis Filippakopoulos, Oleg Fedorov, Stuart J. Conway, Stefan Knapp, David S Hewings, Carl Philpott, Tom D Heightman, Sarah Picaud, Brian D Marsden, Sagar Uttarkar
2010-02-19

Regulation of cellular metabolism by protein lysine acetylation
2010-12-23

Selective inhibition of BET bromodomains

Panagis Filippakopoulos, Sarah Picaud, Yuchuan Wang, Oleg Fedorov, Andrew L. Kung, Stefan Knapp, Tyler T Hickman, Olaf Wiest, Ildiko Felletar, Carl Philpott, Tom D Heightman
2010-12-23

Suppression of inflammation by a synthetic histone mimic

Ivan Marazzi, Charles M. Rice, Julia H. White, Edwige Nicodeme, Kate L. Jeffrey, Rohit Chandwani
2010-03-04

Mixed lineage leukemia: histone H3 lysine 4 methyltransferases from yeast to human
2010-03-05

Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain

Takashi Umehara, Shigeyuki Yokoyama
2010-08-01

Cecr2 mutations causing exencephaly trigger misregulation of mesenchymal/ectodermal transcription factors
2010-09-20

Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark
2010-09-16

Functional characterization of ATAD2 as a new cancer/testis factor and a predictor of poor prognosis in breast and lung cancers

Saadi Khochbin, Pascal Barbry
2010-07-09

TIF1gamma controls erythroid cell fate by regulating transcription elongation

Leonard I. Zon
2010-12-16

TRIM24 links a non-canonical histone signature to breast cancer

Dinshaw J. Patel, Or Gozani, Xiaobing Shi, Dirk Schwarzer, Michelle Craig Barton, William Plunkett, Bruce J Aronow, Wolfgang Fischle, Mien-Chie Hung
2010-01-01

KAP1 controls endogenous retroviruses in embryonic stem cells

Daniel B. Constam, Johan Jakobsson, François Spitz, Tugce Aktas, Pierre V Maillard, Helen M Rowe
2010-09-10

Interaction of propionylated and butyrylated histone H3 lysine marks with Brd4 bromodomains
2010-06-10

Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression

Thomas A Milne, Haitao Li, Charles David Allis
2010-04-06

Structural insights into selective histone H3 recognition by the human Polybromo bromodomain 2

Zachary Charlop-Powers
2009-08-14

Lysine acetylation targets protein complexes and co-regulates major cellular functions

Michael Lund Nielsen, Jesper V. Olsen, Chunaram Choudhary, Florian Gnad, Matthias Mann
2009-10-01

Cooperative binding of two acetylation marks on a histone tail by a single bromodomain

Saadi Khochbin, Jeroen Krijgsveld, Karin Sadoul, Darren J Hart, Sophie Rousseaux, Christoph W Müller

Article - wd:Q38019699

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