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The sirtuins, oxidative stress and aging: an emerging link

published in: Aging

date of publication: 2013-03-01

language: English

main subject: enzyme, inorganic compound

Cites articles 56

Date

Title

Authors

2012-08-01

Caloric restriction: is mammalian life extension linked to p53?
2012-07-01

An autoregulatory loop reverts the mechanosensitive Sirt1 induction by EGR1 in skeletal muscle cells
2012-03-13

SIRT3 protein deacetylates isocitrate dehydrogenase 2 (IDH2) and regulates mitochondrial redox status
2012-02-22

The sirtuin SIRT6 regulates lifespan in male mice

Ziv Bar-Joseph
2011-11-11

Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

Johan Auwerx, Jungwoo Kim, Xiaoyang Su, Quan Hao
2011-09-01

Repairing split ends: SIRT6, mono-ADP ribosylation and DNA repair

Vera Gorbunova
2011-09-21

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

Linda Partridge, George L Sutphin, Filipe Cabreiro, Rafael P Vázquez-Manrique, Matthew D Piper, David Gems, Matt Kaeberlein, Catherine Au
2011-12

The first identification of lysine malonylation substrates and its regulatory enzyme

Junbiao Dai, David B. Lombard, Eric Verdin, Minjia Tan
2011-10-01

SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome

Johanna Kuusisto, Alena Stančáková, Markku Laakso, C. Ronald Kahn, Christopher B Newgard, Eric Verdin, Tadahiro Shimazu, Bradley Aouizerat
2011-06-01

SIRT6 promotes DNA repair under stress by activating PARP1

Xiao Tian
2011-03-01

SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization

Jaewon Lee, Paula I. Moreira, Sandra M. Cardoso, Clary B Clish, Pier Paolo Pandolfi, Lydia Finley
2011-02-01

Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress

Mitchell C Coleman, Douglas R Spitz, Haiyan Jiang
2011-02-28

SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production
2011-02-01

SIRT-ain relief from age-inducing stress
2011-02-01

Reduced mitochondrial function in obesity-associated fatty liver: SIRT3 takes on the fat.
2010

A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans

Siegfried Hekimi
2010-12-01

Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation

Matthew D. Hirschey, Eric Verdin
2010-11-24

Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction
2010-10-22

Induction of Sirt1 by mechanical stretch of skeletal muscle through the early response factor EGR1 triggers an antioxidative response
2010-09-20

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

Matthew D. Hirschey, Eric Verdin, Marcia C. Haigis, Lydia Finley
2010-06

How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)

Kim Zarse, Michael Ristow
2010-03-04

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

Carrie A. Grueter, David B. Lombard, Asish K Saha, Matthew D. Hirschey, James Bain, Neil B Ruderman, Eric Verdin, C. Ronald Kahn, Christopher B Newgard, Tadahiro Shimazu, Olga R Ilkayeva, Enxuan Jing, Robert V Farese
2010-01-01

SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress

Douglas R Spitz
2009-01-01

How mitochondria produce reactive oxygen species

Michael P. Murphy
2009-07-09

Calorie restriction alters mitochondrial protein acetylation

David B. Lombard
2008-12-11

The overexpression of major antioxidant enzymes does not extend the lifespan of mice

Holly Van Remmen, Arlan G. Richardson, Jan Vijg
2008-11-28

SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

David Sinclair
2008-11-13

Overexpression of SIRT1 protects pancreatic beta-cells against cytokine toxicity by suppressing the nuclear factor-kappaB signaling pathway
2008-05

Reconciling the chemistry and biology of reactive oxygen species

Christine Winterbourn
2008-03-12

SirT1 regulates energy metabolism and response to caloric restriction in mice

Sean Crawford, Mary-Ellen Harper
2008-01-31

Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice
2007-10

Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress

Kim Zarse, Tim J Schulz, Marc Birringer, Michael Ristow

Article - wd:Q38087848

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