Michael P. Murphy

1963 -

languages spoken, written or signed: English

educated at: University of Cambridge

occupation: biochemist

award received: Hill Tinsley Medal

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Articles 264

Date

Title

Authors

2022-03-16

MitoQ Inhibits Human Breast Cancer Cell Migration, Invasion and Clonogenicity

Luca X Zampieri, Caroline Bouzin, Davide Brusa, Carine Michiels, Bernard Gallez, Michael P. Murphy, Paolo E. Porporato, Pierre Sonveaux, Thibaut Vazeille
2022-07-15

Native chemical ligation approach to sensitively probe tissue acyl-CoA pools

Hiran A Prag, Richard C Hartley, Michael P. Murphy
2022-03-15

MitoQ Prevents Human Breast Cancer Recurrence and Lung Metastasis in Mice

Luca X Zampieri, Françoise Derouane, Caroline Bouzin, Francois P. Duhoux, Michael P. Murphy, Paolo E. Porporato, Pierre Sonveaux, Thibaut Vazeille, Valéry L Payen
2022-09-15

Rapid and selective generation of H2S within mitochondria protects against cardiac ischemia-reperfusion injury

Michael P. Murphy
2021-12-23

Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism

Christopher A. Powell, Michael P. Murphy, Christian Frezza
2021-11-13

A Multi-Omics Longitudinal Aging Dataset in Primary Human Fibroblasts with Mitochondrial Perturbations

Gabriel Sturm, Andres Cardenas, Daniel W Belsky, Michael P. Murphy
2020-04-16

Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice

Luz P Blanco, Michael P. Murphy, Mariana J. Kaplan, Ralph C Budd, Karen A Fortner, Hege L Pedersen, Andras Perl
2020-05-11

Stable mitochondrial CICIII2 supercomplex interactions in reptiles compared to homeothermic vertebrates

Amanda Bundgaard, Michael E Harbour, Michael P. Murphy, Angela Fago
2020-05-14

How should we talk about metabolism?

Michael P. Murphy, Luke A. J. O'Neill
2020-06-05

Isolating adverse effects of glucocorticoids on the embryonic cardiovascular system

Noor E W D Teulings, Youguo Niu, Katie Skeffington, Lisa M Nicholas, Emily Camm, Michael P. Murphy, Susan E Ozanne, Dino A Giussani
2020-06-15

Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis

Chenzhi Jing, Tomas Castro-Dopico, Zewen K Tuong, John R Ferdinand, Si Chong Laurence Lok, Gemma D Banham, M Zaeem Cader, Mariana J. Kaplan, Randall S. Johnson, Michael P. Murphy, Menna R Clatworthy
2020-07-01

Reply to: In vivo quantification of mitochondrial membrane potential

Orian Shirihai, Michael P. Murphy, David B Shackelford
2020-07-24

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

Stephen C Cunnane, Eugenia Trushina, Cecilie Morland, Alessandro Prigione, Zane B. Andrews, Anne Eckert, Jack H Jhamandas, Oliver Kann, William F. Martin, Paula I. Moreira, Michael P. Murphy, Klaus-Armin Nave, Frédéric Saudou, Mark Mattson, Linda H Bergersen, M. Flint Beal
2020-08-17

Active RNA interference in mitochondria

Jinzhong Lin, Michael P. Murphy, Xiang-Dong Fu, Xiaorong Zhang, Kurt Hoogewijs
2020-08-19

Translatable mitochondria-targeted protection against programmed cardiovascular dysfunction

Kimberley Botting, Katie Skeffington, Beth A. Allison, K L Brain, Nozomi Itani, Angela Logan, Andrew J. Murray, Michael P. Murphy, Dino A Giussani
2020-11-19

Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI

Kerstin N Timm, John A Henry, Michael S Dodd, Julian L Griffin, Michael P. Murphy, Damian J. Tyler
2020-12-09

Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production

Takafumi Suzuki, Richard C Hartley, Michael P. Murphy, Albena Dinkova-Kostova
2019-01-18

Malonylation of GAPDH is an inflammatory signal in macrophages

Silvia Galván-Peña, Sergio Covarrubias, Vincent P. Kelly, Michael P. Murphy, Luke A. J. O'Neill
2019-01-01

APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS

Daniele Ghezzi, Enrico Bertini, Michael P. Murphy, James A Nathan, Carlo Viscomi, Erika Fernandez-Vizarra, Massimo Zeviani
2019-01-31

Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo

Stuart T Caldwell, Sabine Arndt, John R Ferdinand, Thomas Krieg, Michael P. Murphy, Menna R Clatworthy, Lee M Booty
2019-02-26

Metabolic adaptations during extreme anoxia in the turtle heart and their implications for ischemia-reperfusion injury

Anja V Gruszczyk, Michael P. Murphy, Angela Fago
2019-01-01

Coupling Krebs cycle metabolites to signalling in immunity and cancer

Michael P. Murphy, Christian Frezza
2019-05-09

Detection of changes in mitochondrial hydrogen sulfide i n vivo in the fish model Poecilia mexicana (Poeciliidae)

Michael P. Murphy, Gigi Y Lau, Sabine Arndt
2019-11-21

Species- and tissue-specific differences in ROS metabolism during exposure to hypoxia and hyperoxia plus recovery in marine sculpins

Gigi Y Lau, Sabine Arndt, Michael P. Murphy, Jeffrey G Richards
2019-07-01

Oncogenic KRAS Induces NIX-Mediated Mitophagy to Promote Pancreatic Cancer

Timothy J Humpton, Gina M DeNicola, Melissa A Yao, Priya Alagesan, Michael P. Murphy, Gerard Evan, Karen Vousden, David Tuveson
2019-09-01

Rerouting metabolism to activate macrophages

Michael P. Murphy
2018-05-09

Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice

Martin R. Bennett, Michael P. Murphy
2018-08-22

Altered cellular redox homeostasis and redox responses under standard oxygen cell culture conditions versus physioxia

Gary Smerdon, Michael P. Murphy
2018-08-15

Ischemic preconditioning protects against cardiac ischemia reperfusion injury without affecting succinate accumulation or oxidation

Ana-Mishel Spiroski, Ana S.H. Costa, Anja V Gruszczyk, Christian Frezza, Michael P. Murphy, Thomas Krieg
2018-10-31

Mitochondrial superoxide generation induces a parkinsonian phenotype in zebrafish and huntingtin aggregation in human cells

Brígida R Pinho, Sara D Reis, Michael P. Murphy, Jorge M. A. Oliveira
2018-11-05

Mitochondria as a therapeutic target for common pathologies

Michael P. Murphy
2018-09-19

Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly

Anja V Gruszczyk, Thomas Krieg, David Carling, Michael P. Murphy

Human - wd:Q37391317

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