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Biophysical groundwork as a hinge to unravel the biology of α-synuclein aggregation and toxicity

author

Nicoletta Plotegher

Luigi Bubacco

published in: Quarterly Reviews of Biophysics

date of publication: 2014-01-21

main subject: Synuclein

Cites articles 200

Too many entities requested (216). Only 200 are displayed.

Date

Title

Authors

2013-01-25

FTIR spectroscopic imaging of protein aggregation in living cells

Lisa M Miller
2013-01-31

Triggering of inflammasome by aggregated α-synuclein, an inflammatory response in synucleinopathies

Nicoletta Plotegher, Isabella Tessari, Gaia Codolo, Marco Brucale, Luigi Bubacco
2013-04-16

A label-free, quantitative assay of amyloid fibril growth based on intrinsic fluorescence

Chris Dobson, Alexander K Buell, Clemens F Kaminski, Dorothea Pinotsi, Gabriele S Kaminski Schierle
2013-02-20

A novel α-synuclein missense mutation in Parkinson disease

Anthony H V Schapira, J M Cooper
2013

Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis
2013-02-19

Large α-synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking
2013-02-12

α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy?

Patricia Limousin, Andrew John Lees, John Anthony Hardy, Niall P Quinn, Janice Holton
2013-02-27

The dynamic structure of α-synuclein multimers

Thomas C Pochapsky
2013-07-01

β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons.

Roland Benz, Markus Zweckstetter, G. Taschenberger, J. Toloe, J. Tereshchenko, Jasper Akerboom, P. Wales, Stefan Becker, T.F. Outeiro, Loren L Looger, Mathias Bähr, Kügler S
2013-01-01

Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia

Eliezer Masliah
2013-04-22

Superresolution imaging of amyloid fibrils with binding-activated probes

Lawrence Rajendran, Alice Soragni, Helge Ewers, Jonas Ries, Adriano Aguzzi, Simone Hornemann
2013

Site-specific perturbations of alpha-synuclein fibril structure by the Parkinson's disease associated mutations A53T and E46K

Julia George, Chad M. Rienstra
2013-01-22

Aggregation and neurotoxicity of recombinant α-synuclein aggregates initiated by dimerization
2013-05-14

The many faces of alpha-synuclein mutations

Christine Klein
2012-07-13

Molecular composition of sub-stoichiometrically labeled α-synuclein oligomers determined by single-molecule photobleaching
2012-10-01

Bacterial in-cell NMR of human α-synuclein: a disordered monomer by nature?
2012-08

Protein degradation pathways in Parkinson's disease: curse or blessing

Lara Wahlster, Darius Ebrahimi-Fakhari
2012

Common features at the start of the neurodegeneration cascade

Vladimir Uversky, Albert Galera-Prat, Alejandro Valbuena, Javier Oroz, Mariano Carrión-Vázquez, Douglas V Laurents, Margarita Menéndez, Marta Bruix
2012-08-24

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Charles R Vanderburg
2012-05-01

Direct observation of the interconversion of normal and toxic forms of α-synuclein

David Klenerman, Nunilo Cremades, Andrey Y Abramov, Allen Y Chen, Angel Orte, Massimo Sandal, Richard W Clarke, Francesco Antonio Aprile, Carlos W. Bertoncini, Nicholas W. Wood, Tuomas Knowles, Chris Dobson
2012-08-03

Single-channel electrophysiology reveals a distinct and uniform pore complex formed by α-synuclein oligomers in lipid membranes

Johannes Levin, Armin Giese
2012-11

Alpha-synuclein pore forming activity upon membrane association

Nicoletta Plotegher, Laura Tosatto, Isabella Tessari, Leonardo Ricci, Mauro Dalla Serra, Luigi Bubacco
2012-06-20

Characterization of semisynthetic and naturally Nα-acetylated α-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of α-synuclein

Hilal Lashuel, Bruno Fauvet, Igor Dikiy, Mohamed-Bilal Fares
2012-06-11

N-terminal acetylation of α-synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer

Sheena Radford, Alison E. Ashcroft
2012-02-09

Mutant protein A30P α-synuclein adopts wild-type fibril structure, despite slower fibrillation kinetics

Julia George, Chad M. Rienstra
2012-11-16

Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice

John Q. Trojanowski
2012-02-07

α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer

Hilal Lashuel, Bruno Fauvet, Eliezer Masliah, Mohamed-Bilal Fares, Carole Desobry, Michel Prudent, Elpida Tsika, Darren J Moore
2012-03-01

Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo

Michael K Lee, Emanuela Colla, Poul Henning Jensen
2012-03-12

Structural intermediates during α-synuclein fibrillogenesis on phospholipid vesicles

Julia George, Chad M. Rienstra
2012-03-26

α-Synuclein knockout mice have cognitive impairments

Viktor Kokhan, Marina A Afanasyeva
2012-12-13

Covalent α-synuclein dimers: chemico-physical and aggregation properties

Dhruv Kumar, Laura Tosatto, Isabella Tessari, Marco Brucale, Luigi Bubacco, Marco Bisaglia, Daniel Aioanei, Patrizia Polverino de Laureto
2012-05-01

Prion-like spread of protein aggregates in neurodegeneration

Don W. Cleveland

Article - wd:Q38180144

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