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Muscle wasting in disease: molecular mechanisms and promising therapies

forfatter

Shenhav Cohen

James A Nathan

udgivet i: Nature Reviews Drug Discovery

dato for udgivelse: 2015-01-01

Cites articles 200

Too many entities requested (253). Only 200 are displayed.

Date

Titel

Forfattere

2014-02-24

Trim32 reduces PI3K-Akt-FoxO signaling in muscle atrophy by promoting plakoglobin-PI3K dissociation

Steven P. Gygi
2013-01-01

Cellular and molecular mechanisms of muscle atrophy
2013-05-28

Myostatin/activin pathway antagonism: molecular basis and therapeutic potential
2013-02-01

MST1, a key player, in enhancing fast skeletal muscle atrophy
2013-09-03

SIRT1 protein, by blocking the activities of transcription factors FoxO1 and FoxO3, inhibits muscle atrophy and promotes muscle growth
2013-03-01

Increased Smad signaling and reduced MRF expression in skeletal muscle from obese subjects

Andrew J. McAinch, David Cameron-Smith, John B Dixon
2013-12-02

An antibody blocking activin type II receptors induces strong skeletal muscle hypertrophy and protects from atrophy

Shinji Hatakeyama
2013-11-01

BMP signaling controls muscle mass

Roberta Sartori, Bert Blaauw, Elena Enzo, Etienne Mouisel, Luana Toniolo, Sigmar Stricker, Sirio Dupont
2013-01-29

Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1α-Fndc5 pathway in muscle
2013-07-28

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death

Daniel J. Anderson, Thomas O'Brien
2013-03-21

PPARβ/δ regulates glucocorticoid- and sepsis-induced FOXO1 activation and muscle wasting
2013-06-01

The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy

Valentina Proserpio, Raffaella Fittipaldi, James G Ryall, Vittorio Sartorelli
2013-03-13

Myostatin suppression of Akirin1 mediates glucocorticoid-induced satellite cell dysfunction

Yanjun Dong
2013-01-05

Mechanisms stimulating muscle wasting in chronic kidney disease: the roles of the ubiquitin-proteasome system and myostatin
2013-10-02

Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models

Rosanna Piccirillo, Fabio Demontis, Norbert Perrimon
2013-05-09

Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy

Francesco Loffredo, Steven M. Jay, Nikolaos Psychogios
2013-06-10

Effect of resistance exercise contraction mode and protein supplementation on members of the STARS signalling pathway

Severine Lamon
2013-04-16

Acute peripheral tissue effects of ghrelin on interstitial levels of glucose, glycerol, and lactate: a microdialysis study in healthy human subjects

Niels Møller, Jens Otto Lunde Jørgensen, Esben Thyssen Vestergaard
2012-08-01

Ubiquitylation by Trim32 causes coupled loss of desmin, Z-bands, and thin filaments in muscle atrophy

Shenhav Cohen, Steven P. Gygi
2012-12-01

A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy

Bruce Spiegelman, Nicholas P Greene, Jennifer L Estall, Brian A Irving, Jorge L Ruas, Leslie Leinwand
2012-01-30

The E3 ubiquitin ligase TRAF6 intercedes in starvation-induced skeletal muscle atrophy through multiple mechanisms

Ashok Kumar
2012-05-16

Rel A/p65 is required for cytokine-induced myotube atrophy
2012-04-16

Satellite cell senescence underlies myopathy in a mouse model of limb-girdle muscular dystrophy 2H

Elena Kudryashova
2012-08-01

The p97/VCP ATPase is critical in muscle atrophy and the accelerated degradation of muscle proteins
2012-11-01

Development of proteasome inhibitors as research tools and cancer drugs
2012-08-30

Dexamethasone-induced skeletal muscle atrophy was associated with upregulation of myostatin promoter activity
2012-12-15

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Peter J. Hotez, Louisa Degenhardt, Theo Vos, Mohsen Naghavi, Rafael Lozano, Rasmus Havmoeller, Farshad Pourmalek, Lyn March, Marlene Fransen, Fiona Blyth, Katrina Ortblad, Jacqueline Mabweijano, Bernadette Thomas, Ella Sanman, Emmanuela Gakidou, Jessica Singleton, Karen Sliwa, Emelia J. Benjamin, Catherine Michaud, Rita Krishnamurthi, Ana Olga Mocumbi, Nicholas Kassebaum, Rashmi Jasrasaria, Leslie Mallinger, Jon-Paul Khoo, Suzanne Barker-Collo, Richard Matzopoulos, Victor Aboyans, Rakesh Aggarwal, Summer Lockett Ohno, Doruk Ozgediz, Frederick P. Rivara, Bongani Mayosi, Christopher J. L. Murray, Nabila Dahodwala, Diego De Leo, Ralph L Sacco, Majid Ezzati, Valery Feigin, Ziad A Memish, Michelle L Bell, Gregory R. Wagner, Adofo Koranteng, John J. McGrath, Jeffrey A Towbin, Saad Omer, Monica Cortinovis, Abraham D Flaxman, Steven Colan, Paul S F Yip, Tony Merriman, Jonathan Carapetis, E Ray Dorsey, Mary M McDermott, James Harrison, Martin O'Donnell, Richard C. Franklin, James Dean Wilkinson, Nicole Johns, Alan D. Lopez, Esteban Porrini, Soufiane Boufous, Bruno Hoen, Mohammad A AlMazroa, Laurie S Anderson, Derrick A Bennett, Aref A Bin Abdulhak, Sumeet S Chugh, Luc E Coffeng, Leslie T Cooper, Benjamin C. Cowie, Don C Des Jarlais, Samath D Dharmaratne, Beth Ebel, Eduardo Undurraga, Anthony D. Woolf, Jerry Puthenpurakal Abraham, Peter McBurney, Lakshmi Vijayakumar, Kyle Foreman, Stephen Lim, Kenji Shibuya, Stephanie H Ahn, Larry Baddour, David M Bartels, Kavi Bhalla, Boris Bikbov, Gretchen L Birbeck, Ian Bolliger, Chiara Bucello, Samantha M Colquhoun, K Ellicott Colson, Matthew A Corriere, Karen Courville de Vaccaro, William G. Couser, Marita Cross, Kaustubh C Dabhadkar, Allyne M Delossantos, Julie Denenberg, Mohammad H Forouzanfar, Francis Gerry R Fowkes, Ralph L Sacco, Andrew C Steer, Imad M Tleyjeh, Mengru Wang, Kerrianne Watt, Martin Weinstock, Sarah Wulf, Pon-Hsiu Yeh, Patrícia Espíndola Mota Venâncio, Lisa C Rosenfeld, Uchechukwu Sampson, Sherine E. Gabriel, Andre Keren, Donald S Shepard, Robert Weintraub, Tim Driscoll, Joshua A Salomon, Thomas Truelsen
2012-05

Chronic hypobaric hypoxia mediated skeletal muscle atrophy: role of ubiquitin-proteasome pathway and calpains
2012-10-29

Genomic and proteomic profiling reveals reduced mitochondrial function and disruption of the neuromuscular junction driving rat sarcopenia

Steven P. Gygi
2012-05-07

Exercise training attenuates MuRF-1 expression in the skeletal muscle of patients with chronic heart failure independent of age: the randomized Leipzig Exercise Intervention in Chronic Heart Failure and Aging catabolism study

Jürgen Kratzsch, Joachim Thiery, Marcus Sandri, Irina Kozarez, Daniel Teupser, Sandra Erbs, Norman Mangner, Rainer Hambrecht, Gerhard Schuler
2012-03-05

Myostatin inhibition induces muscle fibre hypertrophy prior to satellite cell activation

Alexandra C McPherron
2011-01-24

Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models

Stefano Schiaffino

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