David Brough

শিক্ষালাভ করেছেন: ম্যানচেস্টার বিশ্ববিদ্যালয়, The Robert Gordon University

পেশা: গবেষক

Series

এখানে কিছুই নেই

নতুন সিরিজ তৈরি করুন

Works

এখানে কিছুই নেই

নতুন কাজ তৈরি করুন

নিবন্ধসমূহ 77

তারিখ

শিরোনাম

লেখকগণ

2021-02-17

Zinc Status Alters Alzheimer's Disease Progression through NLRP3-Dependent Inflammation

Víctor S Tapia, Claire S White, Shi Yu, জ্যাক গ্রিন, জেমস আর কুক, Ruth Peters, David Brough, ক্যাথরিন বি লরেন্স
2020-02-14

Haematopoietic stem cell gene therapy with IL-1Ra rescues cognitive loss in mucopolysaccharidosis IIIA

Claire O'Leary, David Brough, Emmanuel Pinteaux, Herve Boutin, Brian Bigger
2020-05-13

Gene Ontology Curation of Neuroinflammation Biology Improves the Interpretation of Alzheimer's Disease Gene Expression Data

Sandra Orchard, Maria-Jesus Martin, Barbara Kramarz, Paola Roncaglia, Helen Parkinson, David Brough, Ruth Lovering, Nigel Mark Hooper, Rachael Huntley, Rina Bandopadhyay
2020-05-23

Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture

David Brough
2020-09-20

Inhibition of the NLRP3 inflammasome by HSP90 inhibitors

David Brough
2020-11-03

Bafilomycin A1 enhances NLRP3 inflammasome activation in human monocytes independent of lysosomal acidification

জ্যাক গ্রিন, Gloria López-Castejón, David Brough
2020-11-04

Loss of hepatocyte cell division leads to liver inflammation and fibrosis

Matthew Richard Dewhurst, Jin Rong Ow, Noémi K Van Hul, Heike Wollmann, Xavier Bisteau, David Brough, Choi Hyungwon, Philipp Kaldis
2020-11-20

LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation

জ্যাক গ্রিন, Shi Yu, David Brough
2020-10-30

Co-design of a Smartphone App for People Living With Dementia by Applying Agile, Iterative Co-design Principles: Development and Usability Study (Preprint)

Matthew Machin, Adrian R Parry-Jones, Iracema Leroi, রিচার্ড ড্রেক, David Brough
2019-04-12

Cathelicidin is a "fire alarm", generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa

Brian J McHugh, Rongling Wang, Paula E Beaumont, Julia R Dorin, Emily Gwyer Findlay, David Brough, ডোনাল্ড জে ডেভিডসন
2019-04-02

The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes

Víctor S Tapia, Pablo Palazon-Riquelme, Matthew Richard Dewhurst, Jack Rivers-Auty, জ্যাক গ্রিন, Philipp Kaldis, David Brough, Michael Daniels, Gloria López-Castejón
2019-10-04

Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung

Alistair Chenery, Zainab Agha, James E Parkinson, মার্থা এম কুপার, Brian Chan, Ramon M. Eichenberger, Lindsay A Dent, Avril A.B. Robertson, David Brough, Tara E. Sutherland, Judith Allen, Paul R Giacomin
2018-02-05

Design, Synthesis and Evaluation of Oxazaborine Inhibitors of the NLRP3 Inflammasome.

Alex G. Baldwin, Víctor S Tapia, Claire S White, James A. Beswick, David Brough, Sally Freeman
2018-03-20

Redefining the ancestral origins of the interleukin-1 superfamily.

Jack Rivers-Auty, David Brough, Michael Daniels, ডেভিড এল রবার্টসন
2018-04-04

Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses

Alex G. Baldwin, David Brough, Elena Redondo-Castro, Michael J Haley
2018-09-19

Chloride regulates dynamic NLRP3-dependent ASC oligomerization and inflammasome priming

জ্যাক গ্রিন, Gloria López-Castejón, David Brough
2018-07-03

Is Targeting the Inflammasome a Way Forward for Neuroscience Drug Discovery?

জেমস আর কুক, James A. Beswick, David Brough
2018-10

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

জ্যাক গ্রিন, Gloria López-Castejón, David Brough, Pablo Palazon-Riquelme
2018-11-29

Improving the Gene Ontology Resource to Facilitate More Informative Analysis and Interpretation of Alzheimer’s Disease Data,Improving the Gene Ontology Resource to Facilitate More Informative Analysis and Interpretation of Alzheimer's Disease Data

Barbara Kramarz, Paola Roncaglia, Ruth Lovering, Sandra Orchard, Helen Parkinson, Maria-Jesus Martin, David Brough, Birgit H M Meldal, Rachael Huntley, Nigel Mark Hooper, Rina Bandopadhyay
2018-11-20

Small, Thin Graphene Oxide Is Anti-inflammatory Activating Nuclear Factor Erythroid 2-Related Factor 2 via Metabolic Reprogramming

Christopher Hoyle, Jack Rivers-Auty, Sandra Vranic, Kostas Kostarelos, David Brough, Nancy Rothwell
2017-01-05

Unconventional Pathways of Secretion Contribute to Inflammation

David Brough, Michael Daniels
2017-09-04

An emerging case for membrane pore formation as a common mechanism for the unconventional secretion of FGF2 and IL-1β.

David Brough
2016-02-12

Inflammasome-dependent IL-1β release depends upon membrane permeabilisation

Catherine Diamond, Alberto Baroja-Mazo, Michael Daniels, Alessandra Mortellaro, Pawel Paszek, David Brough, Pablo Pelegrín
2016-08-11

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models

Michael Daniels, Jack Rivers-Auty, Tom Schilling, William Watremez, Claire S White, Alex G. Baldwin, Shi Yu, Joshua Jackson, Stuart M. Allan, Pawel Paszek, ক্যাথরিন বি লরেন্স, David Brough
2016-12-23

Inflammasomes as therapeutic targets for Alzheimer's disease

Claire S White, Jack Rivers-Auty, ক্যাথরিন বি লরেন্স, David Brough
2016-08-02

Inflammasomes link vascular disease with neuroinflammation and brain disorders

David Brough
2016-08-25

P2X7 receptor-dependent tuning of gut epithelial responses to infection

Werner Müller, David Brough, Joanne Pennock, Kathryn J Else, Michael Daniels, Gloria López-Castejón, Sheena Cruickshank
2016-04-06

Brain injury induces specific changes in the caecal microbiota of mice via altered autonomic activity and mucoprotein production

David Brough
2016-12-23

Mini-symposium: Role of the inflammasome in brain pathogenesis: a potential therapeutic target? - introduction.

Delphine Boche, David Brough
2016-01-01

Investigating IL-1β Secretion Using Real-Time Single-Cell Imaging.

Pawel Paszek, David Brough, Catherine Diamond, Alessandra Mortellaro
2015-03-16

AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3.

Nikolett Lénárt, Pablo Pelegrín, David Brough, Sheena Cruickshank, Stuart M. Allan, Nancy Rothwell
2015-10-12

Inhibiting the Inflammasome: A Chemical Perspective

Alex G. Baldwin, David Brough

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