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CDK6 protects epithelial ovarian cancer from platinum-induced death via FOXO3 regulation

author

Gustavo Baldassarre

Maura Sonego

1978 -

Ilenia Pellarin

Vincenzo Canzonieri

Sara D'Andrea

Daniela Califano

Marina Bagnoli

Loredana Militello

Barbara Belletti

Monica Schiappacassi

Gennaro Chiappetta

Roberto Sorio

Sara Benevol

Alessandra Dall'Acqua

Ilenia Pellizzari

Joshua Armenia

published in: EMBO Molecular Medicine

date of publication: 2017-08-04

main subject: ovarian cancer

Cites articles 53

Date

Title

Authors

2017-08-02

Common biological phenotypes characterize the acquisition of platinum-resistance in epithelial ovarian cancer cells

Gustavo Baldassarre, Maura Sonego, Eliana Pivetta, Riccardo Bomben, Paola Spessotto, Valter Gattei, Barbara Belletti, Monica Schiappacassi, Roberto Sorio, Sara Benevol, Alessandra Dall'Acqua, Ilenia Pellizzari, Ilaria Lorenzon
2016-10-07

Niraparib Maintenance Therapy in Platinum-Sensitive, Recurrent Ovarian Cancer

Anne Dørum, Radosław Mądry, Domenica Lorusso, Ignace Vergote, Amit M Oza, Bradley J. Monk
2016-11-01

Biomarker analysis of the MITO2 phase III trial of first-line treatment in ovarian cancer: predictive value of DNA-PK and phosphorylated ACC

Gustavo Baldassarre, Delia Mezzanzanica, Domenica Lorusso, Stefano Indraccolo, Maria Gabriella Ferrandina, Maura Sonego, Elisabetta Zulato, Vincenzo Canzonieri, Daniela Califano, Giosuè Scognamiglio, Simona Losito, Giovanni Scambia, Antonella Savarese, Simona Signoriello, Roberto Sorio, Stefano Tamberi, Ciro Gallo, Sandro Pignata
2016-04-01

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases

Piotr Sicinski
2015-10-28

p27kip1 controls H-Ras/MAPK activation and cell cycle entry via modulation of MT stability

Ilenia Segatto, Sara D'Andrea, Riccardo Bomben, Monica Schiappacassi, Valter Gattei, Andrea Vecchione, Barbara Belletti, Gustavo Baldassarre, Linda Fabris, Ilenia Pellizzari, Joshua Armenia
2015-10-26

CDK6-a review of the past and a glimpse into the future: from cell-cycle control to transcriptional regulation
2015-10-08

SUMOylation regulates p27Kip1 stability and localization in response to TGFβ.

Barbara Belletti, Monica Schiappacassi, Sara Lovisa, Maura Sonego, Alfonso Colombatti, Gustavo Baldassarre, Alessandra Dall'Acqua, Valentina Ranzuglia
2015-06-01

Palbociclib in Hormone-Receptor-Positive Advanced Breast Cancer

Sibylle Loibl, Nadia Harbeck, Fabrice André, Sherene Loi, Hiroji Iwata, Massimo Cristofanilli
2015-04-15

The Role of CDK4/6 Inhibition in Breast Cancer
2015-02

Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis

Roland Schwarz, Florian Markowetz, Charlotte K Y Ng, James D Brenton, Helena Earl, Anna M Piskorz, Evis Sala
2015-01

The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study.

Igor N. Bondarenko
2015-05-01

Whole-genome characterization of chemoresistant ovarian cancer.

Richard W. Tothill, Angelika N Christ, Ronny Drapkin, Ravikiran Vedururu, Sean Grimmond, Dale W Garsed, Elizabeth L Christie, Jason Ellul, Gisela Mir Arnau, Peter J Bailey, Kathryn Alsop, Charlotte S Wilhelm-Benartzi, Paul Harnett, Anna deFazio, Heather Thorne, Nicola J Waddell, Ernst Lengyel, Australian Ovarian Cancer Study Group, David Bowtell, Michael A. Quinn, Prue A Cowin, Dariush Etemadmoghadam, Yoke-Eng Chiew, Euan A Stronach, Sian Fereday, Jillian Hung, Nadia Traficante, George Au-Yeung, Joy Hendley, Orla M McNally, Linda Mileshkin, Timothy Semple, Ann-Marie Patch, Walid J Azar, David K Miller
2014-01-01

Genetic characterization of p27(kip1) and stathmin in controlling cell proliferation in vivo

Sara D'Andrea, Ilenia Segatto, Vincenzo Canzonieri, Monica Schiappacassi, Valter Gattei, Alfonso Colombatti, Gustavo Baldassarre
2014-12-04

Olaparib combined with chemotherapy for recurrent platinum-sensitive ovarian cancer: a randomised phase 2 trial.

David Cibula, Gabe S Sonke, Barbara Schmalfeldt, Peter Vuylsteke
2014-04-21

Ovarian cancer

Gordon C. Jayson
2013-09-01

DNA damage sensing by the ATM and ATR kinases

Alexandre Maréchal
2013-08-12

A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis

Dontscho Kerjaschki, Gerwin Heller, Sabine Zöchbauer-Müller, Marcos Malumbres, Christoph Bock, Richard Moriggl, Meinrad Busslinger, Lukas Kenner, Gerald Hoefler, Anthony R Green, Michael Freissmuth, Veronika Sexl
2013-05-22

A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis

Maura Sonego, Barbara Belletti, Gustavo Baldassarre, Andrea Vecchione, Antonella Stoppacciaro, Sandro Pignata, Stefano Volinia, Carlo Maria Croce, Daniela Califano, Hansjuerg Alder, Gennaro Chiappetta, Vincenzo Canzonieri, Roberto Sorio, Simona Losito, Francesca Lovat
2013-05-06

Signaling through cyclin D-dependent kinases
2013-04-22

Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer

Maura Sonego, Monica Schiappacassi, Sara Lovisa, Marina Bagnoli, Massimo Libra, Sara D'Andrea, Vincenzo Canzonieri, Loredana Militello, Marco Napoli, Giorgio Giorda, Delia Mezzanzanica, Barbara Valeri, Alfonso Colombatti, Barbara Belletti, Giannino Del Sal, Gustavo Baldassarre, Alessandra Dall'Acqua
2013-04-17

Regulation of the DNA damage response by cyclin-dependent kinases

Maria Pia Longhese
2013-04-08

Phase II trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified well-differentiated or dedifferentiated liposarcoma

Jonathan Landa, Aimee M Crago, Samuel Singer, Sandra P D'Angelo
2013-04-01

Precursors and pathogenesis of ovarian carcinoma
2012-10-01

The requirement for cyclin D function in tumor maintenance

Harald von Boehmer, Takaomi Sanda, A. Thomas Look, Piotr Sicinski
2012-05-17

Selective CDK4/6 inhibition with tumor responses by PD0332991 in patients with mantle cell lymphoma

Jeffrey Yap, Keith D Wilner, Ann S LaCasce
2012-02-01

Multiple roles of cyclin-dependent kinase 4/6 inhibitors in cancer therapy

Charles M. Perou, Norman Sharpless, Kwok Kin Wong, David B Darr, Austin J Combest, Jerry E Usary
2011-11-15

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells

Pascal Braun, Hans R. Widlund, Marc Vidal, Piotr Sicinski
2011-10-25

Chromatin immunoprecipitation (ChIP): revisiting the efficacy of sample preparation, sonication, quantification of sheared DNA, and analysis via PCR.

Brian R Wamhoff
2011-07-01

Physiological relevance of cell cycle kinases

Marcos Malumbres
2011-06-29

Integrated genomic analyses of ovarian carcinoma

Cancer Genome Atlas Research Network, William Schierding
2011-03-15

Expression of p16 and retinoblastoma determines response to CDK4/6 inhibition in ovarian cancer

Victor Velculescu, Charles Ginther, Judy Dering, Boris Winterhoff, Meenal Chalukya, Kanthinh Manivong, Siân Jones, Lynn C. Hartmann, Kimberly R Kalli, Gottfried E Konecny, William A Cliby, Dennis Slamon
2010-11-01

Cyclin-dependent kinases (cdks) and the DNA damage response: rationale for cdk inhibitor-chemotherapy combinations as an anticancer strategy for solid tumors

Article - wd:Q38639827

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