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Apolipoprotein CI enhances the biological response to LPS via the CD14/TLR4 pathway by LPS-binding elements in both its N- and C-terminal helix

author

Claudia P Coomans

Patrick Rensen

published in: Journal of Lipid Research

date of publication: 2010-03-24

main subject: toll-like receptor

Cites articles 47

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Infection induces a positive acute phase apolipoprotein E response from a negative acute phase gene: role of hepatic LDL receptors
2008-04-12

Preoperative apolipoprotein CI levels correlate positively with the proinflammatory response in patients experiencing endotoxemia following elective cardiac surgery

Louis M Havekes
2008-02-01

Plasma apolipoprotein CI protects against mortality from infection in old age

Simon P. Mooijaart, Patrick Rensen, Rudi Westendorp, Jimmy F P Berbée, Diana van Heemst, Anton J M de Craen
2008-01-30

Plasma apolipoprotein CI correlates with increased survival in patients with severe sepsis

Louis M Havekes
2007-10-22

Apolipoprotein C-I is crucially involved in lipopolysaccharide-induced atherosclerosis development in apolipoprotein E-knockout mice

Nuno Miguel Pires, Patrick Rensen
2006-05-01

Regulatory roles for MD-2 and TLR4 in ligand-induced receptor clustering
2006-03-30

Scavenger receptor BI prevents nitric oxide-induced cytotoxicity and endotoxin-induced death.
2006-08-25

Apolipoprotein CI stimulates the response to lipopolysaccharide and reduces mortality in gram-negative sepsis

Patrick Rensen
2005-10-06

Apolipoprotein-mediated pathways of lipid antigen presentation

D. Branch Moody, Peter van den Elzen, Gurdyal Besra
2005-02

Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL

Louis M Havekes
2004-06-15

Targeting of scavenger receptor class B type I by synthetic amphipathic alpha-helical-containing peptides blocks lipopolysaccharide (LPS) uptake and LPS-induced pro-inflammatory cytokine responses in THP-1 monocyte cells

Tatyana G Vishnyakova, Alan T. Remaley
2003-05-01

Proinflammatory cytokines and sepsis syndrome: not enough, or too much of a good thing?

Mihai Netea, Bart Jan Kullberg, Jos van der Meer
2003-06-20

Binding and internalization of lipopolysaccharide by Cla-1, a human orthologue of rodent scavenger receptor B1

Tatyana G Vishnyakova, Alan T. Remaley
2003-12-01

The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor

Ole E Sorensen, Niels Borregaard
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APOE Genotype and an ApoE-mimetic Peptide Modify the Systemic and Central Nervous System Inflammatory Response

Michael P Vitek
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SMAP-29 has two LPS-binding sites and a central hinge

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Essential role of MD-2 in LPS responsiveness and TLR4 distribution.

Yoichiro Iwakura
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Identification of LPS-binding peptide fragment of MD-2, a toll-receptor accessory protein

Primož Pristovšek, Roman Jerala
2001-10-01

Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice
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ApoE-containing high density lipoproteins and phospholipid transfer protein activity increase in patients with a systemic inflammatory response
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Interpretation of biological activity data of bacterial endotoxins by simple molecular models of mechanism of action
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MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
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Lipopolysaccharide (LPS)-binding synthetic peptides derived from serum amyloid P component neutralize LPS.
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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene,Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene

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Lactoferrin inhibits the endotoxin interaction with CD14 by competition with the lipopolysaccharide-binding protein
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The macrophage scavenger receptor type A is expressed by activated macrophages and protects the host against lethal endotoxic shock
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Crystal structure of human BPI and two bound phospholipids at 2.4 angstrom resolution
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Sepsis: a new hypothesis for pathogenesis of the disease process
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Particle size determines the specificity of apolipoprotein E-containing triglyceride-rich emulsions for the LDL receptor versus hepatic remnant receptor in vivo
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Article - wd:Q39723291

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