Michal Hocek

1969 -

写真のクレジット： Wikimedia Commons

使用可能言語: チェコ語

Michal Hocek (* 11. prosince 1969 v Benešově, Československo) je český vědec působící na ÚOCHB AVČR a profesor organické chemie na Univerzitě Karlově v Praze, který se specializuje na chemii a biologii nukleosidů, nukleotidů a nukleových kyselin. Source: Wikipedia (cs)

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記事 143

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2021-01-04

Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses

Daniel Růžek, Radim Nencka, Evzen Boura, Michal Hocek
2020-01-09

Tuning of Oxidation Potential of Ferrocene for Ratiometric Redox Labeling and Coding of Nucleotides and DNA

Ivan Magriñá, Veronika Raindlová, Miroslav Fojta, Ciara O' Sullivan, Michal Hocek
2020-01-01

2-Substituted 2'-deoxyinosine 5'-triphosphates as substrates for polymerase synthesis of minor-groove-modified DNA and effects on restriction endonuclease cleavage

Michal Hocek
2020-01-10

Thiophene-linked tetramethylbodipy-labeled nucleotide for viscosity-sensitive oligonucleotide probes of hybridization and protein-DNA interactions

Michal Hocek, Piotr Jurkiewicz
2020-06-01

2-Formyl-dATP as Substrate for Polymerase Synthesis of Reactive DNA Bearing an Aldehyde Group in the Minor Groove

Michal Hocek, Lenka Poštová Slavětínská
2020-11-06

Photocaged 5-(Hydroxymethyl)pyrimidine Nucleoside Phosphoramidites for Specific Photoactivatable Epigenetic Labeling of DNA

Michal Hocek
2019-01-25

Correction to "Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides"

Anna Tokarenko, Michal Tichý, Pavla Perlíková, Ivo Frydrych, Marián Hajdúch, Michal Hocek, Soňa Gurská, Eva Tloušt'ová, Pawel Znojek, Lenka Poštová Slavětínská, Barbora Lišková, Radek Pohl, Blanka Klepetářová, Noor-Ul-Ain Khalid, Yiqian Wenren, Rebecca R. Laposa, Petr Dzubak, Sabina Smoleń, Natálie Táborská
2019-03-04

Switching transcription with bacterial RNA polymerase through photocaging, photorelease and phosphorylation reactions in the major groove of DNA

Martina Janoušková, Libor Krasny, Michal Hocek
2019-12-19

Oxidative DNA Cleavage with Clip-Phenanthroline Triplex-Forming Oligonucleotide Hybrids

Michal Hocek
2019-08-13

Squaramate-Modified Nucleotides and DNA for Specific Cross-Linking with Lysine-Containing Peptides and Proteins

Ivana Ivancová, Michal Hocek
2019-12-11

Duplex Electrochemical DNA Sensor to Detect Bacillus anthracis CAP and PAG DNA Targets Based on the Incorporation of Tailed Primers and Ferrocene-Labeled dATP

Michal Hocek
2019-06-05

Enzymatic Synthesis of Base-Functionalized Nucleic Acids for Sensing, Cross-linking, and Modulation of Protein-DNA Binding and Transcription

Michal Hocek
2019-08-13

Vicinal Diol-Tethered Nucleobases as Targets for DNA Redox Labeling with Osmate Complexes

Michal Hocek
2019-03-30

Electrochemical genosensor for the direct detection of tailed PCR amplicons incorporating ferrocene labelled dATP

Michal Hocek
2018-11-02

Brightly Fluorescent 2'-Deoxyribonucleoside Triphosphates Bearing Methylated Bodipy Fluorophore for in Cellulo Incorporation to DNA, Imaging, and Flow Cytometry

Dmytro Dziuba, Tomas Kraus, Michal Hocek
2018-06-19

Synthesis of Dihydroxyalkynyl and Dihydroxyalkyl Nucleotides as Building Blocks or Precursors for Introduction of Diol or Aldehyde Groups to DNA for Bioconjugations

Michal Hocek
2018-06-13

Flexible Alkyne-Linked Thymidine Phosphoramidites and Triphosphates for Chemical or Polymerase Synthesis and Fast Postsynthetic DNA Functionalization through Copper-Catalyzed Alkyne-Azide 1,3-Dipolar Cycloaddition

Alessandro Panattoni, Michal Hocek
2018-08-01

Protected 2'-deoxyribonucleoside triphosphate building blocks for the photocaging of epigenetic 5-(hydroxymethyl)cytosine in DNA

Michal Hocek, Lenka Poštová Slavětínská
2018-08-01

Enzymatic synthesis of base-modified RNA by T7 RNA polymerase. A systematic study and comparison of 5-substituted pyrimidine and 7-substituted 7-deazapurine nucleoside triphosphates as substrates

Pavla Perlíková, Michal Hocek
2018-10-26

Dual redox labeling of DNA as a tool for electrochemical detection of p53 protein-DNA interactions

Michal Hocek
2018-04-27

C-H Imidation of 7-Deazapurines

Michal Hocek, Lenka Poštová Slavětínská
2018-09-06

2-Allyl- and Propargylamino-dATPs for Site-Specific Enzymatic Introduction of a Single Modification in the Minor Groove of DNA

Michal Hocek
2018-02-12

Protected 5-(hydroxymethyl)uracil nucleotides bearing visible-light photocleavable groups as building blocks for polymerase synthesis of photocaged DNA.

Petr Klán, Michal Hocek, Lenka Poštová Slavětínská
2018-05-17

Turning Off Transcription with Bacterial RNA Polymerase through CuAAC Click Reactions of DNA Containing 5-Ethynyluracil

Hana Cahová, Michal Hocek
2018-10-03

Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-fused 7-Deazapurine Ribonucleosides,Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides

Soňa Gurská, Marián Hajdúch, Michal Tichý, Pavla Perlíková, Michal Hocek, Ivo Frydrych, Eva Tloušt'ová, Pawel Znojek, Lenka Poštová Slavětínská, Barbora Lišková, Radek Pohl, Blanka Klepetářová, Noor-Ul-Ain Khalid, Yiqian Wenren, Rebecca R. Laposa, Petr Dzubak, Sabina Smoleń, Natálie Táborská
2017-03-03

Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides

Michal Tichý, Sabina Smoleń, Radek Pohl, Tomás Ozdian, Barbora Lišková, Petr Dzubak, Marián Hajdúch, Michal Hocek, Soňa Gurská, Eva Tloušt'ová
2017-06-27

Strategies toward protecting group-free glycosylation through selective activation of the anomeric center

Michal Hocek
2017-08-23

Pyrrolo[2,3-d]pyrimidine (7-deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides

Michal Hocek, Pavla Perlíková
2017-10-09

Trifluoroacetophenone-Linked Nucleotides and DNA for Studying of DNA-Protein Interactions by 19F NMR Spectroscopy.

Michal Hocek, Radek Pohl
2017-01-23

Synthesis of Nucleosides through Direct Glycosylation of Nucleobases with 5-O-Monoprotected or 5-Modified Ribose: Improved Protocol, Scope, and Mechanism.

Michal Hocek, Radek Pohl, Jana Roithová
2017-12-01

5-(Hydroxymethyl)uracil and -cytosine as potential epigenetic marks enhancing or inhibiting transcription with bacterial RNA polymerase

Michal Hocek
2017-08-09

Phenothiazine-linked nucleosides and nucleotides for redox labelling of DNA.

Michal Hocek, Luděk Havran, Radek Pohl

Human - wd:Q39952925

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