Honglin Chen

заклад освіти: Гонконзький університет

рід діяльності: дослідник

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Статті 125

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Автори

2022-01-03

Immunogenicity of a Heterologous Prime-Boost COVID-19 Vaccination with mRNA and Inactivated Virus Vaccines Compared with Homologous Vaccination Strategy against SARS-CoV-2 Variants

Ruiqi Zhang, Honglin Chen, Kwok-Hung Chan, Ivan Fan Ngai Hung
2020-04-17

Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction

Zhiwei Chen, Honglin Chen, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Юень Куок Юн, Hin Chu, Pui Wang, Wenjun Song, Siu-Ying Lau, Andrew C Y Lee, Bobo Wing-Yee Mok, Shaofeng Deng
2020-05-13

Infection of bat and human intestinal organoids by SARS-CoV-2

Jie Zhou, Man Chun Chiu, Xiaoyu Zhao, Andrew C Y Lee, Kenneth K Y Wong, Kwok-Hung Chan, Honglin Chen, Юень Куок Юн, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Cyril Chik-Yan Yip, Jian-Piao Cai, Owen Tak-Yin Tsang, Hin Chu, Ivy Hau-Yee Chan
2020-08-28

Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target

Shuofeng Yuan, Hin Chu, Jingjing Huang, Xiaoyu Zhao, Zi-Wei Ye, Pok Man Lai, Lei Wen, Jian-Piao Cai, Yufei Mo, Jianli Cao, Ronghui Liang, Vincent Kwok-Man Poon, Kong-Hung Sze, Jie Zhou, Kelvin Kai-Wang To, Zhiwei Chen, Honglin Chen, Dong-Yan Jin, Jasper Fuk-Woo Chan, Kwok-Yung Yuen
2019-03-22

The PB2 Polymerase Host Adaptation Substitutions Prime Avian Indonesia Sub Clade 2.1 H5N1 Viruses for Infecting Humans

Honglin Chen
2019-09-17

Generation of DelNS1 Influenza Viruses: a Strategy for Optimizing Live Attenuated Influenza Vaccines

Kelvin Kai-Wang To, Honglin Chen
2018-03-06

Low population serum microneutralization antibody titer against the predominating influenza A(H3N2) N121K virus during the severe influenza summer peak of Hong Kong in 2017

Honglin Chen, Ivan Fan Ngai Hung, Юень Куок Юн, Kelvin Kai-Wang To, Rosana Wing-Shan Poon, Sidney Tam, Houshun Zhu, Winger Wing-Nga Mak, Joy-Yan Lam
2018-03-07

Rapid detection of MERS coronavirus-like viruses in bats: pote1ntial for tracking MERS coronavirus transmission and animal origin

Honglin Chen, P C Woo, Susanna Kar-Pui Lau, Юень Куок Юн
2018-04-16

NF-κB Signaling Regulates Epstein-Barr Virus BamHI-Q-Driven EBNA1 Expression

Honglin Chen, Jianji Pan
2018-03-29

Large-scale sequence analysis reveals novel human-adaptive markers in PB2 segment of seasonal influenza A viruses

Yan-Hui Fan, Honglin Chen, Hin Chu, Man Chun Chiu, Shuofeng Yuan, Jie Zhou, Юень Куок Юн
2018-06-11

Differentiated human airway organoids to assess infectivity of emerging influenza virus

Jie Zhou, Man Chun Chiu, Hin Chu, Jasper Fuk-Woo Chan, Kelvin Kai-Wang To, Honglin Chen, Юень Куок Юн, Ганс Клеверс, Shuofeng Yuan, Wenjun Song, Bosco Ho-Yin Wong, Kenneth Kak-Yuen Wong
2018-11-07

Establishment and characterization of new tumor xenografts and cancer cell lines from EBV-positive nasopharyngeal carcinoma

Weitao Lin, Sai Wah Tsao, Lin Jia, Hong Zheng, Wei Dai, Josephine Ko, Kwok Wai Lo, Kevin Y Yip, Jun Zhang, Pierre Busson, Xuefeng Liu, Siu Tim Cheung, Jaap M Middeldorp, Honglin Chen
2018-11-26

EBV-miR-BART8-3p induces epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma cells through activating NF-κB and Erk1/2 pathways

Honglin Chen, Jianji Pan
2018-08-16

Structural Basis for the Broad, Antibody-Mediated Neutralization of H5N1 Influenza Virus

Honglin Chen, Xia Ningshao, Shaowei Li
2017-10-01

A multimechanistic antibody targeting the receptor binding site potently cross-protects against influenza B viruses

Honglin Chen, Chenguang Shen, Jianli Cao, Stephen F Anderson, Timothy Alefantis, Hai Yu, Yixin Chen, Xia Ningshao, Jun Zhang
2017-03-21

An NS-segment exonic splicing enhancer regulates influenza A virus replication in mammalian cells

Юень Куок Юн, Honglin Chen
2016-03-15

Human H7N9 virus induces a more pronounced pro-inflammatory cytokine but an attenuated interferon response in human bronchial epithelial cells when compared with an epidemiologically-linked chicken H7N9 virus.

Kwok-Hung Chan, Юень Куок Юн, Honglin Chen, Kelvin Kai-Wang To, Patrick C Y Woo, Susanna K P Lau, Jasper Fuk-Woo Chan, Candy Choi-Yi Lau
2016-04-12

Hemagglutinin amino acids related to receptor specificity could affect the protection efficacy of H5N1 and H7N9 avian influenza virus vaccines in mice.

Honglin Chen, Peter Pushko, Chuan Qin, Linlin Bao
2016-06-02

Mycophenolic acid, an immunomodulator, has potent and broad-spectrum in vitro antiviral activity against pandemic, seasonal and avian influenza viruses affecting humans

Kwok-Hung Chan, Юень Куок Юн, Honglin Chen, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Richard Kao, Pui Wang, Yin-Ming Lui
2016-08-18

Complete Genome Sequence of Influenza Virus H9N2 Associated with a Fatal Outbreak among Chickens in Dubai

Honglin Chen, Patrick C Y Woo, Susanna Kar-Pui Lau, Ulrich Wernery
2016-12-01

Preclinical evaluation of the safety and pathogenicity of a live attenuated recombinant influenza A/H7N9 seed strain and corresponding MF59-adjuvanted split vaccine

Honglin Chen
2016-04-13

Hemagglutinin of influenza A virus binds specifically to cell surface nucleolin and plays a role in virus internalization

Anna Jinxia Zhang, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Honglin Chen, Юень Куок Юн, Dong-Yan Jin, Kenn Ka-Heng Chik, Richard Yi-Tsun Kao, Hin Chu, Kong-Hung Sze, Che-Man Chan
2016-11-22

Efficacy of Clarithromycin-Naproxen-Oseltamivir Combination in the Treatment of Patients Hospitalized for Influenza A(H3N2) Infection: An Open-label Randomized, Controlled, Phase IIb/III Trial

Ivan Fan Ngai Hung, Kelvin Kai-Wang To, Ka-Shing Cheung, Chun-Yin William Leung, Honglin Chen, Юень Куок Юн, Jasper Fuk-Woo Chan, Vincent J. Cheng, Ricky Zhang, Tuen-Ching Chan, Tin-Lun Wong, Johnson Y N Lau
2016-02-22

MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2

Man-Lung Yeung, Honglin Chen, Kelvin Kai-Wang To, Hin Chu, Jie Zhou, P C Woo, S Yung, Dong-Yan Jin, Юень Куок Юн, Susanna K P Lau, Jasper Fuk-Woo Chan, Peter Mathieson, Jade L.L. Teng, Alan K L Tsang, Johnson Y N Lau, Yanfeng Yao, Lilong Jia
2015

The Therapeutic Effect of Pamidronate on Lethal Avian Influenza A H7N9 Virus Infected Humanized Mice

Jasper Fuk-Woo Chan, Kwok-Hung Chan, Юень Куок Юн, Kelvin Kai-Wang To, Honglin Chen, Siu-Ying Lau, Winnie Wai Lan Chan
2015-10-07

Suboptimal Humoral Immune Response against Influenza A(H7N9) Virus Is Related to Its Internal Genes

Honglin Chen, Ivan Fan Ngai Hung, Kelvin Kai-Wang To, Юень Куок Юн, Houshun Zhu, Pui Wang
2015-01-31

Cross-species transmission and emergence of novel viruses from birds

Jasper Fuk-Woo Chan, Kelvin Kai-Wang To, Honglin Chen, Юень Куок Юн
2015-09-07

Outbreaks of highly pathogenic avian influenza H5N1 clade 2.3.2.1c in hunting falcons and kept wild birds in Dubai implicate intercontinental virus spread

Timm C Harder, Honglin Chen, Martin Beer, Patrick C Y Woo, Renate Wernery, Ulrich Wernery
2015-11-06

Topical imiquimod before intradermal trivalent influenza vaccine for protection against heterologous non-vaccine and antigenically drifted viruses: a single-centre, double-blind, randomised, controlled phase 2b/3 trial

Kelvin Kai-Wang To, Honglin Chen, Jasper Fuk-Woo Chan, Юень Куок Юн, Anna Jinxia Zhang, Ivan Fan Ngai Hung, Ricky Zhang, Tuen-Ching Chan, Tin-Lun Wong, Johnson Y N Lau
2015-08-12

Severe Acute Respiratory Syndrome (SARS) Coronavirus ORF8 Protein Is Acquired from SARS-Related Coronavirus from Greater Horseshoe Bats through Recombination

Jasper Fuk-Woo Chan, Susanna Kar-Pui Lau, Honglin Chen, Hayes K H Luk, Wang-Ngai Chow, Юень Куок Юн, P C Woo, Jian-Piao Cai, Samson S Y Wong, Syed Shakeel Ahmed, Hazel C Yeung, Hai-Lin Zhang
2015-07-21

Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset

Jasper Fuk-Woo Chan, Man-Lung Yeung, Honglin Chen, Hin Chu, Jie Zhou, Юень Куок Юн, Chuan Qin, Linlin Bao, Wei Deng, Jian-Piao Cai, Yanfeng Yao, Lilong Jia
2015-01-24

Recombinant influenza A virus hemagglutinin HA2 subunit protects mice against influenza A(H7N9) virus infection

Honglin Chen, Kelvin Kai-Wang To, Юень Куок Юн, Candy Choi-Yi Lau, Winnie Wai Lan Chan, Chuan-Gen Lin, Jian-Piao Cai, Akhee S Jahan

Human - wd:Q41524644

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