Gaynor A Smith

educated at: Cardiff University

occupation: researcher

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Articles 24

Date

Title

Authors

2019-05-14

Glutathione S-Transferase Regulates Mitochondrial Populations in Axons through Increased Glutathione Oxidation

Gaynor A Smith, Lukas J Neukomm
2016-11-15

Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson's disease

Ludivine S Breger, Gaynor A Smith, Stephen Dunnett, Emma L. Lane
2015-10-01

Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons

Gaynor A Smith, Penelope J. Hallett, Ole Isacson
2015-03-27

A Nurr1 agonist causes neuroprotection in a Parkinson's disease lesion model primed with the toll-like receptor 3 dsRNA inflammatory stimulant poly(I:C).

Gaynor A Smith, Penelope J. Hallett, Ole Isacson
2015-02-06

Progressive decline of glucocerebrosidase in aging and Parkinson's disease

Gaynor A Smith, Penelope J. Hallett, Ole Isacson
2015-02-26

Successful function of autologous iPSC-derived dopamine neurons following transplantation in a non-human primate model of Parkinson's disease

Penelope J. Hallett, Gaynor A Smith, Oliver Cooper, Maria Sundberg, Ole Isacson
2015-06-21

Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice

Gaynor A Smith, Penelope J. Hallett, Ole Isacson
2015-09-23

Fibroblast Biomarkers of Sporadic Parkinson's Disease and LRRK2 Kinase Inhibition

Gaynor A Smith, Penelope J. Hallett, Ole Isacson
2015-08-01

Using Drosophila models of Huntington's disease as a translatable tool

Gaynor A Smith
2014-06-04

ALS-associated peripherin spliced transcripts form distinct protein inclusions that are neuroprotective against oxidative stress

Gaynor A Smith, Penelope J. Hallett, Ole Isacson
2014-05-29

Widespread neuron-specific transgene expression in brain and spinal cord following synapsin promoter-driven AAV9 neonatal intracerebroventricular injection

Gaynor A Smith, Penelope J. Hallett, Ole Isacson
2014-04-12

Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington's disease

Gaynor A Smith, Penelope J. Hallett, Ole Isacson
2013-01-01

Chronic administration of Dimebon does not ameliorate amyloid-β pathology in 5xFAD transgenic mice

Owen M Peters, Michail Kukharsky, Gaynor A Smith, Sergey Kozin, Yuri Kotelevtsev, Vladimir Buchman
2013-12-31

Enhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease

Penelope J. Hallett, Thomas G Moens, Gaynor A Smith, Ole Isacson, George K Tofaris
2013-07-12

Two cells are better than one: optimizing stem cell survival by co-grafting "helper" cells that offer regulated trophic support.

Gaynor A Smith, Evan Y Snyder
2012-07-14

The search for genetic mouse models of prodromal Parkinson's disease

Gaynor A Smith, Ole Isacson, Stephen Dunnett
2012-01-01

Amphetamine-induced dyskinesia in the transplanted hemi-Parkinsonian mouse

Gaynor A Smith, Andreas Heuer, Stephen Dunnett, Emma L. Lane
2012-11-01

Comparison of 6-hydroxydopamine lesions of the substantia nigra and the medial forebrain bundle on a lateralised choice reaction time task in mice

Gaynor A Smith, Stephen Dunnett, Andreas Heuer
2012-04-09

Amphetamine-induced rotation in the transplanted hemi-parkinsonian rat--response to pharmacological modulation.

Gaynor A Smith, Stephen Dunnett, Emma L. Lane
2012-06-18

Pharmacological modulation of amphetamine-induced dyskinesia in transplanted hemi-parkinsonian rats

Gaynor A Smith, Emma L. Lane, Stephen Dunnett, Ludivine S Breger
2011-06-23

Increased efficacy of the 6-hydroxydopamine lesion of the median forebrain bundle in small rats, by modification of the stereotaxic coordinates

Emma L. Lane, Andreas Heuer, Gaynor A Smith, Stephen Dunnett
2011-01-08

Context-driven changes in L-DOPA-induced behaviours in the 6-OHDA lesioned rat

Gaynor A Smith, Stephen Dunnett, Emma L. Lane
2011-09-19

Unilateral nigrostriatal 6-hydroxydopamine lesions in mice II: predicting l-DOPA-induced dyskinesia.

Gaynor A Smith, Andreas Heuer, Stephen Dunnett, Emma L. Lane
2010-09-01

Understanding graft-induced dyskinesia

Emma L. Lane, Gaynor A Smith

Human - wd:Q42215544

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