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Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing.

Autor

Olav M. Andersen

Camilla Gustafsen

Peder Madsen

Thomas E Willnow

veröffentlicht in: Journal of Neuroscience

Erscheinungsdatum: 2012-01-01

Sprache: Englisch

Zitiert Artikel 50

Datum

Titel

Autor

2010-04-12

SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na(+)-K(+)-Cl(-) cotransporter 2.

David H. Ellison, Michael Bader, Anders Nykjaer, Mihail Todiras, Thomas E Willnow
2010-09-01

Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex

Rudolph E. Tanzi
2010-10-05

The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics

Evan Reid
2010-10-11

Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated

Sandra I. Vieira, Sandra Rebelo, Jens Wiltfang
2010-03-01

Retromer-mediated direct sorting is required for proper endosomal recycling of the mammalian iron transporter DMT1
2009-11-10

GGA autoinhibition revisited

Camilla Gustafsen, Cristiano L.P. Oliveira, Jan Skov Pedersen, Peder Madsen, Søren Skou Thirup
2008-08

Retromer
2008-05-20

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation

Karen Duff, Ottavio Arancio, Barry Ganetzky
2008-11-01

Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease

Olav M. Andersen, Thomas E Willnow
2008-06-07

The structure and function of the retromer protein complex

Brett M. Collins
2008-03

Structure of Vps26B and mapping of its interaction with the retromer protein complex

Brett M. Collins, Rohan D. Teasdale
2008-11-14

Trafficking, a key player in regulated intramembrane proteolysis
2008-11-12

VPS10P-domain receptors - regulators of neuronal viability and function

Thomas E Willnow, Anders Nykjaer
2008-05-23

Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesis

Christian Wozny, Susanne Wolf, Gerd Kempermann
2008-09-01

Endosome protein sorting: motifs and machinery
2007-07-23

Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA.

Oddmund Bakke, Guido Hermey, Peder Madsen
2007-09-12

SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1

Olav M. Andersen, Thomas E Willnow
2007-02

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

Christian Haass, Dennis J. Selkoe
2007-07-01

Identification of a novel conserved sorting motif required for retromer-mediated endosome-to-TGN retrieval
2007-06-01

The retromer complex and clathrin define an early endosomal retrograde exit site

Juan S. Bonifacino, Ludger Johannes, Christophe Lamaze, Graça Raposo
2007-02

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

Ekaterina Rogaeva, Peter Henry St George-Hyslop, Gerold Schmitt-Ulms, Olav M. Andersen, Rivka Inzelberg, Thomas E Willnow, Clinton Baldwin, Joseph H. Lee, Kathryn L. Lunetta, Sandro Sorbi, Lindsay A. Farrer, Dennis W. Dickson, Robert C. Green, Richard Mayeux, Toshitaka Kawarai, Ronald C. Petersen, L. Adrienne Cupples, Neill R Graff-Radford, Amalia Bruni, Innocenzo Rainero, Lorenzo Pinessi, Yosuke Wakutani, Christopher Bohm, Taiichi Katayama, Nobuto Shibata, Ranjan Duara, Fanggeng Zou, Robert P Friedland, You-Qiang Song, Steven G. Younkin
2007-12-17

AP-1 and retromer play opposite roles in the trafficking of sortilin between the Golgi apparatus and the lysosomes
2007-01-01

A loss-of-function screen reveals SNX5 and SNX6 as potential components of the mammalian retromer

Naomi Attar, Peter J Cullen
2006-10-29

Direct observation of individual endogenous protein complexes in situ by proximity ligation

Ola Söderberg, Mats Gullberg
2006-02-01

The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments
2006-09-01

LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease

Thomas J Montine
2006-02-01

Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11.

Olav M. Andersen, Michael W Parker, Roberto Cappai, William J McKinstry, Thomas E Willnow, Colin L. Masters, Bradley Hyman
2006-10-01

Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis
2006-05-28

The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain

Juan S. Bonifacino
2006-08-01

Retrograde transport from endosomes to the trans-Golgi network

Juan S. Bonifacino
2005-09-07

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

Tilman Breiderhoff, Olav M. Andersen, Michael Gotthardt, Thomas E Willnow, Anders Nykjaer, Roberto Cappai, Colin L. Masters, Bradley Hyman
2005-10-01

Sorting nexin-2 is associated with tubular elements of the early endosome, but is not essential for retromer-mediated endosome-to-TGN transport

Judith Klumperman, Viola Oorschot, Jeremy G Carlton, Peter J Cullen

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