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Alzheimer disease: modeling an Aβ-centered biological network.

autore

Gael Nicolas

1984 -

Kilan Le Guennec

1989 -

pubblicato in: Molecular Psychiatry

data di pubblicazione: 2016-03-29

lingua: inglese

argomento principale: malattia di Alzheimer

Cita articoli 179

Data

Titolo

Autori

2015-06

Three dimensions of the amyloid hypothesis: time, space and 'wingmen'

David M. Holtzman
2015-07-21

De novo deleterious genetic variations target a biological network centered on Aβ peptide in early-onset Alzheimer disease

Premendu Prakash Mathur, Gael Nicolas, Pranitha Jenardhanan, Kilan Le Guennec
2015-03-01

Innate immunity in Alzheimer's disease

Douglas T Golenbock
2015-04-01

Neuroinflammation in Alzheimer's disease

Bente Finsen, Alexei Verkhratsky, Koji Yamanaka, Stéphane Hunot, Olga Garaschuk, Charles A. Dinarello, Guy Brown, Tony Wyss-Coray, Douglas T Golenbock, Richard M Ransohoff, Terrence Town, Sally A Frautschy
2015-02-26

TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model

Susan Gilfillan, Marco Colonna, David M. Holtzman
2015-03-25

Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease

Srdjan Djurovic, Hrefna Johannsdottir, Hilkka Soininen, Hreinn Stefansson, Lars T. Westlye, Dag Aarsland, Harald Hampel, Augustine Kong, Ole A. Andreassen, Geir Selbæk, Patrick Sulem, Kári Stefánsson, Ina Giegling, Dan Rujescu, Tormod Fladby, James J Lah, Stacy Steinberg, Jon Snaedal, Thorlakur Jonsson, Allan Levey, Ingun D. Ulstein, Andrés Ingason, Sigrid B Sando, Sigurjon A Gudjonsson, Gun Peggy Knudsen
2015-08-10

ATP-binding cassette transporter A7 (ABCA7) loss of function alters Alzheimer amyloid processing

Peter St George-Hyslop
2015-06-01

The case for rejecting the amyloid cascade hypothesis

Karl Herrup
2015-08-25

SORL1 rare variants: a major risk factor for familial early-onset Alzheimer's disease

Céline Bellenguez, Richard Redon, Jean-Charles Lambert, Kilan Le Guennec, Philippe Amouyel, Luc Letenneur, Emmanuelle Génin, Mark Lathrop, Benjamin Grenier-Boley, CNR-MAJ collaborators, Anne Rovelet-Lecrux, Jean-François Dartigues
2014-11-06

Frontotemporal dementia with parkinsonism linked to chromosome 17 with the MAPT R406W mutation presenting with a broad distribution of abundant senile plaques.
2014-04-01

Amyloid-β and tau: the trigger and bullet in Alzheimer disease pathogenesis
2014-11-13

The contribution of de novo coding mutations to autism spectrum disorder

Jay Shendure, Evan E. Eichler, Holly A Stessman, Brian J O'Roak, Stephan J. Sanders, Michael C. Schatz, Michael Wigler, Deborah A Nickerson, Kali T Witherspoon, Niklas Krumm, Shrikant M Mane
2014-12-18

Structural biology of presenilin 1 complexes

Gerold Schmitt-Ulms, Roger B Dodd, Peter St George-Hyslop
2014-10-23

Sorting nexin 27 regulates Aβ production through modulating γ-secretase activity
2014-09-16

DISC1 regulates trafficking and processing of APP and Aβ generation

Nicholas J Brandon
2014-10-21

The role of the retromer complex in aging-related neurodegeneration: a molecular and genomic review
2014-09-28

Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models

Michael E Ward, Lennart Mucke
2014-05-31

ABCA7 in Alzheimer's Disease

Jin-Tai Yu, Lan Tan
2014-09-12

Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients

Kuen-Jer Tsai, Pang-hsien Tu, Yun-Ru Chen
2014-08-15

Amyloid-β oligomers as a template for secondary amyloidosis in Alzheimer's disease

Diana L. Castillo-Carranza, Rakez Kayed, Marcos J Guerrero-Muñoz, Cristian A. Lasagna Reeves
2014-03-23

TDP-43 is a key player in the clinical features associated with Alzheimer's disease

Dennis W. Dickson, Melissa E. Murray, Glenn E. Smith, Leonard Petrucelli, Ronald C. Petersen, Clifford Jack, Nirubol Tosakulwong, David S Knopman, Bradley F Boeve, Matthew L. Senjem, Stephen Weigand, Jennifer L Whitwell, Keith A Josephs, Robert J Ivnik, Joseph E Parisi, Amanda M Liesinger
2014-12-10

Tau aggregation and its interplay with amyloid-β.

Lars M. Ittner, Rebecca M. Nisbet, Juan Carlos Polanco, Jürgen Götz
2014-11-14

Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease
2014-01-21

Methylene blue does not reverse existing neurofibrillary tangle pathology in the rTg4510 mouse model of tauopathy

Tara L Spires-Jones, Bradley Hyman, Rose Pitstick, George Carlson, Manuela Polydoro, Allyson D Roe
2014-09-12

Lost after translation: missorting of Tau protein and consequences for Alzheimer disease

Eckhard Mandelkow
2014-04-01

Activity-dependent tau protein translocation to excitatory synapse is disrupted by exposure to amyloid-beta oligomers.

Fabien Lanté, Alain Buisson
2014-06-05

Ryanodine receptors: physiological function and deregulation in Alzheimer disease

Frédéric Checler, Mounia Chami
2014-09-01

Eph receptors: new players in Alzheimer's disease pathogenesis

Frédéric Checler
2013-09-12

Neurodegenerative lesions: seeding and spreading
2013-12

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

Jean-Charles Lambert, Carla Ibrahim-Verbaas, Denise Harold, Céline Bellenguez, Joshua C Bis, Vincent Chouraki, Chiao-Feng Lin, M. Arfan Ikram, Agustín Ruíz, Florence Pasquier, Najaf Amin, Claudine Berr, Vincent Deramecourt, Simon Lovestone, Luc Letenneur, M. Ilyas Kamboh, Stephen Todd, Peter St George-Hyslop, Antony Bayer, Debby W Tsuang, Magda N. Tsolaki, Paola Bossù, Sandro Sorbi, Florentino Sanchez-Garcia, Nick C. Fox, Carol Brayne, Fiona E. Matthews, Patrizia Mecocci, Francesco Panza, Paolo Caffarra, Benedetta Nacmias, Cristina Razquin, Pau Pastor, Michael C. O'Donovan, Clive Holmes, Alexis Brice, Karen Ritchie, Kathryn L. Lunetta, Christophe Tzourio, Markus M. Nöthen, Caroline Graff, Peter Holmans, Lindsay A. Farrer, Sudha Seshadri, Philippe Amouyel, Albert Hofman, Jerome I Rotter, Albert V. Smith, Carlos Cruchaga, Ian Craig, Alison Goate, Anthony R Green, Richard H Myers, Jordi Clarimón, Janet T. Powell, Bruce M. Psaty, Christine Van Broeckhoven, John Hardy, Werner Maier, Richard Mayeux, Mark Lathrop, Cornelia M. van Duijn, Benjamin Grenier-Boley, Kara L Hamilton-Nelson, European Alzheimer's Disease Initiative (EADI), Pascale Barberger-Gateau, Lorna M. Lopez, Amanda J Bennett, Maria Candida Deniz Naranjo, Peter B. Jones, Alan J. Thomas, Jean-François Dartigues
2013-01-10

Variant of TREM2 associated with the risk of Alzheimer's disease

Kári Stefánsson, Knut Engedal, Dan Rujescu, Augustine Kong, Hreinn Stefansson, Unnur Þorsteinsdóttir, Cornelia M. van Duijn, Albert Hofman, Ingileif Jonsdottir, M. Arfan Ikram, Ole A. Andreassen, Srdjan Djurovic, Carla Ibrahim-Verbaas, Harald Hampel, Ina Giegling, James J Lah, Stacy Steinberg, Jon Snaedal, Johanna Huttenlocher, Thorlakur Jonsson, Allan Levey, Ingun D. Ulstein
2013-05-05

Pathway-based approaches for sequencing-based genome-wide association studies

Guodong Wu

Articolo - wd:Q47878052

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