Graham Ladds

2000 -

činnosť: výskumník

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Articles 51

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2021-03-03

Structure-based identification of dual ligands at the A<sub>2A</sub>R and PDE10A with anti-proliferative effects in lung cancer cell-lines

Marcel Bermudez, Robert C Glen, Graham Ladds
2021-06-23

CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells

David R Poyner, Mark Wigglesworth, Graham Ladds
2020-03-25

Correction to Insights to the Binding of a Selective Adenosine A3 Receptor Antagonist using Molecular Dynamic Simulations, MM-PBSA and MM-GBSA Free Energy Calculations, and Mutagenesis

Graham Ladds, Antonios Kolocouris
2020-09-01

Correction to Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity

Martin Lochner, Graham Ladds
2020-11-04

Combinatorial expression of GPCR isoforms affects signalling and drug responses

Maria Marti-Solano, Abigail Pearce, Junmin Peng, Andrew B Tobin, Graham Ladds, Graeme Milligan, David E. Gloriam, Manojkumar A Puthenveedu, Mohan Madan Babu, Christian Munk
2020-11-25

Author Correction: Combinatorial expression of GPCR isoforms affects signalling and drug responses

Maria Marti-Solano, Abigail Pearce, Junmin Peng, Andrew B Tobin, Graham Ladds, Graeme Milligan, David E. Gloriam, Manojkumar A Puthenveedu, Mohan Madan Babu
2019-11-11

RAMP3 determines rapid recycling of atypical chemokine receptor-3 for guided angiogenesis

Graham Ladds
2019-12-03

Insights to the Binding of a Selective Adenosine A3 Receptor Antagonist Using Molecular Dynamic Simulations, MM-PBSA and MM-GBSA Free Energy Calculations, and Mutagenesis

Graham Ladds, Antonios Kolocouris
2018-01-12

Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor

Graham Ladds
2018-07-09

Emerging patents in the therapeutic areas of glioma and glioblastoma.

Graham Ladds
2018-08-20

BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma

Fazal Hadi, Maria Francesca Santolla, Graham Ladds, Pentao Liu, Joo-Hyeon Lee, Walid T Khaled
2018-08-13

Engineering a model cell for rational tuning of GPCR signaling

Graham Ladds
2017-08-10

Hyperglycaemia does not affect antigen-specific activation and cytolytic killing by CD8+ T cells in vivo

F. Susan Wong, Graham Ladds, Anne Cooke
2017-12-30

Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases.

Andreas Bender, Robert C Glen, Lewis H Mervin, Jose Brea, Eddy Sotelo, Graham Ladds
2017-04-05

The effects of RAMPs upon cell signalling.

Graham Ladds, David R Poyner
2016-10-14

Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of Receptors

Juan Carlos Mobarec, Simon J Dowell, Graham Ladds, David R Poyner, Christopher A. Reynolds
2016-02-09

Feedback activation of neurofibromin terminates growth factor-induced Ras activation

Robby Markwart, Ian A. Prior, Graham Ladds
2016-04-01

Receptor activity-modifying proteins; multifunctional G protein-coupled receptor accessory proteins

Debbie Hay, Christopher Walker, Graham Ladds, David R Poyner, Joseph Gingell
2016-12-01

Receptor activity-modifying protein-directed G protein signaling specificity for the calcitonin gene-related peptide family of receptors

Simon J Dowell, Juan Carlos Mobarec, Graham Ladds
2016-02-01

Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity

Simon J Dowell, Martin Lochner, Graham Ladds
2015-11-16

GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation

Elisa Vergari, Benoit Hastoy, Koenraad Philippaert, Andrei I Tarasov, Graham Ladds, Manuela Zaccolo, Albert Salehi, Patrik Rorsman, Antony Giuseppe Galione, Paul Johnson, Reshma D Ramracheya, Thomas M Reinbothe, Makoto Shigeto, Margarita V Chibalina, Nils J G Rorsman
2015-08-01

Ras activation revisited: role of GEF and GAP systems

Robby Markwart, Graham Ladds
2015-07-21

Modulation of Glucagon Receptor Pharmacology by Receptor Activity-modifying Protein-2 (RAMP2).

David R Poyner, Simon J Dowell, Graham Ladds, Timothy M. Skerry
2015-03-20

Cortical oscillatory dynamics and benzodiazepine-site modulation of tonic inhibition in fast spiking interneurons

Gavin L Woodhall, Stephen D. Hall, Ian M. Stanford, Graham Ladds
2014-12-09

Image based validation of dynamical models for cell reorientation

Graham Ladds, Till Bretschneider
2014-08-01

Investigating G protein signalling bias at the glucagon-like peptide-1 receptor in yeast

David R Poyner, Simon J Dowell, Graham Ladds
2014-09-02

Parameter identification problems in the modelling of cell motility.

Graham Ladds, Chandrasekhar Venkataraman
2014-08-23

One motif to bind them: A small-XXX-small motif affects transmembrane domain 1 oligomerization, function, localization, and cross-talk between two yeast GPCRs.

Graham Ladds, Ann M Dixon, Antonia Lock
2013

The coordination of cell growth during fission yeast mating requires Ras1-GTP hydrolysis

Graham Ladds
2013-07-03

The role of the RACK1 ortholog Cpc2p in modulating pheromone-induced cell cycle arrest in fission yeast

Graham Ladds
2013-03-20

Quantitative analysis of human ras localization and function in the fission yeast Schizosaccharomyces pombe

Till Bretschneider, Graham Ladds
2011-01-01

Heterologous expression of GPCRs in fission yeast.

Graham Ladds

Human - wd:Q48511379

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