Chris Goodnow

1959 -

country of citizenship: United States of America, Australia

educated at: WEHI

award received: Fellow of the Royal Society, Fellow of the Australian Academy of Science, Gottschalk Medal

Christopher Carl Goodnow (born 19 September 1959) is an immunology researcher and the current executive director of the Garvan Institute of Medical Research. He holds the Bill and Patricia Ritchie Foundation Chair and is a Conjoint Professor in the faculty of medicine at UNSW Sydney. He holds dual Australian and US citizenship. Source: Wikipedia (en)

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Articles 165

Date

Title

Authors

2021-05-13

Antigen-driven EGR2 expression is required for exhausted CD8<sup>+</sup> T cell stability and maintenance

Madison J Kelly, Timothy Peters, Luciano G. Martelotto, Sarah Sharon Gabriel, Daniel Utzschneider, Jane Oliaro, Ricky W Johnstone, Axel Kallies, Chris Goodnow, Ian A. Parish
2020-08-27

Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens

Deborah L Burnett, David Langley, Emily Wilson, Chris Goodnow
2020-10-28

COVID-19, varying genetic resistance to viral disease, and immune tolerance checkpoints

Chris Goodnow
2020-12-17

Loss of hnRNPLL-dependent splicing of Ptprc has no impact on B-cell development, activation and terminal differentiation into antibody-secreting cells

Chris Goodnow
2019-09-18

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

Nathan W Zammit, Owen M Siggs, Keisuke Horikawa, Stephen Daley, Amanda Russell, Marcel E. Dinger, David Zahra, Geeta Chaudhri, Gunasegaran Karupiah, Anselm Enders, Colin Jackson, Craig N Jenne, Lewis L Lanier, Matthew H Spitzer, Benjamin Porebski, Ashley Buckle, Stuart Tangye, Cecile King, Murray Cox, Wilson Phung, Daniel Christ, Chris Goodnow, Shane T Grey, Garry P. Nolan, Yogesh S Jeelall, Jeanette E Villanueva, Peter D Mabbitt, Paul Gray, Robert Brink, Mark J. Cowley, Maria E. Craig, David Langley
2019-09-26

Clonal redemption and clonal anergy as mechanisms to balance B cell tolerance and immunity

Deborah L Burnett, Daniel Christ, Chris Goodnow
2019-11-01

A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

Hui-Fern Koay, Daniela Amann-Zalcenstein, Stephen Daley, Iain Comerford, Carly E Gregor, Peter Hickey, Jeffrey Y W Mak, Yovina Sontani, Axel Kallies, Zhenjun Chen, Simone Nüssing, Katherine Kedzierska, Laura K. Mackay, Shaun R McColl, Elissa K. Deenick, David P. Fairlie, James McCluskey, Chris Goodnow, Gabrielle Belz, Shalin H Naik, Daniel G Pellicci, Dale I Godfrey
2019-02-01

DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns

Joanne H Reed, Mark Rubin, Lisa G Horvath, Chris Goodnow
2019-02-20

B cell-intrinsic requirement for STK4 in humoral immunity in mice and human subjects

Elissa K. Deenick, Chris Goodnow, Cindy S Ma, Luigi D Notarangelo
2019-07-16

High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes

Mandeep Singh, Ghamdan Al-Eryani, James M Ferguson, James Blackburn, Tri Giang Phan, Simon Junankar, Katherine J Jackson, Chris Goodnow, Martin A Smith, Alexander Swarbrick
2019-05-21

IRF2 transcriptionally induces GSDMD expression for pyroptosis

Nobuhiko Kayagaki, Opher S Kornfeld, Benjamin Haley, Merone Roose-Girma, Sarah K Kummerfeld, Eun Cho, Chris Goodnow, Edward M Bertram, Vishva Dixit
2018-02-27

Indirect presentation in the thymus limits naive and regulatory T-cell differentiation by promoting deletion of self-reactive thymocytes

Chris Goodnow, Stephen Daley
2018-02-23

STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles.

Jalila Alshekaili, Susan M Corley, Cindy S Ma, Chris Goodnow, Carola Garcia de Vinuesa, Stuart Tangye, Matthew C Cook
2018-04-01

Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination

Deborah L Burnett, David Langley, Peter Schofield, Jana R. Hermes, Tyani D Chan, Katherine Bourne, Joanne H Reed, Benjamin Porebski, Daniel Christ, Chris Goodnow
2018-08-01

B-cell receptor reconstruction from single-cell RNA-seq with VDJPuzzle

Simone Rizzetto, David Koppstein, Joanne H Reed, Curtis Cai, Chris Goodnow
2018-06-04

Understanding Immune Tolerance of Cancer: Re-Purposing Insights from Fetal Allografts and Microbes

Megan B Barnet, Chris Goodnow
2018-08-03

Molecular Profiling and Clonal Tracking of Secreted Rheumatoid Factors in Primary Sjögren's Syndrome

Joanne H Reed, William Murray-Brown, Tim K Chataway, Katherine J Jackson, Chris Goodnow
2018-05-03

αβ T-cell receptors with a central CDR3 cysteine are enriched in CD8αα intraepithelial lymphocytes and their thymic precursors

Chris Goodnow, Stephen Daley
2018-07-01

The Ubiquitin Ligase Adaptor NDFIP1 Selectively Enforces a CD8+ T Cell Tolerance Checkpoint to High-Dose Antigen

Julia M Marchingo, Jason A. Howitt, Chris Goodnow, Ian A. Parish
2017-03-17

Up-regulation of LFA-1 allows liver-resident memory T cells to patrol and remain in the hepatic sinusoids

Hayley A McNamara, James H. O’Connor, William R Heath, Patrick Bertolino, Chris Goodnow, Ian A. Parish, Anselm Enders
2017-06-14

Murine LRBA deficiency causes CTLA-4 deficiency in Tregs without progression to immune dysregulation

Ian A. Parish, Chris Goodnow
2017-06-12

Systems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansion

Anselm Enders, Ian A. Parish, Aaron Chuah, Keisuke Horikawa, Tiffany A Russell, Chris Goodnow
2017-05-12

IL-2 prevents deletion of developing T-regulatory cells in the thymus

Stephen Daley, Chris Goodnow
2017-11-08

A mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation

Moira O'Bryan, Samantha R Oakes, Simon Junankar, Zoya Kikhtyak, Andrew M K Law, Lesley E Castillo, Catherine L Piggin, Jesse Donovan, Chris Goodnow
2017-10-25

Structural basis of antigen recognition: crystal structure of duck egg lysozyme.

David Langley, Mahdi Zeraati, Mary Christie, Chris Goodnow, Daniel Christ
2017-07-12

Synergistic cooperation and crosstalk between MYD88L265P and mutations that dysregulate CD79B and surface IgM

James Q Wang, Yogesh S Jeelall, Peter Humburg, Hee Min Yoo, Chris Goodnow, Keisuke Horikawa
2016-07-16

A Novel Mutation in Nucleoporin 35 Causes Murine Degenerative Colonic Smooth Muscle Myopathy

Ian A. Parish, Lincon A. Stamp, Chris Goodnow, John B. Furness
2016-07-25

Inhibiting TLR9 and other UNC93B1-dependent TLRs paradoxically increases accumulation of MYD88L265P plasmablasts in vivo

James Q Wang, Chris Goodnow, Keisuke Horikawa
2016-09-06

A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton

Erin Janssen, Verónica Azcutia, Chris Goodnow, Dianne Cox
2016-05-26

Heterogeneity of Human Neutrophil CD177 Expression Results from CD177P1 Pseudogene Conversion

Zuopeng Wu, Thomas Ohnesorg, Wesley Lam, Walter P Abhayaratna, Andrew H Sinclair, Chris Goodnow
2016-05-24

DeepSNVMiner: a sequence analysis tool to detect emergent, rare mutations in subsets of cell populations

Dipti Talaulikar, Chris Goodnow
2016-06-13

Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization

Joanne H Reed, Jennifer Jackson, Daniel Christ, Chris Goodnow

Human - wd:Q5106685

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