Janne Backman

1968 -

country of citizenship: Finland

educated at: University of Helsinki

occupation: medical researcher, physician, university teacher

official website: researchportal.helsinki.fi/fi/persons/janne-backman

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Articles 98

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Title

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2019-04-26

Fluoroquinolone-related adverse events resulting in health service use and costs: A systematic review

Laura S M Kuula, Janne Backman
2019-04-20

Clinical Studies on Drug-Drug Interactions Involving Metabolism and Transport: Methodology, Pitfalls, and Interpretation

Aleksi Tornio, Janne Backman
2019-01-10

Clopidogrel and Gemfibrozil Strongly Inhibit the CYP2C8-Dependent Formation of 3-Hydroxydesloratadine and Increase Desloratadine Exposure In Humans

Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi, Janne Backman, Matti K Itkonen
2019-11-29

Itraconazole Increases Ibrutinib Exposure 10-Fold and Reduces Interindividual Variation-A Potentially Beneficial Drug-Drug Interaction

Tuija Tapaninen, Aleksi Tornio, Pertti J. Neuvonen, Mikko Niemi, Janne Backman, Mikko Neuvonen
2019-02-01

Critical Differences between Enzyme Sources in Sensitivity to Detect Time-Dependent Inactivation of CYP2C8

Helinä Kahma, Anne M Filppula, Mikko Neuvonen, Rheem A Totah, Janne Backman
2019-05-05

Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs

Kim Blomqvist, Natalie Linea Hauglund, Frederik Filip Stæger, Ting Du, Janne Backman, Pekka Rauhala, Maiken Nedergaard
2019-06-03

Use of busulfan in conditioning for allogeneic hematopoietic stem cell transplantation in adults: a survey by the Transplant Complications Working Party of the EBMT

Janne Backman, Dietger Niederwieser, Christian Koenecke, Grzegorz W Basak, Nicolaus Kröger, Mohamad Mohty, Anja van Biezen, Tapani Ruutu, Silvia Montoto, Christophe Peczynski
2019-05-14

Enantiospecific Pharmacogenomics of Fluvastatin

Aleksi Tornio, Wilma Kiander, Heidi Kidron, Janne Backman, Mikko Niemi
2018-01-30

Implications of inter-correlation between hepatic CYP3A4-CYP2C8 enzymes for the evaluation of drug-drug interactions: a case study with repaglinide

Kosuke Doki, Brahim Achour, Aleksi Tornio, Janne Backman, Amin Rostami-Hodjegan
2018-04-12

Pulmonary administration of a dry powder formulation of the antifibrotic drug tilorone reduces silica-induced lung fibrosis in mice

Ville Vartiainen, Janne Backman, Emmi I Joensuu
2018-08-09

Clopidogrel Increases Dasabuvir Exposure With or Without Ritonavir, and Ritonavir Inhibits the Bioactivation of Clopidogrel

Matti K Itkonen, Aleksi Tornio, Mikko Niemi, Janne Backman
2018-08-30

Voriconazole greatly increases the exposure to oral buprenorphine

Janne Backman, Pertti J. Neuvonen, Klaus Olkkola, Teijo I Saari, Nora Hagelberg
2018-01-01

Cytochrome P450 in Pharmacogenetics: An Update

Aleksi Tornio, Janne Backman
2018-08-09

In Vitro Screening of Six Protein Kinase Inhibitors for Time-Dependent Inhibition of CYP2C8 and CYP3A4: Possible Implications with regard to Drug-Drug Interactions

Janne Backman
2018-08-20

CYP3A4*22 Impairs the Elimination of Ticagrelor, But Has No Significant Effect on the Bioactivation of Clopidogrel or Prasugrel

Aleksi Tornio, Janne Backman
2018-09-17

Response to "Interaction of Dasabuvir With Clopidogrel: Did Predictions by Physiologically Based Pharmacokinetics Modeling Pass the Test?"

Aleksi Tornio, Janne Backman
2017-02-15

Simvastatin pre-treatment improves survival and mitochondrial function in a 3-day fluid-resuscitated rat model of sepsis

Michael Bauer, Mervyn Singer, Janne Backman, Daniel F McAuley
2017-12-11

Prevention of chemotherapy-induced cachexia by ACVR2B ligand blocking has different effects on heart and skeletal muscle

Janne Backman, Riikka Kivelä, Juha J Hulmi, Olli Ritvos
2017-11-14

Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions .

Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi, Helinä Kahma, Matti K Itkonen, Anne M Filppula, Aleksi Tornio, Janne Backman, Mikko T Holmberg, E Katriina Tarkiainen
2017-10-08

Effects of Genetic Variants on Carboxylesterase 1 Gene Expression, and Clopidogrel Pharmacokinetics and Antiplatelet Effects.

Aleksi Tornio, Jussi Pihlajamäki, Mikko Niemi, Matti K Itkonen, Janne Backman, Pertti J. Neuvonen, Mikko Neuvonen, Mikko T Holmberg, E Katriina Tarkiainen
2017-12-23

Clopidogrel but Not Prasugrel Significantly Inhibits the CYP2C8-Mediated Metabolism of Montelukast in Humans

Aleksi Tornio, Matti K Itkonen, Mikko Niemi, Janne Backman
2017-11-06

Comprehensive Pharmacogenomic Study Reveals an Important Role of UGT1A3 in Montelukast Pharmacokinetics.

Aleksi Tornio, Jussi Pihlajamäki, Mikko Niemi, Janne Backman
2016-10-31

VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection

Riikka Kivelä, Janne Backman, Kari Alitalo, Juha J Hulmi
2016-11-03

Rifampicin decreases exposure to sublingual buprenorphine in healthy subjects

Pertti J. Neuvonen, Janne Backman, Klaus Olkkola, Nora Hagelberg
2016-01-01

Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions

Pertti J. Neuvonen, Anne M Filppula, Mikko Niemi, Janne Backman
2016-08-31

Role of gemfibrozil as an inhibitor of CYP2C8 and membrane transporters

Pertti J. Neuvonen, Aleksi Tornio, Mikko Niemi, Janne Backman
2016-05-24

The effects of intravenous lipid emulsion on hemodynamic recovery and myocardial cell mitochondrial function after bupivacaine toxicity in anesthetized pigs

Janne Backman
2016-10-05

Pilot Study of Propofol-induced Slow Waves as a Pharmacologic Test for Brain Dysfunction after Brain Injury

Jukka Kortelainen, Janne Backman
2016-08-10

Voriconazole more likely than posaconazole increases plasma exposure to sublingual buprenorphine causing a risk of a clinically important interaction.

Janne Backman, Pertti J. Neuvonen, Klaus Olkkola, Nora Hagelberg
2016-06-03

Clopidogrel Markedly Increases Plasma Concentrations of CYP2C8 Substrate Pioglitazone.

Aleksi Tornio, Mikko Niemi, Janne Backman, Matti K Itkonen, Pertti J. Neuvonen, Mikko Neuvonen
2016-04-11

Stable isotope and calcareous nannofossil assemblage record of the late Paleocene and early Eocene (Cicogna section)

Edoardo Dallanave, Giovanni Muttoni, Gerald R. Dickens, Claudia Agnini, Janne Backman, Heiko Pälike
2016-04-15

Major perturbations in the global carbon cycle and photosymbiont-bearing planktic foraminifera during the early Eocene

Eliana Fornaciari, Luca Giusberti, Gerald R. Dickens, Claudia Agnini, Janne Backman, Valeria Luciani

Human - wd:Q51368670

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Janne Backman