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Human pluripotent reprogramming with CRISPR activators.

author

Juha Kere

1958 -

Diego Balboa

Eeva-Mari Jouhilahti

Maxim M Bespalov

Shintaro Katayama

Kaarel Krjutškov

1981 -

published in: Nature Communications

date of publication: 2018-07-06

language: English

main subject: CRISPR, pluripotency

Cites articles 52

Date

Title

Authors

2018-01-09

CRISPR-Based Chromatin Remodeling of the Endogenous Oct4 or Sox2 Locus Enables Reprogramming to Pluripotency.

Lei S Qi
2017-06-01

RNA-Guided Activation of Pluripotency Genes in Human Fibroblasts

Lars Bolund, Poul Hyttel
2017-04-03

CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome

Alexias Safi, Gregory E. Crawford, Lingyun Song
2017-03-01

Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration

Hiroyuki Kamao, Kenichi Yoshida, Azusa Tanaka, Masayo Takahashi, Shinya Yamanaka
2017-02-23

Exploratory bioinformatics investigation reveals importance of "junk" DNA in early embryo development
2016-11-01

The impact of transposable elements on mammalian development

Ian R. Adams, Thomas J Widmann
2016-09-23

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation

Jacob E Corn, Max A Horlbeck, Ryan A Pak, Martin Kampmann, Jonathan Weissman
2016-08-30

The human PRD-like homeobox gene LEUTX has a central role in embryo genome activation

Juha Kere, Alvaro Plaza Reyes, Liselotte Vesterlund, Shintaro Katayama, Sten Linnarsson, Outi Hovatta, Eeva-Mari Jouhilahti, Fredrik Lanner, Kaarel Krjutškov, Elo Madissoon
2016-08-09

Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells

Kam W. Leong, Andrew F Adler
2016-07-14

Characterization and target genes of nine human PRD-like homeobox domain genes expressed exclusively in early embryos

Juha Kere, Elisabet Einarsdottir, Eeva-Mari Jouhilahti, Kaarel Krjutškov, Sten Linnarsson, Outi Hovatta, Liselotte Vesterlund, Fredrik Lanner, Shintaro Katayama, Elo Madissoon
2016-06-13

Evolutionary origin and functional divergence of totipotent cell homeobox genes in eutherian mammals

Ignacio Maeso, Thomas L Dunwell, Chris Wyatt, Ferdinand Marlétaz, Juan A. Bernal, Manuel Irimia, Peter Holland
2016-05-23

Comparison of Cas9 activators in multiple species

Emma J K Kowal, Ben S Ewen-Campen, Benjamin E Housden, Norbert Perrimon, George M. Church, Benjamin W Pruitt
2016-04-05

Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos

Sten Linnarsson, Alvaro Plaza Reyes, Björn Reinius, Qiaolin Deng, Rickard Sandberg, Fredrik Lanner
2016-03-31

Cas9 Functionally Opens Chromatin
2016-02-17

Molecular features of cellular reprogramming and development

Alexander Meissner
2016-02-13

Single-cell transcriptome analysis of endometrial tissue

Juha Kere, Shintaro Katayama, Maria Vera-Rodriguez, Triin Laisk-Podar, Hindrek Teder, Elisabet Einarsdottir, Andres Salumets
2016-01-01

Editing the epigenome: technologies for programmable transcription and epigenetic modulation
2016-01-19

Conversion of embryonic stem cells into extraembryonic lineages by CRISPR-mediated activators
2016-01

Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation
2015-10-26

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements

Alexias Safi, Gregory E. Crawford, Lingyun Song
2015-09-11

Novel PRD-like homeodomain transcription factors and retrotransposon elements in early human development

Shintaro Katayama, Liselotte Vesterlund, Sten Linnarsson, Outi Hovatta, Elo Madissoon, Marisa Jaconi, Juha Kere
2015-09-01

Conditionally Stabilized dCas9 Activator for Controlling Gene Expression in Human Cell Reprogramming and Differentiation

Diego Balboa, Ras Trokovic
2015-07-01

Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency

George Q. Daley, Eric Lander, Rahul Karnik, John L. Rinn, Alexander Meissner, Cole Trapnell, Tarjei S Mikkelsen, John G Doench, Casey A Gifford
2015-06-02

Generation of iPSC line HEL24.3 from human neonatal foreskin fibroblasts

Ras Trokovic
2015-04-06

Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers

Isaac B Hilton, Timothy E. Reddy
2015-03-16

Functional annotation of native enhancers with a Cas9-histone demethylase fusion

Nicola A Kearns, Noah J Silverstein
2015-03-02

Highly efficient Cas9-mediated transcriptional programming

Noah Davidsohn, Benjamin W Pruitt, Benjamin E Housden, Norbert Perrimon, George M. Church
2015-02-01

Transcription factor binding dynamics during human ES cell differentiation

Alexander Meissner, Amir Giladi, Andreas Gnirke
2015-01-05

ATAC-seq: A Method for Assaying Chromatin Accessibility Genome-Wide

William Greenleaf, Jason D. Buenrostro
2014-12-10

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

Jonathan S. Gootenberg, Patrick D Hsu
2014-10-23

A CRISPR/Cas9-based system for reprogramming cell lineage specification

Kam W. Leong
2014-09-15

Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancers

Article - wd:Q55509998

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