Eric W Hewitt

pendidikan: Universitas Manchester, University of Reading

pekerjaan: peneliti

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Artikel 42

Date

Judul

Pengarang

2019-09-25

Structural mapping of oligomeric intermediates in an amyloid assembly pathway

Theodoros K Karamanos, Antonio N. Calabrese, Sophia C. Goodchild, Emma E Cawood, Eric W Hewitt, Sheena Radford
2018-12-01

A new era for understanding amyloid structures and disease

Matthew G Iadanza, Eric W Hewitt, Neil Ranson, Sheena Radford
2017-09-22

Why are Functional Amyloids Non-Toxic in Humans?

Eric W Hewitt
2016-10-01

Cellular proteostasis: degradation of misfolded proteins by lysosomes

Eric W Hewitt
2016-02-13

Comparison of the aggregation of homologous β2-microglobulin variants reveals protein solubility as a key determinant of amyloid formation

Sheena Radford, Clare L Pashley, Eric W Hewitt
2015-04-20

pH-induced molecular shedding drives the formation of amyloid fibril-derived oligomers

Sheena Radford, Neil Ranson, Matthew G Iadanza, Sophia C. Goodchild, Eric W Hewitt, Theodoros Karamanos, Roman Tuma
2015-11-02

Amyloid Fibres: Inert End-Stage Aggregates or Key Players in Disease?

Sheena Radford, Patricija van Oosten-Hawle, Eric W Hewitt
2014

β2-Microglobulin amyloid fibril-induced membrane disruption is enhanced by endosomal lipids and acidic pH

Neil Ranson, Sheena Radford, Wei-Feng Xue, Sophia C. Goodchild, Paul A Beales, Rebecca F. Thompson, Eric W Hewitt
2014-06-09

Analysis of familial hemophagocytic lymphohistiocytosis type 4 (FHL-4) mutant proteins reveals that S-acylation is required for the function of syntaxin 11 in natural killer cells

Ombretta Foresti, Eric W Hewitt
2014-03-07

Immunologic human renal allograft injury associates with an altered IL-10/TNF-α expression ratio in regulatory B cells

Eric W Hewitt, Maria Hernandez-Fuentes
2014-11-05

β2-microglobulin amyloid fibrils are nanoparticles that disrupt lysosomal membrane protein trafficking and inhibit protein degradation by lysosomes

Sheena Radford, Wei-Feng Xue, Eric W Hewitt
2013-08-01

Aggregation modulators interfere with membrane interactions of β2-microglobulin fibrils

Wei-Feng Xue, Sheena Radford, Raz Jelinek, Eric W Hewitt
2012-11-26

Direct three-dimensional visualization of membrane disruption by amyloid fibrils

Sheena Radford, Wei-Feng Xue, Elena V. Orlova, Andrew L Hellewell, Raz Jelinek, Eric W Hewitt, Helen Saibil
2011-11-09

Characterization of the response of primary cells relevant to dialysis-related amyloidosis to β2-microglobulin monomer and fibrils

Sheena Radford, Eric W Hewitt
2011-08-28

Ligand binding to distinct states diverts aggregation of an amyloid-forming protein

Sheena Radford, Alison E. Ashcroft, Andrew L Hellewell, Eric W Hewitt
2010-01-29

Fibril fragmentation in amyloid assembly and cytotoxicity: when size matters

Sheena Radford, Wei-Feng Xue, Eric W Hewitt
2009-09-01

Natural killer cell cytotoxicity: how do they pull the trigger?

Eric W Hewitt
2009-05-13

Dependence of the localization and function of the human cytomegalovirus protein US6 on the transporter associated with antigen processing

Eric W Hewitt
2009-04-15

Kaposi's sarcoma-associated herpesvirus RTA promotes degradation of the Hey1 repressor protein through the ubiquitin proteasome pathway

Adrian Whitehouse, Eric W Hewitt
2009-10-06

Fibril fragmentation enhances amyloid cytotoxicity

Wei-Feng Xue, Sheena Radford, Andrew L Hellewell, Eric W Hewitt
2008-01-16

Structural and Functional Dissection of the Human Cytomegalovirus Immune Evasion Protein US6.

Eric W Hewitt
2007-08-08

Investigation into the role of macrophages in the formation and degradation of beta2-microglobulin amyloid fibrils

Sheena Radford, Eric W Hewitt
2007-01-31

Organelle proteomics: identification of the exocytic machinery associated with the natural killer cell secretory lysosome

Eric W Hewitt
2007-05-02

Specific glycosaminoglycans promote unseeded amyloid formation from beta2-microglobulin under physiological conditions

Sheena Radford, Eric W Hewitt
2006-02-01

A systematic study of the effect of physiological factors on beta2-microglobulin amyloid formation at neutral pH.

Thomas R Jahn, Sheena Radford, Eric W Hewitt, Glenys A Tennent
2005-08-01

Competing pathways determine fibril morphology in the self-assembly of beta2-microglobulin into amyloid.

Sheena Radford, Eric W Hewitt
2004-09-01

Virus subversion of protective immunity

Eric W Hewitt
2003-02-01

The ABC-transporter signature motif is required for peptide translocation but not peptide binding by TAP

Eric W Hewitt, Paul J Lehner
2003-10-01

The MHC class I antigen presentation pathway: strategies for viral immune evasion

Eric W Hewitt
2002-03-01

Synaptotagmin I-DeltaC2B. A novel synaptotagmin isoform with a single C2 domain in the bovine adrenal medulla

Eric W Hewitt, Daniel F Cutler
2002-05-01

Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation

Eric W Hewitt, Philip G Stevenson, Paul J Lehner
2002-09-01

Powering the peptide pump: TAP crosstalk with energetic nucleotides

Peter M van Endert, Loredana Saveanu, Eric W Hewitt, Paul J Lehner

Human - wd:Q56441706

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